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Girish Kulkarni

Publications and source records attributed to Girish Kulkarni.

At least 37 records · Page 2Linked to original sources
arXiv2025

Development of a Miniaturized, Automated, and Cost-Effective Device for Enzyme-Linked Immunosorbent Assay

In this work, a miniaturized, automated, and cost-effective ELISA device is designed and implemented, without the utilization of conventional techniques such as pipetting or microfluidic valve technologies. The device has dimensions of 24 cm x 19 cm x 14 cm and weighs <3 Kg. The total hardware cost of the device is estimated to be approximately $1,200, which can be further reduced through optimization during scale-up production. 3D printed disposable parts, including the reagent reservoir disk and the microfluidic connector, have also been developed. IL-6 is used as a model system to demonstrate how the device provides an ELISA measurement. The cost per test is estimated to be less than ten dollars. The compactness, automated operation, along with the cost-effectiveness of this ELISA device, makes it suitable for point-of-care applications in resource-limited regions.

physics.med-ph↗
arXiv2025

Prospects of a statistical detection of the 21-cm forest and its potential to constrain the thermal state of the neutral IGM during reionization

The 21-cm forest signal is a promising probe of the Epoch of Reionization complementary to other 21-cm line observables and Ly$α$ forest signal. Prospects of detecting it have significantly improved in the last decade thanks to the discovery of more than 30 radio-loud quasars at these redshifts, upgrades to telescope facilities, and the notion that neutral hydrogen islands persist down to $z\lesssim 5.5$. We forward-model the 21-cm forest signal using semi-numerical simulations and incorporate various instrumental features to explore the potential of detecting the 21-cm forest at $z=6$, both directly and statistically, with the currently available (uGMRT) and forthcoming (SKA1-low) observatories. We show that it is possible to detect the 1D power spectrum of the 21-cm forest spectrum, especially at large scales of $k\lesssim8.5\,\rm MHz^{-1}$ with the $500\,\rm hr$ of the uGMRT time and $k\lesssim32.4\,\rm MHz^{-1}$ with the SKA1-low over $50\,\rm hr$ if the intergalactic medium (IGM) is $25\%$ neutral and these neutral hydrogen regions have a spin temperature of $\lesssim30\,\rm K$. On the other hand, we infer that a null-detection of the signal with such observations of 10 radio-loud sources at $z\approx6$ can be translated into constraints on the thermal and ionization state of the IGM which are tighter than the currently available measurements. Moreover, a null-detection of the 1D 21-cm forest power spectrum with only $50\,\rm hr$ of the uGMRT observations of 10 radio-loud sources can already be competitive with the Ly$α$ forest and 21-cm tomographic observations in disfavouring models of significantly neutral and cold IGM at $z=6$.

astro-ph.CO↗
arXiv2024

The ionizing photon budget and effective clumping factor in radiative transfer simulations calibrated to Lyman-alpha forest data

Recent JWST observations have allowed for the first time to obtain comprehensive measurements of the ionizing photon production efficiency $ξ_\text{ion} $ for a wide range of reionization-epoch galaxies. We explore implications for the inferred UV luminosity functions and escape fractions of ionizing sources in our suite of simulations. These are run with the GPU-based radiative transfer code ATON-HE and are calibrated to the XQR-30 Lyman-alpha forest data at $5 50$% at $z> 10$, disfavouring the oligarchic source model at very high redshift. The inferred effective clumping factors in our simulations are in the range of $3-6$, suggesting consistency between the observed ionizing properties of reionization-epoch galaxies and the ionizing photon budget in our simulations.

astro-ph.CO↗
arXiv2024

Radiative transfer of Lyman-$α$ photons at cosmic dawn with realistic gas physics

