Guangrong He | Searcharxiv

arXiv2026

Structured Scaling of AI Discovery Across Diverse Scientific Domains

Scientific discovery often requires many cycles of proposing, testing, and refining candidate solutions. Language models can increasingly participate in these loops, but simply generating more attempts does not ensure progress: parallel searches may duplicate one another and iterative refinement may become trapped in poor directions. The central challenge is therefore not only to scale AI-driven discovery, but to structure that scaling so that evaluation signals compound over time. Here we introduce SimpleTES (Simple Test-time Evaluation-driven Scaling), a framework that focuses on the structured scaling of AI discovery loops, organizing evaluator queries across independent trajectories, iterative refinement, local candidate selection, and the selective reuse of evaluated histories. Drawing on structural features of scientific communities, SimpleTES uses a single open-source GPT-OSS model to establish new state-of-the-art solutions across 28 open-ended problems in diverse scientific domains ranging from quantum physics and astronomy to biology, AI, and mathematics. These include a 24.5% reduction in quantum circuit compilation overhead, up to 23% lower propulsive cost for deep-space trajectories, a 2.17x faster lasso-path solver, an 8.5% lower-error whole-brain neural-activity predictor, the fastest reported TriMul kernel, and new mathematical constructions beyond prior human or AI records. We further post-train the model for long-horizon discovery by assigning each attempt the final outcome of the trajectory it helped produce. This improves performance on both training and held-out mathematics problems, further advancing the frontier. Together, these results establish structured scaling as a general mechanism for advancing AI scientific discovery.

cs.LG↗

arXiv2025

Toward Cost-Efficient Serving of Mixture-of-Experts with Asynchrony

Mixture-of-Experts (MoE) architectures offer the promise of larger model capacity without the prohibitive costs of fully dense designs. However, in real-world inference serving, load skew across experts often leads to suboptimal device utilization and excessive synchronization overheads. This paper introduces Asynchronous Expert Parallelism (AEP), a new paradigm that decouples layer execution from barrier-style synchronization. By dynamically queuing tokens at each layer (referred to as $μ$-queuing) and adaptively re-batching them on demand, GPUs avoid waiting for straggling experts and instead continuously process whichever layer is ready. This asynchronous approach mitigates two major inefficiencies in traditional expert-parallel systems: (1) idle GPU time while waiting for the hottest expert, and (2) small-batch executions on colder experts that waste memory bandwidth. We implement these ideas in a serving system called AMoE, which disaggregates attention from expert layers and uses a defragging scheduler to reduce batch fragmentation. Evaluations on prototype MoE models show that AMoE improves throughput by up to 2.7x compared to state-of-the-art baselines, incurring a manageable latency penalty and providing a cost-effective operating point. Furthermore, experiments demonstrate nearly linear scalability to multi-node settings, whereas the baseline system shows no throughput increase even when the number of GPUs is doubled.

cs.DC↗