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Guang Cheng

Publications and source records attributed to Guang Cheng.

At least 181 records · Page 10Linked to original sources

Non-asymptotic theory for nonparametric testing

We consider nonparametric testing in a non-asymptotic framework. Our statistical guarantees are exact in the sense that Type I and II errors are controlled for any finite sample size. Meanwhile, one proposed test is shown to achieve minimax optimality in the asymptotic sense. An important consequence of this non-asymptotic theory is a new and practically useful formula for selecting the optimal smoothing parameter in nonparametric testing. The leading example in this paper is smoothing spline models under Gaussian errors. The results obtained therein can be further generalized to the kernel ridge regression framework under possibly non-Gaussian errors. Simulations demonstrate that our proposed test improves over the conventional asymptotic test when sample size is small to moderate.

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Stability Enhanced Large-Margin Classifier Selection

Stability is an important aspect of a classification procedure because unstable predictions can potentially reduce users' trust in a classification system and also harm the reproducibility of scientific conclusions. The major goal of our work is to introduce a novel concept of classification instability, i.e., decision boundary instability (DBI), and incorporate it with the generalization error (GE) as a standard for selecting the most accurate and stable classifier. Specifically, we implement a two-stage algorithm: (i) initially select a subset of classifiers whose estimated GEs are not significantly different from the minimal estimated GE among all the candidate classifiers; (ii) the optimal classifier is chosen as the one achieving the minimal DBI among the subset selected in stage (i). This general selection principle applies to both linear and nonlinear classifiers. Large-margin classifiers are used as a prototypical example to illustrate the above idea. Our selection method is shown to be consistent in the sense that the optimal classifier simultaneously achieves the minimal GE and the minimal DBI. Various simulations and real examples further demonstrate the advantage of our method over several alternative approaches.

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Embracing the Blessing of Dimensionality in Factor Models

Factor modeling is an essential tool for exploring intrinsic dependence structures among high-dimensional random variables. Much progress has been made for estimating the covariance matrix from a high-dimensional factor model. However, the blessing of dimensionality has not yet been fully embraced in the literature: much of the available data is often ignored in constructing covariance matrix estimates. If our goal is to accurately estimate a covariance matrix of a set of targeted variables, shall we employ additional data, which are beyond the variables of interest, in the estimation? In this paper, we provide sufficient conditions for an affirmative answer, and further quantify its gain in terms of Fisher information and convergence rate. In fact, even an oracle-like result (as if all the factors were known) can be achieved when a sufficiently large number of variables is used. The idea of utilizing data as much as possible brings computational challenges. A divide-and-conquer algorithm is thus proposed to alleviate the computational burden, and also shown not to sacrifice any statistical accuracy in comparison with a pooled analysis. Simulation studies further confirm our advocacy for the use of full data, and demonstrate the effectiveness of the above algorithm. Our proposal is applied to a microarray data example that shows empirical benefits of using more data.

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Provable Sparse Tensor Decomposition

We propose a novel sparse tensor decomposition method, namely Tensor Truncated Power (TTP) method, that incorporates variable selection into the estimation of decomposition components. The sparsity is achieved via an efficient truncation step embedded in the tensor power iteration. Our method applies to a broad family of high dimensional latent variable models, including high dimensional Gaussian mixture and mixtures of sparse regressions. A thorough theoretical investigation is further conducted. In particular, we show that the final decomposition estimator is guaranteed to achieve a local statistical rate, and further strengthen it to the global statistical rate by introducing a proper initialization procedure. In high dimensional regimes, the obtained statistical rate significantly improves those shown in the existing non-sparse decomposition methods. The empirical advantages of TTP are confirmed in extensive simulated results and two real applications of click-through rate prediction and high-dimensional gene clustering.

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Simultaneous Inference for High-dimensional Linear Models

This paper proposes a bootstrap-assisted procedure to conduct simultaneous inference for high dimensional sparse linear models based on the recent de-sparsifying Lasso estimator (van de Geer et al. 2014). Our procedure allows the dimension of the parameter vector of interest to be exponentially larger than sample size, and it automatically accounts for the dependence within the de-sparsifying Lasso estimator. Moreover, our simultaneous testing method can be naturally coupled with the margin screening (Fan and Lv 2008) to enhance its power in sparse testing with a reduced computational cost, or with the step-down method (Romano and Wolf 2005) to provide a strong control for the family-wise error rate. In theory, we prove that our simultaneous testing procedure asymptotically achieves the pre-specified significance level, and enjoys certain optimality in terms of its power even when the model errors are non-Gaussian. Our general theory is also useful in studying the support recovery problem. To broaden the applicability, we further extend our main results to generalized linear models with convex loss functions. The effectiveness of our methods is demonstrated via simulation studies.