Lyman-$α$ photons enable the cosmic dawn 21-cm signal through a process called the Wouthuysen-Field effect. An accurate model of the signal in this epoch hinges on the accuracy of the computation of the Ly$α$ coupling, which requires one to calculate the specific intensity of Ly$α$ photons emitted from the first stars. Most traditional calculations of the Ly$α$ coupling assume a delta-function scattering cross-section, as the resonant nature of the Ly$α$ scattering makes an accurate radiative transfer (RT) solution computationally expensive. Attempts to improve upon this traditional approach using numerical RT have recently emerged. However, some of these treatments suffer from assumptions such as a uniform gas distribution, coherent scattering in the gas frame and isotropic scattering. While others which do not account for these only do so through certain schemes along with core-skipping algorithms. We present results from a self-consistent Monte Carlo RT simulations devoid of any of the assumptions in the previous work for the first time. We find that gas bulk motion is the most important effect to account for in RT resulting in an RMS difference of 38% in the 21-cm signal and anisotropic scattering being the least important effect contributing to less than 3% RMS difference in 21-cm signal. We also evaluate the 21-cm power spectrum and compare that with the traditional results at cosmic dawn. This work points the way towards higher-accuracy models to enable better inferences from future measurements.

astro-ph.CO↗
arXiv2024

Efficient characterization of spatial Schmidt modes of multiphoton entangled states produced from high-gain parametric down-conversion

The ability to efficiently characterize the spatial correlations of entangled states of light is critical for applications of many quantum technologies such as quantum imaging. Here, we demonstrate highly efficient theoretical and experimental characterization of the spatial Schmidt modes and the Schmidt spectrum of bright multiphoton entangled states of light produced from high-gain parametric down-conversion. In contrast to previous studies, we exploit the approximate quasihomogeneity and isotropy of the signal field and dramatically reduce the numerical computations involved in the experimental and theoretical characterization procedures. In our particular case where our experimental data sets consist of 5000 single-shot images of 256*256 pixels each, our method reduced the overall computation time by 2 orders of magnitude. This speed-up would be even more dramatic for larger input sizes. Consequently, we are able to rapidly characterize the Schmidt modes and Schmidt spectrum for a range of pump amplitudes and study their variation with increasing gain. Our results clearly reveal the broadening of the Schmidt modes and narrowing of the Schmidt spectrum for increasing gain with good agreement between theory and experiment.

quant-ph↗
arXiv2024

Impact of extragalactic point sources on the low-frequency sky spectrum and cosmic dawn global 21-cm measurements

Contribution of resolved and unresolved extragalactic point sources to the low-frequency sky spectrum is a potentially non-negligible part of the astrophysical foregrounds for cosmic dawn 21-cm experiments. The clustering of such point sources on the sky, combined with the frequency-dependence of the antenna beam, can also make this contribution chromatic. By combining low-frequency measurements of the luminosity function and the angular correlation function of extragalactic point sources, we develop a model for the contribution of these sources to the low-frequency sky spectrum. Using this model, we find that the contribution of sources with flux density $>10^{-6}\,$Jy to the sky-averaged spectrum is smooth and of the order of a few kelvins at 50--$200\,$MHz. We combine this model with measurements of the galactic foreground spectrum and weigh the resultant sky by the beam directivity of the conical log-spiral antenna planned as part of the Radio Experiment for the Analysis of Cosmic Hydrogen (REACH) project. We find that the contribution of point sources to the resultant spectrum is $\sim0.4\%$ of the total foregrounds, but still larger by at least an order of magnitude than the standard predictions for the cosmological 21-cm signal. As a result, not accounting for the point-source contribution leads to a systematic bias in 21-cm signal recovery. We show, however, that in the REACH case, this reconstruction bias can be removed by modelling the point-source contribution as a power law with a running spectral index. We make our code publicly available as a Python package labelled epspy.

astro-ph.CO↗
arXiv2024

Late-end reionization with ATON-HE: towards constraints from Lyman-$α$ emitters observed with JWST

