Gowtham Reddy N | Searcharxiv

arXiv2026

A Hybrid Gaze-Motor Imagery BCI Framework for Effective Decision Communication

Non-invasive brain-computer interfaces (BCIs) and eye-tracking technologies offer promising communication pathways; however, motor imagery (MI)-based BCIs often suffer from low discriminability and high inter-subject variability. To mitigate these issues, this study investigates the impact of visual fixation on neural response stability in both standalone MI and hybrid MI-eye tracking systems. We then propose a novel asynchronous hybrid paradigm that streamlines user intent by utilising eye-tracking for direct selection, followed by MI-based confirmation, significantly reducing the operational steps required by conventional systems. The paradigm was evaluated with 15 healthy participants using a 16-channel EEG system. Results show that MI-related information is predominantly localised within motor cortex regions, with limited-channel configurations (SVM: 0.58) achieving performance comparable to full-montage setups (SVM: 0.54). The hybrid MI paradigm further outperforms conventional MI, achieving up to 100% accuracy with greater robustness across all channel configurations. Our findings indicate that visual fixation enhances neural response stability, while integrating eye-tracking with MI enables the development of reliable, scalable multi-command BCI systems suitable for real-world applications.

cs.HC↗

arXiv2026

An Attention-Based Framework for Alzheimers Disease Classification Using Resting-State fMRI

Accurate identification of Alzheimers disease (AD) using resting-state functional magnetic resonance imaging (rs-fMRI) remains challenging due to the high dimensionality, noise, and complex inter-regional dependencies inherent in functional brain connectivity, which limit the effectiveness of traditional approaches based on handcrafted connectivity features or conventional machine learning models. In this work, we present an attention-based deep learning framework for Alzheimers disease classification that operates directly on rs-fMRI functional connectivity matrices by treating brain regions as tokens and employing a Transformer-inspired self-attention mechanism to model long-range and global functional dependencies across distributed brain networks. The proposed framework learns discriminative functional representations without reliance on manual feature engineering and is evaluated on a longitudinal cohort from the Alzheimers Disease Neuroimaging Initiative (ADNI) comprising cognitively normal and Alzheimers disease subjects with multiple visits. A subject-wise evaluation protocol is adopted to prevent information leakage across visits, and class-weighted optimization is incorporated to address mild class imbalance. Experimental results for binary AD versus cognitively normal classification demonstrate that the proposed attention- based rs-fMRI model achieves an accuracy of 88.95% and a ROC-AUC of 0.90, along with a favorable precision-recall balance, highlighting the effectiveness of self-attention-driven functional connectivity modeling as a robust and interpretable approach for Alzheimers disease detection using resting-state fMRI.

eess.IV↗