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Giulio Franzese

Publications and source records attributed to Giulio Franzese.

At least 19 recordsLinked to original sources

DIPHINE: Diffusion-based $Φ$-ID Neural Estimator

Uncovering the true informational architecture of real-world complex systems requires disentangling how their components uniquely store, redundantly share, and synergistically integrate information over time. Integrated Information Decomposition ($Φ$ID) is a framework for decomposing the information dynamics of multivariate systems into sixteen non-overlapping atoms that characterize redundant, unique, and synergistic modes of information storage, transfer, and integration. Existing methods to compute $Φ$ID are restricted to Gaussian or discrete systems, preventing its application to continuous non-Gaussian dynamical systems. We address this limitation by proposing DIPHINE (Diffusion-based $Φ$-ID Neural Estimator), the first neural estimator that leverages score-based diffusion models to jointly estimate all the mutual information terms required by $Φ$ID from a single amortized network, recovering the sixteen atoms through Möbius inversion. We provide a theoretical analysis of error propagation through the inversion, showing that the Jacobian of the mapping from mutual informations to atoms is integer-valued and that the synergy-to-synergy atom is provably the hardest to estimate. We demonstrate accurate recovery of ground-truth atoms on synthetic benchmarks, superior performance compared to established mutual information estimators, and the ability to extract physiologically interpretable information-dynamic structure on an application involving real data without any distributional assumptions.

cs.LG

From Atoms to Entropy: Optimal Noise Allocation for Diffusion Training in the Convex Regime

How should a diffusion model decide which noise levels to train on, and how much? Despite the importance of this choice, current noise schedules are based largely on heuristics or empirical tuning. Here, we develop a general statistical framework for studying asymptotically optimal noise-level allocation in diffusion training. Our first main result concerns the fully coupled regime, where information can spread between different time points. Under convexity or Polyak-Lojasiewicz-type assumptions, we show that the optimized training schedule admits an atomic minimizer, concentrated on finitely many noise levels. Our second main result specializes this framework to an idealized independent-learner regime, intended to model temporal specialization in neural networks. Under an additional feature-noise decoupling condition, a random-matrix analysis leads to an information-theoretic proxy: the decoupled sampling density is proportional to the square root of the generative entropy rate, the rate at which conditional entropy grows along the forward process. We test these predictions in controlled settings where the coupled objective can be optimized directly, including Dirac mixtures, low-dimensional manifolds, and MNIST. In these settings, the optimized schedules are consistently finite-support, while the smooth entropic proxy closely tracks the atomic optimum in neural-network models and breaks down mainly in the fully coupled parametric case, as the theory suggests. We then evaluate the entropic schedule in larger-scale experiments, where full schedule optimization is currently intractable. The results indicate that square-root entropy scheduling can substantially improve training efficiency on discrete domains and remains competitive with standard EDM-style heuristics on continuous images.

cs.LG

Towards Diverse and Comprehensive Benchmarks for Mutual Information Estimation

Mutual information (MI) estimation is a central problem in machine learning and statistics; however, existing benchmarks typically evaluate estimators on simplified, low-dimensional distributions, leaving their performance on complex, realistic data largely unexplored. We address this gap with a comprehensive benchmarking framework grounded in a unified copula-theoretic perspective that subsumes existing benchmarks as special cases. Within this framework, we propose two complementary families of tests: a copula-first family that systematically varies ground-truth MI, dimensionality, and marginal complexity using synthetic and flow-based transformations; and a marginals-first family that couples real-world image data with controlled dependency structures, extending the classic same-class-pairing paradigm. We use this suite to extensively evaluate three classes of estimators: non-parametric, discriminative, and generative. Contrary to prevailing assumptions, our results indicate that there is no universal winner: each category can systematically outperform all other estimators under specific setups. By analyzing these cases, we identify fundamental estimation barriers and propose new tests that more effectively stress these specific limitations. We share the open source code at https://github.com/VanessB/mutinfo.

cs.LG

Relative Entropy Estimation in Function Space: Theory and Applications to Trajectory Inference

Trajectory Inference (TI) seeks to recover latent dynamical processes from snapshot data, where only independent samples from time-indexed marginals are observed. In applications such as single-cell genomics, destructive measurements make path-space laws non-identifiable from finitely many marginals, leaving held-out marginal prediction as the dominant but limited evaluation protocol. We introduce a general framework for estimating the Kullback-Leibler divergence (KL) divergence between probability measures on function space, yielding a tractable, data-driven estimator that is scalable to realistic snapshot datasets. We validate the accuracy of our estimator on a benchmark suite, where the estimated functional KL closely matches the analytic KL. Applying this framework to synthetic and real scRNA-seq datasets, we show that current evaluation metrics often give inconsistent assessments, whereas path-space KL enables a coherent comparison of trajectory inference methods and exposes discrepancies in inferred dynamics, especially in regions with sparse or missing data. These results support functional KL as a principled criterion for evaluating trajectory inference under partial observability.