We present a new suite of late-end reionization simulations performed with ATON-HE, a revised version of the GPU-based radiative transfer code ATON that includes helium. The simulations are able to reproduce the Ly$α$ flux distribution of the E-XQR-30 sample of QSO absorption spectra at $5 \lesssim z \lesssim 6.2$, and show that a large variety of reionization models are consistent with these data. We explore a range of variations in source models and in the early-stage evolution of reionization. Our fiducial reionization history has a midpoint of reionization at $z = 6.5$, but we also explore an `Early' reionization history with a midpoint at $z = 7.5$ and an `Extremely Early' reionization history with a midpoint at $z = 9.5$. Haloes massive enough to host observed Ly$α$ emitters are highly biased. The fraction of such haloes embedded in ionized bubbles that are large enough to allow high Ly$α$ transmission becomes close to unity much before the volume filling factor of ionized regions. For our fiducial reionization history this happens at $z = 8$, probably too late to be consistent with the detection by JWST of abundant Ly$α$ emission out to $z = 11$. A reionization history in our `Early' model or perhaps even our `Extremely Early' model may be required, suggesting a Thomson scattering optical depth in tension with that reported by Planck, but consistent with recent suggestions of a significantly higher value.

astro-ph.CO↗
arXiv2024

Robustness of direct measurements of the mean free path of ionizing photons in the epoch of reionization

Measurements of the mean free path of Lyman-continuum photons in the intergalactic medium during the epoch of reionization can help constrain the nature of the sources as well as sinks of hydrogen-ionizing radiation. A recent approach to this measurement has been to utilize composite spectra of multiple quasars at $z\sim 6$, and infer the mean free path after correcting the spectra for the presence of quasar proximity zones. This has revealed not only a steep drop in the mean free path from $z=5$ to $z=6$, but also potentially a mild tension with reionization simulations. We critically examine such direct measurements of the mean free path for biases due to quasar environment, incomplete reionization, and quasar proximity zones. Using cosmological radiative transfer simulations of reionization combined with one-dimensional radiative transfer calculations of quasar proximity zones, we find that the bias in the mean free path due to overdensities around quasars is minimal at $z\sim 6$. Patchiness of reionization at this redshift also does not affect the measurements significantly. Fitting our model to the data results in a mean free path of $λ_{\mathrm{mfp}}=1.49^{+0.47}_{-0.52}$~pMpc at $z=6$, which is consistent with the recent measurements in the literature, indicating robustness with respect to the modelling of quasar proximity zones. We also compare various ways in which the mean free path has been defined in simulations before the end of reionization. Overall, our finding is that recent measurements of the mean free path appear to be robust relative to several sources of potential bias.

astro-ph.CO↗
arXiv2024

Damping Wing-Like Features in the Stacked Ly$α$ Forest: Potential Neutral Hydrogen Islands at $z<6$

Recent quasar absorption line observations suggest that reionization may end as late as $z \approx 5.3$. As a means to search for large neutral hydrogen islands at $z<6$, we revisit long dark gaps in the Ly$β$ forest in VLT/X-Shooter and Keck/ESI quasar spectra. We stack the Ly$α$ forest corresponding to both edges of these Ly$β$ dark gaps and identify a damping wing-like extended absorption profile. The average redshift of the stacked forest is $z=5.8$. By comparing these observations with reionization simulations, we infer that such a damping wing-like feature can be naturally explained if these gaps are at least partially created by neutral islands. Conversely, simulated dark gaps lacking neutral hydrogen struggle to replicate the observed damping wing features. Furthermore, this damping wing-like profile implies that the volume-averaged neutral hydrogen fraction must be $\langle x_{\rm HI} \rangle \geq 6.1 \pm 3.9\%$ at $z = 5.8$. Our results offer robust evidence that reionization extends below $z=6$.

astro-ph.CO↗
arXiv2024

Evidence of Pop~III stars' chemical signature in neutral gas at z~6. A study based on the E-XQR-30 spectroscopic sample