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A Partially Linear Framework for Massive Heterogeneous Data

We consider a partially linear framework for modelling massive heterogeneous data. The major goal is to extract common features across all sub-populations while exploring heterogeneity of each sub-population. In particular, we propose an aggregation type estimator for the commonality parameter that possesses the (non-asymptotic) minimax optimal bound and asymptotic distribution as if there were no heterogeneity. This oracular result holds when the number of sub-populations does not grow too fast. A plug-in estimator for the heterogeneity parameter is further constructed, and shown to possess the asymptotic distribution as if the commonality information were available. We also test the heterogeneity among a large number of sub-populations. All the above results require to regularize each sub-estimation as though it had the entire sample size. Our general theory applies to the divide-and-conquer approach that is often used to deal with massive homogeneous data. A technical by-product of this paper is the statistical inferences for the general kernel ridge regression. Thorough numerical results are also provided to back up our theory.

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Nonparametric Heterogeneity Testing For Massive Data

A massive dataset often consists of a growing number of (potentially) heterogeneous sub-populations. This paper is concerned about testing various forms of heterogeneity arising from massive data. In a general nonparametric framework, a set of testing procedures are designed to accommodate a growing number of sub-populations, denoted as $s$, with computational feasibility. In theory, their null limit distributions are derived as being nearly Chi-square with diverging degrees of freedom as long as $s$ does not grow too fast. Interestingly, we find that a lower bound on $s$ needs to be set for obtaining a sufficiently powerful testing result, so-called "blessing of aggregation." As a by-produc, a type of homogeneity testing is also proposed with a test statistic being aggregated over all sub-populations. Numerical results are presented to support our theory.

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Stabilized Nearest Neighbor Classifier and Its Statistical Properties

The stability of statistical analysis is an important indicator for reproducibility, which is one main principle of scientific method. It entails that similar statistical conclusions can be reached based on independent samples from the same underlying population. In this paper, we introduce a general measure of classification instability (CIS) to quantify the sampling variability of the prediction made by a classification method. Interestingly, the asymptotic CIS of any weighted nearest neighbor classifier turns out to be proportional to the Euclidean norm of its weight vector. Based on this concise form, we propose a stabilized nearest neighbor (SNN) classifier, which distinguishes itself from other nearest neighbor classifiers, by taking the stability into consideration. In theory, we prove that SNN attains the minimax optimal convergence rate in risk, and a sharp convergence rate in CIS. The latter rate result is established for general plug-in classifiers under a low-noise condition. Extensive simulated and real examples demonstrate that SNN achieves a considerable improvement in CIS over existing nearest neighbor classifiers, with comparable classification accuracy. We implement the algorithm in a publicly available R package snn.

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Nonparametric inference in generalized functional linear models

We propose a roughness regularization approach in making nonparametric inference for generalized functional linear models. In a reproducing kernel Hilbert space framework, we construct asymptotically valid confidence intervals for regression mean, prediction intervals for future response and various statistical procedures for hypothesis testing. In particular, one procedure for testing global behaviors of the slope function is adaptive to the smoothness of the slope function and to the structure of the predictors. As a by-product, a new type of Wilks phenomenon [Ann. Math. Stat. 9 (1938) 60-62; Ann. Statist. 29 (2001) 153-193] is discovered when testing the functional linear models. Despite the generality, our inference procedures are easy to implement. Numerical examples are provided to demonstrate the empirical advantages over the competing methods. A collection of technical tools such as integro-differential equation techniques [Trans. Amer. Math. Soc. (1927) 29 755-800; Trans. Amer. Math. Soc. (1928) 30 453-471; Trans. Amer. Math. Soc. (1930) 32 860-868], Stein's method [Ann. Statist. 41 (2013) 2786-2819] [Stein, Approximate Computation of Expectations (1986) IMS] and functional Bahadur representation [Ann. Statist. 41 (2013) 2608-2638] are employed in this paper.

