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Gokul Upadhyay

Publications and source records attributed to Gokul Upadhyay.

2 recordsLinked to original sources

Aggressive Phase Separation in Dense Mixtures of Passive and Active Particles

Using Vicsek-like self-propulsion rule, we study kinetics of liquid-liquid phase separation in mixtures of passive and active particles. For evolutions following temperature quenches of homogeneous configurations to the immiscible region of the phase diagram, we identify a remarkably strong dependence of the domain growth exponent on the choice of final state point. The singular dependence is indicative of the possibility of even an exponentially fast growth for suitable choices of system parameters. This striking observation, supported by finite-size scaling and other advanced analyses, is despite the fact that the overall mixture density is quite high that risks congestion with the prospect of slowing down particle transport. From flocking in pure biological systems to robotic swarming, these results are of much practical relevance. Theoretical pictures suitable for interpreting such high growth rates are discussed. In this regard, we discuss coarsening in the velocity field as well that describes how the density field coarsening follows the latter.

cond-mat.soft

Packing and ejection dynamics of polymers: Role of confinement, polymer stiffness and activity

The translocation of biopolymers, such as DNA and proteins, across cellular or nuclear membranes is essential for numerous biological processes. The translocation dynamics are influenced by the properties of the polymers, such as polymer stiffness, and the geometry of the capsid. In our study, we aim to investigate the impact of polymer stiffness, activity, and different capsid geometries on the packing and ejection dynamics of both passive and active polymers. We employ Langevin dynamics simulations for a systematic investigation. We observe that flexible polymers exhibit packing times that are faster than those of their semi-flexible counterparts. Interestingly, for large polymers compared to the capsid size, sphere facilitates faster packing and unpacking compared to ellipsoid, mimicking the cell nucleus and suggesting a geometrical advantage for biopolymer translocation. In summary, we observe that increasing activity accelerates both the packing and ejection processes for both flexible and semi-flexible polymers. However, the effect is significantly more pronounced for semi-flexible polymers, highlighting the crucial role of polymer flexibility in these dynamics. These findings deepen our understanding of the intricate interplay between polymer flexibility, capsid geometry, and activity, providing valuable insight into the dynamics of polymer packing and ejection processes.

cond-mat.soft