This study explores the metal enrichment signatures attributed to the first generation of stars (PopIII) in the Universe, focusing on the E-XQR-30 sample. We aim to identify traces of Pop III metal enrichment by analyzing neutral gas in the interstellar medium of primordial galaxies and their satellite clumps, detected in absorption. To chase the chemical signature of PopIII stars, we studied metal absorption systems in the E-XQR-30 sample, selected through the detection of the OI absorption line at 1302A. The OI line is a reliable tracer of HI and allowed us to overcome the challenges posed by the Lyman-$α$ forest's increasing saturation at redshifts above $\sim5$ to identify Damped Lyman-$α$ systems (DLA). We detected and analyzed 29 OI systems at $z\geq5.4$, differentiating between proximate DLAs (PDLA) and intervening DLAs. Voigt function fits were applied to obtain ionic column densities, and relative chemical abundances were determined for 28 systems. These were then compared with the predictions of theoretical models. Our findings expand the study of OI systems at $z\geq5.4$ fourfold. No systematic differences were observed in the average chemical abundances between PDLAs and intervening DLAs. The chemical abundances in our sample align with literature systems at $z>4.5$, suggesting a similar enrichment pattern for this class of absorption systems. A comparison between these DLA-analogues at $4.5<z<6.5$ with a sample of very metal-poor DLAs at $2<z<4.5$ shows in general similar average values for the relative abundances, with the exception of [C/O], [Si/Fe] and [Si/O] which are significantly larger for the high-$z$ sample. Furthermore, the dispersion of the measurements significantly increases in the high-redshift bin. This increase is predicted by the theoretical models and indicates a potential retention of PopIII signatures in the probed gas. (Abridged)

astro-ph.GA↗
arXiv2024

E-XQR-30: The evolution of MgII, CII and OI across 2<z<6

Intervening metal absorbers in quasar spectra at $z > 6$ can be used as probes to study the chemical enrichment of the Universe during the Epoch of Reionization (EoR). This work presents the comoving line densities ($dn/dX$) of low ionisation absorbers, namely, Mg II (2796Å), C II (1334Å) and O I (1302Å) across $2 0.03$Å. For the first time, we present the comoving line densities of 131 weak ($W < 0.3$Å) intervening Mg II absorbers at $1.9 < z < 6.4$ which exhibit constant evolution with redshift similar to medium ($0.3 < W < 1.0$Å) absorbers. However, the cosmic mass density of Mg II - dominated by strong Mg II systems - traces the evolution of global star formation history from redshift 1.9 to 5.5. E-XQR-30 also increases the absorption path length by a factor of 50% for C II and O I whose line densities show a rising trend towards $z > 5$, in agreement with previous works. In the context of a decline in metal enrichment of the Universe at $z > 5$, the overall evolution in the incidence rates of absorption systems can be explained by a weak - possibly soft fluctuating - UV background. Our results, thereby, provide evidence for a late reionization continuing to occur in metal-enriched and therefore, biased regions in the Universe.

astro-ph.GA↗
arXiv2024

The 21-cm bispectrum from neutral hydrogen islands at z < 6

Spatial variations in the Lyman-$α$ forest opacity at $z<6$ seem to require a late end to cosmic reionization. In this picture, the universe contains neutral hydrogen 'islands' of up to 100 cMpc$/h$ in extent down to redshifts as low as $z\sim 5.3$. This delayed end to reionization also seems to be corroborated by various other observables. An implication of this scenario is that the power spectrum of the cosmological 21-cm signal at $z<6$ is enhanced relative to conventional reionization models by orders of magnitude. However, these neutral hydrogen islands are also predicted to be at the locations of the deepest voids in the cosmological large-scale structure. As a result, the distribution of the 21-cm signal from them is highly non-Gaussian. We derive the 21-cm bispectrum signal from these regions using high-dynamic-range radiative transfer simulations of reionization. We find that relative to conventional models in which reionization is complete at $z>6$, our model has a significantly larger value of the 21-cm bispectrum. The neutral islands also imprint a feature in the isosceles bispectrum at a characteristic scale of $\sim 1$ cMpc$^{-1}$. We also study the 21-cm bispectrum for general triangle configuration by defining a triangle index. It should be possible to detect the 21-cm bispectrum signal at $ν\gtrsim 200$ MHz using SKA1-LOW for 1080 hours of observation, assuming optimistic foreground removal.

