arXiv subjects

Graham Wright

Publications and source records attributed to Graham Wright.

4 recordsLinked to original sources

arXiv2026

The MYOSAIQ Challenge: Myocardial Segmentation with Automated Infarct Quantification

Late gadolinium enhancement (LGE) cardiac magnetic resonance (MR) imaging is the modality of choice to assess myocardial infarction (MI) lesions. Nowadays MI volume quantification is not performed routinely in clinical practice. Numerous deep learning (DL) methods have been developed to automate the segmentation of the myocardium and infarct regions. However, most studies rely on relatively small datasets which typically undergo pre-processing steps to standardize images and focus on a specific phase of myocardial infarction following reperfusion therapy. These limitations have impeded the development of models that are generalizable across diverse conditions and thus suitable for routine clinical use. To advance research and establish benchmarks in generalizable learning for myocardial infarct quantification, this paper presents findings from the Myocardial Segmentation with Automated Infarct Quantification (MYOSAIQ) challenge. The dataset set up for the challenge combines 439 CMR volumes from two multicenter clinical trials, with representative data acquired in acute and chronic phases after acute MI. Data were acquired in 16 centers using MRI scanners from three different vendors. Six teams participated until the end of the challenge, employing various baseline models, data augmentation techniques, and confidence strategies. To enhance the significance of this study, we compare the challengers' results with those of fine-tuned foundation models. Our results indicate that well-designed UNet-based techniques outperform fully automatic foundation models for LGE MR segmentation. While the best methods achieve high-quality and stable delineations of the left ventricle and myocardium under various conditions, they remain improvable in accurately segmenting infarct regions.

eess.IV↗

arXiv2023

Simulation-Driven Automated End-to-End Test and Oracle Inference

This is the first work to report on inferential testing at scale in industry. Specifically, it reports the experience of automated testing of integrity systems at Meta. We built an internal tool called ALPACAS for automated inference of end-to-end integrity tests. Integrity tests are designed to keep users safe online by checking that interventions take place when harmful behaviour occurs on a platform. ALPACAS infers not only the test input, but also the oracle, by observing production interventions to prevent harmful behaviour. This approach allows Meta to automate the process of generating integrity tests for its platforms, such as Facebook and Instagram, which consist of hundreds of millions of lines of production code. We outline the design and deployment of ALPACAS, and report results for its coverage, number of tests produced at each stage of the test inference process, and their pass rates. Specifically, we demonstrate that using ALPACAS significantly improves coverage from a manual test design for the particular aspect of integrity end-to-end testing it was applied to. Further, from a pool of 3 million data points, ALPACAS automatically yields 39 production-ready end-to-end integrity tests. We also report that the ALPACAS-inferred test suite enjoys exceptionally low flakiness for end-to-end testing with its average in-production pass rate of 99.84%.

cs.SE↗

arXiv2020

Estimating Uncertainty in Neural Networks for Cardiac MRI Segmentation: A Benchmark Study

Objective: Convolutional neural networks (CNNs) have demonstrated promise in automated cardiac magnetic resonance image segmentation. However, when using CNNs in a large real-world dataset, it is important to quantify segmentation uncertainty and identify segmentations which could be problematic. In this work, we performed a systematic study of Bayesian and non-Bayesian methods for estimating uncertainty in segmentation neural networks. Methods: We evaluated Bayes by Backprop, Monte Carlo Dropout, Deep Ensembles, and Stochastic Segmentation Networks in terms of segmentation accuracy, probability calibration, uncertainty on out-of-distribution images, and segmentation quality control. Results: We observed that Deep Ensembles outperformed the other methods except for images with heavy noise and blurring distortions. We showed that Bayes by Backprop is more robust to noise distortions while Stochastic Segmentation Networks are more resistant to blurring distortions. For segmentation quality control, we showed that segmentation uncertainty is correlated with segmentation accuracy for all the methods. With the incorporation of uncertainty estimates, we were able to reduce the percentage of poor segmentation to 5% by flagging 31--48% of the most uncertain segmentations for manual review, substantially lower than random review without using neural network uncertainty (reviewing 75--78% of all images). Conclusion: This work provides a comprehensive evaluation of uncertainty estimation methods and showed that Deep Ensembles outperformed other methods in most cases. Significance: Neural network uncertainty measures can help identify potentially inaccurate segmentations and alert users for manual review.

eess.IV↗

arXiv2016

Credibility and Dynamics of Collective Attention

Today, social media provide the means by which billions of people experience news and events happening around the world. However, the absence of traditional journalistic gatekeeping allows information to flow unencumbered through these platforms, often raising questions of veracity and credibility of the reported information. Here we ask: How do the dynamics of collective attention directed toward an event reported on social media vary with its perceived credibility? By examining the first large-scale, systematically tracked credibility database of public Twitter messages (47M messages corresponding to 1,138 real-world events over a span of three months), we established a relationship between the temporal dynamics of events reported on social media and their associated level of credibility judgments. Representing collective attention by the aggregate temporal signatures of an event reportage, we found that the amount of continued attention focused on an event provides information about its associated levels of perceived credibility. Events exhibiting sustained, intermittent bursts of attention were found to be associated with lower levels of perceived credibility. In other words, as more people showed interest during moments of transient collective attention, the associated uncertainty surrounding these events also increased.

cs.SI↗