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Active Clinical Trials for Personalized Medicine

Individualized treatment rules (ITRs) tailor treatments according to individual patient characteristics. They can significantly improve patient care and are thus becoming increasingly popular. The data collected during randomized clinical trials are often used to estimate the optimal ITRs. However, these trials are generally expensive to run, and, moreover, they are not designed to efficiently estimate ITRs. In this paper, we propose a cost-effective estimation method from an active learning perspective. In particular, our method recruits only the "most informative" patients (in terms of learning the optimal ITRs) from an ongoing clinical trial. Simulation studies and real-data examples show that our active clinical trial method significantly improves on competing methods. We derive risk bounds and show that they support these observed empirical advantages.

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Joint asymptotics for semi-nonparametric regression models with partially linear structure

We consider a joint asymptotic framework for studying semi-nonparametric regression models where (finite-dimensional) Euclidean parameters and (infinite-dimensional) functional parameters are both of interest. The class of models in consideration share a partially linear structure and are estimated in two general contexts: (i) quasi-likelihood and (ii) true likelihood. We first show that the Euclidean estimator and (pointwise) functional estimator, which are re-scaled at different rates, jointly converge to a zero-mean Gaussian vector. This weak convergence result reveals a surprising joint asymptotics phenomenon: these two estimators are asymptotically independent. A major goal of this paper is to gain first-hand insights into the above phenomenon. Moreover, a likelihood ratio testing is proposed for a set of joint local hypotheses, where a new version of the Wilks phenomenon [Ann. Math. Stat. 9 (1938) 60-62; Ann. Statist. 1 (2001) 153-193] is unveiled. A novel technical tool, called a joint Bahadur representation, is developed for studying these joint asymptotics results.

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Semiparametric Bernstein-von Mises Theorem: Second Order Studies

The major goal of this paper is to study the second order frequentist properties of the marginal posterior distribution of the parametric component in semiparametric Bayesian models, in particular, a second order semiparametric Bernstein-von Mises (BvM) Theorem. Our first contribution is to discover an interesting interference phenomenon between Bayesian estimation and frequentist inferential accuracy: more accurate Bayesian estimation on the nuisance function leads to higher frequentist inferential accuracy on the parametric component. As the second contribution, we propose a new class of dependent priors under which Bayesian inference procedures for the parametric component are not only efficient but also adaptive (w.r.t. the smoothness of nonparametric component) up to the second order frequentist validity. However, commonly used independent priors may even fail to produce a desirable root-n contraction rate for the parametric component in this adaptive case unless some stringent assumption is imposed. Three important classes of semiparametric models are examined, and extensive simulations are also provided.

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Optimal Bayesian estimation in random covariate design with a rescaled Gaussian process prior

In Bayesian nonparametric models, Gaussian processes provide a popular prior choice for regression function estimation. Existing literature on the theoretical investigation of the resulting posterior distribution almost exclusively assume a fixed design for covariates. The only random design result we are aware of (van der Vaart & van Zanten, 2011) assumes the assigned Gaussian process to be supported on the smoothness class specified by the true function with probability one. This is a fairly restrictive assumption as it essentially rules out the Gaussian process prior with a squared exponential kernel when modeling rougher functions. In this article, we show that an appropriate rescaling of the above Gaussian process leads to a rate-optimal posterior distribution even when the covariates are independently realized from a known density on a compact set. The proofs are based on deriving sharp concentration inequalities for frequentist kernel estimators; the results might be of independent interest.

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Moment Consistency of the Exchangeably Weighted Bootstrap for Semiparametric M-Estimation

The bootstrap variance estimate is widely used in semiparametric inferences. However, its theoretical validity is a well known open problem. In this paper, we provide a {\em first} theoretical study on the bootstrap moment estimates in semiparametric models. Specifically, we establish the bootstrap moment consistency of the Euclidean parameter which immediately implies the consistency of $t$-type bootstrap confidence set. It is worth pointing out that the only additional cost to achieve the bootstrap moment consistency in contrast with the distribution consistency is to simply strengthen the $L_1$ maximal inequality condition required in the latter to the $L_p$ maximal inequality condition for $p\geq 1$. The general $L_p$ multiplier inequality developed in this paper is also of independent interest. These general conclusions hold for the bootstrap methods with exchangeable bootstrap weights, e.g., nonparametric bootstrap and Bayesian bootstrap. Our general theory is illustrated in the celebrated Cox regression model.