astro-ph.CO↗
arXiv2024

Particle initialization effects on Lyman-$α$ forest statistics in cosmological SPH simulations

Confronting measurements of the Lyman-$α$ forest with cosmological hydrodynamical simulations has produced stringent constraints on models of particle dark matter and the thermal and ionization state of the intergalactic medium. We investigate the robustness of such models of the Lyman-$α$ forest, focussing on the effect of particle initial conditions on the Lyman-$α$ forest statistics in cosmological SPH simulations. We study multiple particle initialization algorithms in simulations that are designed to be identical in other respects. In agreement with the literature, we find that the correct linear theory evolution is obtained when a glass-like configuration is used for initial unperturbed gas particle positions alongside a regular grid configuration for dark matter particles and the use of non-identical initial density perturbations for gas and dark matter. However, we report that this introduces a large scale-dependent distortion in the one-dimensional Lyman-$α$ transmission power spectrum at small scales ($k > 0.05$ s/km). The effect is close to $50\%$ at $k\sim 0.1$ s/km, and persists at higher resolution. This can severely bias inferences in parameters such as the dark matter particle mass. By considering multiple initial conditions codes and their variations, we also study the impact of a variety of other assumptions and algorithmic choices, such as adaptive softening, background radiation density, particle staggering, and perturbation theory accuracy, on the matter power spectrum, the Lyman-$α$ flux power spectrum, and the Lyman-$α$ flux PDF. This work reveals possible pathways towards more accurate theoretical models of the Lyman-$α$ forest to match the quality of upcoming measurements.

astro-ph.CO↗
arXiv2024

Unveiling Dark Matter free-streaming at the smallest scales with high redshift Lyman-alpha forest

This study introduces novel constraints on the free-streaming of thermal relic warm dark matter (WDM) from Lyman-$α$ forest flux power spectra. Our analysis utilises a high-resolution, high-redshift sample of quasar spectra observed using the HIRES and UVES spectrographs ($z=4.2-5.0$). We employ a Bayesian inference framework and a simulation-based likelihood that encompasses various parameters including the free-streaming of dark matter, cosmological parameters, the thermal history of the intergalactic medium, and inhomogeneous reionization, to establish lower limits on the mass of a thermal relic WDM particle of $5.7\;\mathrm{keV}$ (at 95\% C.L.). This result surpasses previous limits from the Lyman-$α$ forest through reduction of the measured uncertainties due to a larger statistical sample and by measuring clustering to smaller scales ($k_{\rm max}=0.2\;\mathrm{km^{-1}\,s}$). The approximately two-fold improvement due to the expanded statistical sample suggests that the effectiveness of Lyman-$α$ forest constraints on WDM models at high redshifts are limited by the availability of high-quality quasar spectra. Restricting the analysis to comparable scales and thermal history priors as in prior studies ($k_{\rm max}<0.1\;\mathrm{km^{-1}\,s}$) lowers the bound on the WDM mass to $4.1\;\mathrm{keV}$. As the precision of the measurements increases, it becomes crucial to examine the instrumental and modelling systematics. On the modelling front, we argue that the impact of the thermal history uncertainty on the WDM particle mass constraint has diminished due to improved independent observations. At the smallest scales, the primary source of modeling systematic arises from the structure in the peculiar velocity of the intergalactic medium and inhomogeneous reionization.

astro-ph.CO↗
arXiv2024

A SPectroscopic survey of biased halos In the Reionization Era (ASPIRE): Impact of Galaxies on the CGM Metal Enrichment at z > 6 Using the JWST and VLT