cs.LG

TENDE: Transfer Entropy Neural Diffusion Estimation

Transfer entropy measures directed information flow in time series, and it has become a fundamental quantity in applications spanning neuroscience, finance, and complex systems analysis. However, existing estimation methods suffer from the curse of dimensionality, require restrictive distributional assumptions, or need exponentially large datasets for reliable convergence. We address these limitations in the literature by proposing TENDE (Transfer Entropy Neural Diffusion Estimation), a novel approach that leverages score-based diffusion models to estimate transfer entropy through conditional mutual information. By learning score functions of the relevant conditional distributions, TENDE provides flexible, scalable estimation while making minimal assumptions about the underlying data-generating process. We demonstrate superior accuracy and robustness compared to existing neural estimators and other state-of-the-art approaches across synthetic benchmarks and real data.

cs.LG

Scaling Laws for Uncertainty in Deep Learning

Deep learning has recently revealed the existence of scaling laws, demonstrating that model performance follows predictable trends based on dataset and model sizes. Inspired by these findings and fascinating phenomena emerging in the over-parameterized regime, we examine a parallel direction: do similar scaling laws govern predictive uncertainties in deep learning? In identifiable parametric models, such scaling laws can be derived in a straightforward manner by treating model parameters in a Bayesian way. In this case, for example, we obtain $O(1/N)$ contraction rates for epistemic uncertainty with respect to the number of data $N$. However, in over-parameterized models, these guarantees do not hold, leading to largely unexplored behaviors. In this work, we empirically show the existence of scaling laws associated with various measures of predictive uncertainty with respect to dataset and model sizes. Through experiments on vision and language tasks, we observe such scaling laws for in- and out-of-distribution predictive uncertainty estimated through popular approximate Bayesian inference and ensemble methods. Besides the elegance of scaling laws and the practical utility of extrapolating uncertainties to larger data or models, this work provides strong evidence to dispel recurring skepticism against Bayesian approaches: "In many applications of deep learning we have so much data available: what do we need Bayes for?". Our findings show that "so much data" is typically not enough to make epistemic uncertainty negligible.

stat.ML

Improved Sampling Schedules for Discrete Diffusion Models

Discrete diffusion models have emerged as a powerful paradigm for generative modeling on sequence data; however, the information-theoretic principles governing their reverse processes remain significantly less understood than those of their continuous counterparts. In this work, we bridge this gap by analyzing the reverse process dynamics through the lens of thermodynamic entropy production. We propose the entropy production rate as a rigorous proxy for quantifying information generation, deriving as a byproduct a bound on the Wasserstein distance between intermediate states and the data distribution. Leveraging these insights, we introduce two novel sampling schedules that are uniformly spaced with respect to their corresponding physics-inspired metrics: the Entropic Discrete Schedule (EDS), which is defined by maintaining a constant rate of information gain, and the Wasserstein Discrete Schedule (WDS), which is defined by taking equal steps in terms of the Wasserstein distance. We empirically demonstrate that our proposed schedules significantly outperform state-of-the-art strategies across diverse application domains, including synthetic data, music notation, vision and language modeling, consistently achieving superior performance at a lower computational budget.

cs.LG

Learning to Match Unpaired Data with Minimum Entropy Coupling

Multimodal data is a precious asset enabling a variety of downstream tasks in machine learning. However, real-world data collected across different modalities is often not paired, which is a significant challenge to learn a joint distribution. A prominent approach to address the modality coupling problem is Minimum Entropy Coupling (MEC), which seeks to minimize the joint Entropy, while satisfying constraints on the marginals. Existing approaches to the MEC problem focus on finite, discrete distributions, limiting their application for cases involving continuous data. In this work, we propose a novel method to solve the continuous MEC problem, using well-known generative diffusion models that learn to approximate and minimize the joint Entropy through a cooperative scheme, while satisfying a relaxed version of the marginal constraints. We empirically demonstrate that our method, DDMEC, is general and can be easily used to address challenging tasks, including unsupervised single-cell multi-omics data alignment and unpaired image translation, outperforming specialized methods.

cs.LG

In Praise of Stubbornness: An Empirical Case for Cognitive-Dissonance Aware Continual Update of Knowledge in LLMs

