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Gregor Leech

Publications and source records attributed to Gregor Leech.

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Three phases of odd robotic active matter

Nonreciprocal interactions in active matter are known to generate exotic mechanical behaviors such as odd elasticity and odd viscosity. However, these phenomena have largely been studied in isolation, raising a fundamental question: Is there a single system that embodies these distinct regimes of odd matter and can transition between phases, establishing a unified phase diagram for nonreciprocal active matter? To address this, we introduce a tunable robotic active matter platform, the Magnetomechanically Augmented Spinning roBotic (MASBot) collective, in which particle-level control of chirality, activity, and pairwise interactions enables access to distinct phases of odd matter. By continuously increasing repulsive forces relative to attractive and transverse forces, we experimentally map a transition from an odd elastic crystal to an odd viscous liquid, and then to a chiral active gas. We find that this latter phase forms a non-space-filling, nonreciprocal active gas stabilized by long-range hydrodynamic attractive forces, whose statistical signatures are consistent with those of a two-dimensional self-gravitating point vortex gas. Within these phases, adjusting spinning frequency and introducing spatially patterned activity allows us to fine-tune odd mechanical responses and tailor power spectra. Further polar and rotational symmetry breaking at the particle scale leads to novel emergent states such as phase separation and collective translation. Together, our system provides a fundamental experimental testbed for nonequilibrium physics and establishes a blueprint for treating robotic swarms as programmable states of matter, enabling functions that range from resilient structures to adaptive swarm reconfiguration.

cond-mat.soft

Timed material self-assembly controlled by circadian clock proteins

Active biological molecules present a powerful, yet largely untapped, opportunity to impart autonomous regulation to materials. Because these systems can function robustly to regulate when and where chemical reactions occur, they have the ability to bring complex, life-like behavior to synthetic materials. Here, we achieve this design feat by using functionalized circadian clock proteins, KaiB and KaiC, to engineer time-dependent crosslinking of colloids. The resulting material self-assembles with programmable kinetics, producing macroscopic changes in material properties, via molecular assembly of KaiB-KaiC complexes. We show that colloid crosslinking depends strictly on the phosphorylation state of KaiC, with kinetics that are synced with KaiB-KaiC complexing. Our microscopic image analyses and computational models indicate that the stability of colloidal super-structures depends sensitively on the number of Kai complexes per colloid connection. Consistent with our model predictions, a high concentration stabilizes the material against dissolution after a robust self-assembly phase, while a low concentration allows circadian oscillation of material structure. This work introduces the concept of harnessing biological timers to control synthetic materials; and, more generally, opens the door to using protein-based reaction networks to endow synthetic systems with life-like functional properties.

cond-mat.soft

Active Cytoskeletal Composites Display Emergent Tunable Contractility and Restructuring

The cytoskeleton is a model active matter system that controls diverse cellular processes from division to motility. While both active actomyosin dynamics and actin-microtubule interactions are key to the cytoskeleton's versatility and adaptability, an understanding of their interplay is lacking. Here, we couple microscale experiments with mechanistic modeling to elucidate how connectivity, rigidity, and force-generation affect emergent material properties in in vitro composites of actin, tubulin, and myosin. We use time-resolved differential dynamic microscopy and spatial image autocorrelation to show that ballistic contraction occurs in composites with sufficient flexibility and motor density, but that a critical fraction of microtubules is necessary to sustain controlled dynamics. Our active double-network models reveal that percolated actomyosin networks are essential for contraction, but that networks with comparable actin and microtubule densities can uniquely resist mechanical stresses while simultaneously supporting substantial restructuring. Our findings provide a much-needed blueprint for designing cytoskeleton-inspired materials that couple tunability with resilience and adaptability.

cond-mat.soft