We characterize the multiphase circumgalactic medium and galaxy properties at z = 6.0-6.5 in four quasar fields from the James Webb Space Telescope A SPectroscopic survey of biased halos In the Reionization Era (ASPIRE) program. We use the Very Large Telescope/X-shooter spectra of quasar J0305-3150 to identify one new metal absorber at z = 6.2713 with multiple transitions (OI, MgI, FeII and CII). They are combined with the published absorbing systems in Davies et al. (2023a) at the same redshift range to form of a sample of nine metal absorbers at z = 6.03 to 6.49. We identify eight galaxies within 1000 km s$^{-1}$ and 350 kpc around the absorbing gas from the ASPIRE spectroscopic data, with their redshifts secured by [OIII]($λλ$4959, 5007) doublets and H$β$ emission lines. Our spectral energy distribution fitting indicates that the absorbing galaxies have stellar mass ranging from 10$^{7.2}$ to 10$^{8.8}M_{\odot}$ and metallicity between 0.02 and 0.4 solar. Notably, the z = 6.2713 system in the J0305-3150 field resides in a galaxy overdensity region, which contains two (tentatively) merging galaxies within 350 kpc and seven galaxies within 1 Mpc. We measure the relative abundances of $α$ elements to iron ([$α$/Fe]) and find that the CGM gas in the most overdense region exhibits a lower [$α$/Fe] ratio. Our modeling of the galaxy's chemical abundance favors a top-heavy stellar initial mass function, and hints that we may be witnessing the contribution of the first generation Population III stars to the CGM at the end of reionization epoch.

astro-ph.GA↗
arXiv2023

Constraints on the Evolution of the Ionizing Background and Ionizing Photon Mean Free Path at the End of Reionization

The variations in Ly$α$ forest opacity observed at $z>5.3$ between lines of sight to different background quasars are too strong to be caused by fluctuations in the density field alone. The leading hypothesis for the cause of this excess variance is a late, ongoing reionization process at redshifts below six. Another model proposes strong ionizing background fluctuations coupled to a short, spatially varying mean free path of ionizing photons, without explicitly invoking incomplete reionization. With recent observations suggesting a short mean free path at $z\sim6$, and a dramatic improvement in $z>5$ Ly$α$ forest data quality, we revisit this latter possibility. Here we apply the likelihood-free inference technique of approximate Bayesian computation to jointly constrain the hydrogen photoionization rate $Γ_{\rm HI}$ and the mean free path of ionizing photons $λ_{\rm mfp}$ from the effective optical depth distributions at $z=5.0$-$6.1$ from XQR-30. We find that the observations are well-described by fluctuating mean free path models with average mean free paths that are consistent with the steep trend implied by independent measurements at $z\sim5$-$6$, with a concomitant rapid evolution of the photoionization rate.

astro-ph.CO↗
arXiv2023

Measurements of the $z > 5$ Lyman-$α$ forest flux auto-correlation functions from the extended XQR-30 data set

Recently, the Lyman-$α$ (Ly$α$) forest flux auto-correlation function has been shown to be sensitive to the mean free path of hydrogen-ionizing photons, $λ_{\text{mfp}}$, for simulations at $z \geq 5.4$. Measuring $λ_{\text{mfp}}$ at these redshifts will give vital information on the ending of reionization. Here we present the first observational measurements of the Ly$α$ forest flux auto-correlation functions in ten redshift bins from $5.1 \leq z \leq 6.0$. We use a sample of 35 quasar sightlines at $z > 5.7$ from the extended XQR-30 data set, this data has signal-to-noise ratios of $> 20$ per spectral pixel. We carefully account for systematic errors in continuum reconstruction, instrumentation, and contamination by damped Ly$α$ systems. With these measurements, we introduce software tools to generate auto-correlation function measurements from any simulation. For an initial comparison, we show our auto-correlation measurements with simulation models for recently measured $λ_{\text{mfp}}$ values and find good agreements. Further work in modeling and understanding the covariance matrices of the data is necessary to get robust measurements of $λ_{\text{mfp}}$ from this data.

astro-ph.CO↗