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Giorgio Longari

Publications and source records attributed to Giorgio Longari.

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Towards Reliable and Reproducible Fetal Brain Biometry: A Deep Learning Approach Using MRI

Fetal brain biometry is essential for quantitative assessment of brain development, supporting gestational age estimation, developmental monitoring, and detection of abnormalities. In clinical practice, measurements are manually performed, making them time-consuming and prone to variability. While automated approaches have been proposed, reproducible methods remain limited, particularly those providing anatomically interpretable landmark localization. We present a fully automated deep learning-based framework for reliable and reproducible brain biometry from 3D super-resolution-reconstructed fetal brain MRI. The proposed four-step pipeline derives biometric parameters by jointly estimating linear measurements and their corresponding anatomical landmarks. A 3D convolutional neural network is trained to regress landmark coordinates from brain segmentation label maps, followed by measurement-specific geometric optimization to refine landmark positions and compute measurements. The pipeline is evaluated on two publicly available fetal MRI datasets comprising 150 volumes (gestational age range: 20-37 weeks) acquired across different scanners and protocols, assessing five key biometric measurements across varying acquisition settings and providing a comprehensive evaluation of both measurement accuracy and landmark localization using quantitative metrics and visual assessment. Compared with the only available automated pipeline, the proposed method achieves comparable or improved accuracy for most measurements. In conclusion, we introduce a straightforward pipeline for reliable biometry estimations, with efficiency, interpretability and scalability that support integration into clinical workflows.

cs.CV

Geometric Learning of Canonical Parameterizations of $2D$-curves

Most datasets encountered in computer vision and medical applications present symmetries that should be taken into account in classification tasks. A typical example is the symmetry by rotation and/or scaling in object detection. A common way to build neural networks that learn the symmetries is to use data augmentation. In order to avoid data augmentation and build more sustainable algorithms, we present an alternative method to mod out symmetries based on the notion of section of a principal fiber bundle. This framework allows the use of simple metrics on the space of objects in order to measure dissimilarities between orbits of objects under the symmetry group. Moreover, the section used can be optimized to maximize separation of classes. We illustrate this methodology on a dataset of contours of objects for the groups of translations, rotations, scalings and reparameterizations. In particular, we present a $2$-parameter family of canonical parameterizations of curves, containing the constant-speed parameterization as a special case, which we believe is interesting in its own right. We hope that this simple application will serve to convey the geometric concepts underlying this method, which have a wide range of possible applications. The code is available at the following link: $\href{https://github.com/GiLonga/Geometric-Learning}{https://github.com/GiLonga/Geometric-Learning}$. A tutorial notebook showcasing an application of the code to a specific dataset is available at the following link: $\href{https://github.com/ioanaciuclea/geometric-learning-notebook}{https://github.com/ioanaciuclea/geometric-learning-notebook}$

cs.CV

Blending Concepts with Text-to-Image Diffusion Models

Diffusion models have dramatically advanced text-to-image generation in recent years, translating abstract concepts into high-fidelity images with remarkable ease. In this work, we examine whether they can also blend distinct concepts, ranging from concrete objects to intangible ideas, into coherent new visual entities under a zero-shot framework. Specifically, concept blending merges the key attributes of multiple concepts (expressed as textual prompts) into a single, novel image that captures the essence of each concept. We investigate four blending methods, each exploiting different aspects of the diffusion pipeline (e.g., prompt scheduling, embedding interpolation, or layer-wise conditioning). Through systematic experimentation across diverse concept categories, such as merging concrete concepts, synthesizing compound words, transferring artistic styles, and blending architectural landmarks, we show that modern diffusion models indeed exhibit creative blending capabilities without further training or fine-tuning. Our extensive user study, involving 100 participants, reveals that no single approach dominates in all scenarios: each blending technique excels under certain conditions, with factors like prompt ordering, conceptual distance, and random seed affecting the outcome. These findings highlight the remarkable compositional potential of diffusion models while exposing their sensitivity to seemingly minor input variations.

cs.CV

Advances in Automated Fetal Brain MRI Segmentation and Biometry: Insights from the FeTA 2024 Challenge

Accurate fetal brain tissue segmentation and biometric analysis are essential for studying brain development in utero. The FeTA Challenge 2024 advanced automated fetal brain MRI analysis by introducing biometry prediction as a new task alongside tissue segmentation. For the first time, our diverse multi-centric test set included data from a new low-field (0.55T) MRI dataset. Evaluation metrics were also expanded to include the topology-specific Euler characteristic difference (ED). Sixteen teams submitted segmentation methods, most of which performed consistently across both high- and low-field scans. However, longitudinal trends indicate that segmentation accuracy may be reaching a plateau, with results now approaching inter-rater variability. The ED metric uncovered topological differences that were missed by conventional metrics, while the low-field dataset achieved the highest segmentation scores, highlighting the potential of affordable imaging systems when paired with high-quality reconstruction. Seven teams participated in the biometry task, but most methods failed to outperform a simple baseline that predicted measurements based solely on gestational age, underscoring the challenge of extracting reliable biometric estimates from image data alone. Domain shift analysis identified image quality as the most significant factor affecting model generalization, with super-resolution pipelines also playing a substantial role. Other factors, such as gestational age, pathology, and acquisition site, had smaller, though still measurable, effects. Overall, FeTA 2024 offers a comprehensive benchmark for multi-class segmentation and biometry estimation in fetal brain MRI, underscoring the need for data-centric approaches, improved topological evaluation, and greater dataset diversity to enable clinically robust and generalizable AI tools.

cs.CV

How to Blend Concepts in Diffusion Models

For the last decade, there has been a push to use multi-dimensional (latent) spaces to represent concepts; and yet how to manipulate these concepts or reason with them remains largely unclear. Some recent methods exploit multiple latent representations and their connection, making this research question even more entangled. Our goal is to understand how operations in the latent space affect the underlying concepts. To that end, we explore the task of concept blending through diffusion models. Diffusion models are based on a connection between a latent representation of textual prompts and a latent space that enables image reconstruction and generation. This task allows us to try different text-based combination strategies, and evaluate easily through a visual analysis. Our conclusion is that concept blending through space manipulation is possible, although the best strategy depends on the context of the blend.

cs.CV