Through systematic empirical investigation, we uncover a fundamental and concerning property of Large Language Models: while they can safely learn facts that don't contradict their knowledge, attempting to update facts with contradictory information triggers catastrophic corruption of unrelated knowledge. Unlike humans, who naturally resist contradictory information, these models indiscriminately accept contradictions, leading to devastating interference, destroying up to 80% of unrelated knowledge even when learning as few as 10-100 contradicting facts. To understand whether this interference could be mitigated through selective plasticity, we experiment with targeted network updates, distinguishing between previously used (stubborn) and rarely used (plastic) neurons. We uncover another asymmetry: while sparing frequently-used neurons significantly improves retention of existing knowledge for non-contradictory updates (98% vs 93% with standard updates), contradictory updates trigger catastrophic interference regardless of targeting strategy. This effect which persists across tested model scales (GPT-2 to GPT-J-6B), suggests a fundamental limitation in how neural networks handle contradictions. Finally, we demonstrate that contradictory information can be reliably detected (95%+ accuracy) using simple model features, offering a potential protective mechanism. These findings motivate new architectures that can, like humans, naturally resist contradictions rather than allowing destructive overwrites.

cs.CL

RFMI: Estimating Mutual Information on Rectified Flow for Text-to-Image Alignment

Rectified Flow (RF) models trained with a Flow matching framework have achieved state-of-the-art performance on Text-to-Image (T2I) conditional generation. Yet, multiple benchmarks show that synthetic images can still suffer from poor alignment with the prompt, i.e., images show wrong attribute binding, subject positioning, numeracy, etc. While the literature offers many methods to improve T2I alignment, they all consider only Diffusion Models, and require auxiliary datasets, scoring models, and linguistic analysis of the prompt. In this paper we aim to address these gaps. First, we introduce RFMI, a novel Mutual Information (MI) estimator for RF models that uses the pre-trained model itself for the MI estimation. Then, we investigate a self-supervised fine-tuning approach for T2I alignment based on RFMI that does not require auxiliary information other than the pre-trained model itself. Specifically, a fine-tuning set is constructed by selecting synthetic images generated from the pre-trained RF model and having high point-wise MI between images and prompts. Our experiments on MI estimation benchmarks demonstrate the validity of RFMI, and empirical fine-tuning on SD3.5-Medium confirms the effectiveness of RFMI for improving T2I alignment while maintaining image quality.

cs.CV

INFO-SEDD: Continuous Time Markov Chains as Scalable Information Metrics Estimators

Information-theoretic quantities play a crucial role in understanding non-linear relationships between random variables and are widely used across scientific disciplines. However, estimating these quantities remains an open problem, particularly in the case of high-dimensional discrete distributions. Current approaches typically rely on embedding discrete data into a continuous space and applying neural estimators originally designed for continuous distributions, a process that may not fully capture the discrete nature of the underlying data. We consider Continuous-Time Markov Chains (CTMCs), stochastic processes on discrete state-spaces which have gained popularity due to their generative modeling applications. In this work, we introduce INFO-SEDD, a novel method for estimating information-theoretic quantities of discrete data, including mutual information and entropy. Our approach requires the training of a single parametric model, offering significant computational and memory advantages. Additionally, it seamlessly integrates with pretrained networks, allowing for efficient reuse of pretrained generative models. To evaluate our approach, we construct a challenging synthetic benchmark. Our experiments demonstrate that INFO-SEDD is robust and outperforms neural competitors that rely on embedding techniques. Moreover, we validate our method on a real-world task: estimating the entropy of an Ising model. Overall, INFO-SEDD outperforms competing methods and shows scalability to high-dimensional scenarios, paving the way for new applications where estimating MI between discrete distribution is the focus. The promising results in this complex, high-dimensional scenario highlight INFO-SEDD as a powerful new estimator in the toolkit for information-theoretical analysis.

cs.LG

Information Theoretic Text-to-Image Alignment

Diffusion models for Text-to-Image (T2I) conditional generation have recently achieved tremendous success. Yet, aligning these models with user's intentions still involves a laborious trial-and-error process, and this challenging alignment problem has attracted considerable attention from the research community. In this work, instead of relying on fine-grained linguistic analyses of prompts, human annotation, or auxiliary vision-language models, we use Mutual Information (MI) to guide model alignment. In brief, our method uses self-supervised fine-tuning and relies on a point-wise (MI) estimation between prompts and images to create a synthetic fine-tuning set for improving model alignment. Our analysis indicates that our method is superior to the state-of-the-art, yet it only requires the pre-trained denoising network of the T2I model itself to estimate MI, and a simple fine-tuning strategy that improves alignment while maintaining image quality. Code available at https://github.com/Chao0511/mitune.

cs.LG

Latent Abstractions in Generative Diffusion Models

In this work we study how diffusion-based generative models produce high-dimensional data, such as an image, by implicitly relying on a manifestation of a low-dimensional set of latent abstractions, that guide the generative process. We present a novel theoretical framework that extends NLF, and that offers a unique perspective on SDE-based generative models. The development of our theory relies on a novel formulation of the joint (state and measurement) dynamics, and an information-theoretic measure of the influence of the system state on the measurement process. According to our theory, diffusion models can be cast as a system of SDE, describing a non-linear filter in which the evolution of unobservable latent abstractions steers the dynamics of an observable measurement process (corresponding to the generative pathways). In addition, we present an empirical study to validate our theory and previous empirical results on the emergence of latent abstractions at different stages of the generative process.