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Bootstrapping High Dimensional Time Series

This article studies bootstrap inference for high dimensional weakly dependent time series in a general framework of approximately linear statistics. The following high dimensional applications are covered: (1) uniform confidence band for mean vector; (2) specification testing on the second order property of time series such as white noise testing and bandedness testing of covariance matrix; (3) specification testing on the spectral property of time series. In theory, we first derive a Gaussian approximation result for the maximum of a sum of weakly dependent vectors, where the dimension of the vectors is allowed to be exponentially larger than the sample size. In particular, we illustrate an interesting interplay between dependence and dimensionality, and also discuss one type of "dimension free" dependence structure. We further propose a blockwise multiplier (wild) bootstrap that works for time series with unknown autocovariance structure. These distributional approximation errors, which are finite sample valid, decrease polynomially in sample size. A non-overlapping block bootstrap is also studied as a more flexible alternative. The above results are established under the general physical/functional dependence framework proposed in Wu (2005). Our work can be viewed as a substantive extension of Chernozhukov et al. (2013) to time series based on a variant of Stein's method developed therein.

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Efficient semiparametric estimation in generalized partially linear additive models for longitudinal/clustered data

We consider efficient estimation of the Euclidean parameters in a generalized partially linear additive models for longitudinal/clustered data when multiple covariates need to be modeled nonparametrically, and propose an estimation procedure based on a spline approximation of the nonparametric part of the model and the generalized estimating equations (GEE). Although the model in consideration is natural and useful in many practical applications, the literature on this model is very limited because of challenges in dealing with dependent data for nonparametric additive models. We show that the proposed estimators are consistent and asymptotically normal even if the covariance structure is misspecified. An explicit consistent estimate of the asymptotic variance is also provided. Moreover, we derive the semiparametric efficiency score and information bound under general moment conditions. By showing that our estimators achieve the semiparametric information bound, we effectively establish their efficiency in a stronger sense than what is typically considered for GEE. The derivation of our asymptotic results relies heavily on the empirical processes tools that we develop for the longitudinal/clustered data. Numerical results are used to illustrate the finite sample performance of the proposed estimators.

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Local and global asymptotic inference in smoothing spline models

This article studies local and global inference for smoothing spline estimation in a unified asymptotic framework. We first introduce a new technical tool called functional Bahadur representation, which significantly generalizes the traditional Bahadur representation in parametric models, that is, Bahadur [Ann. Inst. Statist. Math. 37 (1966) 577-580]. Equipped with this tool, we develop four interconnected procedures for inference: (i) pointwise confidence interval; (ii) local likelihood ratio testing; (iii) simultaneous confidence band; (iv) global likelihood ratio testing. In particular, our confidence intervals are proved to be asymptotically valid at any point in the support, and they are shorter on average than the Bayesian confidence intervals proposed by Wahba [J. R. Stat. Soc. Ser. B Stat. Methodol. 45 (1983) 133-150] and Nychka [J. Amer. Statist. Assoc. 83 (1988) 1134-1143]. We also discuss a version of the Wilks phenomenon arising from local/global likelihood ratio testing. It is also worth noting that our simultaneous confidence bands are the first ones applicable to general quasi-likelihood models. Furthermore, issues relating to optimality and efficiency are carefully addressed. As a by-product, we discover a surprising relationship between periodic and nonperiodic smoothing splines in terms of inference.

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Sparse and Efficient Estimation for Partial Spline Models with Increasing Dimension

We consider model selection and estimation for partial spline models and propose a new regularization method in the context of smoothing splines. The regularization method has a simple yet elegant form, consisting of roughness penalty on the nonparametric component and shrinkage penalty on the parametric components, which can achieve function smoothing and sparse estimation simultaneously. We establish the convergence rate and oracle properties of the estimator under weak regularity conditions. Remarkably, the estimated parametric components are sparse and efficient, and the nonparametric component can be estimated with the optimal rate. The procedure also has attractive computational properties. Using the representer theory of smoothing splines, we reformulate the objective function as a LASSO-type problem, enabling us to use the LARS algorithm to compute the solution path. We then extend the procedure to situations when the number of predictors increases with the sample size and investigate its asymptotic properties in that context. Finite-sample performance is illustrated by simulations.

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