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Goro Nishimura

Publications and source records attributed to Goro Nishimura.

4 recordsLinked to original sources
arXiv2025

Direct inversion scheme of time-domain fluorescence diffuse optical tomography by asymptotic analysis of peak time

This paper proposes a direct inversion scheme for fluorescence diffuse optical tomography (FDOT) to reconstruct the location of a point target using the measured peak time of the temporal response functions. A sphere is defined for the target, with its radius determined by the peak time, indicating that the target lies on the sphere. By constructing a tetrahedron with edges determined by the radii, we identify the location of the target as the vertex of the tetrahedron. Asymptotically, we derive the relationship between the radius of the sphere and the peak time. Several numerical tests are implemented to demonstrate the accuracy and performance of the asymptotic relationship and the inversion scheme.

math.AP↗
arXiv2024

Approximate peak time to time-domain fluorescence diffuse optical tomography for nonzero fluorescence lifetime

This paper concerns an inverse problem for fluorescence diffuse optical tomography (FDOT) reconstructing locations of multiple point targets from the measured temporal response functions. The targets are multiple fluorescent point objects with a nonzero fluorescence lifetime at unknown locations. Peak time, when the temporal response function of the fluorescence reaches its maximum, is a robust parameter of the temporal response function in FDOT because it is most less suffered by the artifacts, such as noise, and is easily determined by experiments. We derive an approximate peak time equation based on asymptotic analysis in an explicit way in the case of nonzero fluorescence lifetime when there are single and multiple point targets. The performance of the approximation is numerically verified. Then, we develop a bisection algorithm to reconstruct the location of a single point target from the algorithm proposed in [4] for the case of zero fluorescence lifetime. Moreover, we propose a boundary-scan algorithm for the reconstruction of locations of multiple point targets. Finally, several numerical experiments are implemented to show the efficiency and robustness of the addressed algorithms.

math.NA↗
arXiv2021

Expression of the peak time for time-domain boundary measurements in diffuse light

Light propagation through diffusive media can be described by the diffusion equation in a space-time domain. Further, fluorescence can be described by a system of coupled diffusion equations. This paper analyzes time-domain measurements, which measure the temporal point-spread function (TPSF), at a boundary of such diffusive media with a given source and detector. We focus on the temporal position of the TPSF maximum, which we refer to as the peak time. Although some unique properties of solutions of this system have been numerically studied, we give a mathematical analysis of peak time, providing proof of the existence, uniqueness, and the explicit expression of the peak time. We clearly show the relationship between the peak time and the object position in a medium.

cs.CE↗