cs.LG

S$Ω$I: Score-based O-INFORMATION Estimation

The analysis of scientific data and complex multivariate systems requires information quantities that capture relationships among multiple random variables. Recently, new information-theoretic measures have been developed to overcome the shortcomings of classical ones, such as mutual information, that are restricted to considering pairwise interactions. Among them, the concept of information synergy and redundancy is crucial for understanding the high-order dependencies between variables. One of the most prominent and versatile measures based on this concept is O-information, which provides a clear and scalable way to quantify the synergy-redundancy balance in multivariate systems. However, its practical application is limited to simplified cases. In this work, we introduce S$Ω$I, which allows for the first time to compute O-information without restrictive assumptions about the system. Our experiments validate our approach on synthetic data, and demonstrate the effectiveness of S$Ω$I in the context of a real-world use case.

cs.LG

MINDE: Mutual Information Neural Diffusion Estimation

In this work we present a new method for the estimation of Mutual Information (MI) between random variables. Our approach is based on an original interpretation of the Girsanov theorem, which allows us to use score-based diffusion models to estimate the Kullback Leibler divergence between two densities as a difference between their score functions. As a by-product, our method also enables the estimation of the entropy of random variables. Armed with such building blocks, we present a general recipe to measure MI, which unfolds in two directions: one uses conditional diffusion process, whereas the other uses joint diffusion processes that allow simultaneous modelling of two random variables. Our results, which derive from a thorough experimental protocol over all the variants of our approach, indicate that our method is more accurate than the main alternatives from the literature, especially for challenging distributions. Furthermore, our methods pass MI self-consistency tests, including data processing and additivity under independence, which instead are a pain-point of existing methods.

cs.LG

ADROIT6G DAI-driven Open and Programmable Architecture for 6G Networks

In the upcoming 6G era, mobile networks must deal with more challenging applications (e.g., holographic telepresence and immersive communication) and meet far more stringent application requirements stemming along the edge-cloud continuum. These new applications will create an elevated level of expectations on performance, reliability, ubiquity, trustworthiness, security, openness, and sustainability, pushing the boundaries of innovation and driving transformational change across the architecture of future mobile networks. Towards this end, ADROIT6G proposes a set of disruptive innovations with a clear vision on setting a 6G network architecture that can be tailored to the requirements of innovative applications and match the ambitious KPIs set for 6G networks. More specifically, the key transformations that ADROIT6G considers essential to 6G network evolution are: i) AI/ML-powered optimisations across the network, exploring solutions in the "Distributed Artificial Intelligence (DAI)" domain for high performance and automation; ii) Transforming to fully cloud-native network software, which can be implemented across various edge-cloud platforms, with security built integrally into the network user plan; and iii) Software driven, zero-touch operations and ultimately automation of every aspect of the network and the services it delivers.

cs.NI

One-Line-of-Code Data Mollification Improves Optimization of Likelihood-based Generative Models

Generative Models (GMs) have attracted considerable attention due to their tremendous success in various domains, such as computer vision where they are capable to generate impressive realistic-looking images. Likelihood-based GMs are attractive due to the possibility to generate new data by a single model evaluation. However, they typically achieve lower sample quality compared to state-of-the-art score-based diffusion models (DMs). This paper provides a significant step in the direction of addressing this limitation. The idea is to borrow one of the strengths of score-based DMs, which is the ability to perform accurate density estimation in low-density regions and to address manifold overfitting by means of data mollification. We connect data mollification through the addition of Gaussian noise to Gaussian homotopy, which is a well-known technique to improve optimization. Data mollification can be implemented by adding one line of code in the optimization loop, and we demonstrate that this provides a boost in generation quality of likelihood-based GMs, without computational overheads. We report results on image data sets with popular likelihood-based GMs, including variants of variational autoencoders and normalizing flows, showing large improvements in FID score.

cs.LG

Continuous-Time Functional Diffusion Processes

We introduce Functional Diffusion Processes (FDPs), which generalize score-based diffusion models to infinite-dimensional function spaces. FDPs require a new mathematical framework to describe the forward and backward dynamics, and several extensions to derive practical training objectives. These include infinite-dimensional versions of Girsanov theorem, in order to be able to compute an ELBO, and of the sampling theorem, in order to guarantee that functional evaluations in a countable set of points are equivalent to infinite-dimensional functions. We use FDPs to build a new breed of generative models in function spaces, which do not require specialized network architectures, and that can work with any kind of continuous data. Our results on real data show that FDPs achieve high-quality image generation, using a simple MLP architecture with orders of magnitude fewer parameters than existing diffusion models.

cs.LG