arXiv subjects

Guanhong Miao

Publications and source records attributed to Guanhong Miao.

5 recordsLinked to original sources

arXiv2023

Reducing Noise Level in Differential Privacy through Matrix Masking

Differential privacy schemes have been widely adopted in recent years to address issues of data privacy protection. We propose a new Gaussian scheme combining with another data protection technique, called random orthogonal matrix masking, to achieve $(\varepsilon, δ)$-differential privacy (DP) more efficiently. We prove that the additional matrix masking significantly reduces the rate of noise variance required in the Gaussian scheme to achieve $(\varepsilon, δ)-$DP in big data setting. Specifically, when $\varepsilon \to 0$, $δ\to 0$, and the sample size $n$ exceeds the number $p$ of attributes by $(n-p)=O(ln(1/δ))$, the required additive noise variance to achieve $(\varepsilon, δ)$-DP is reduced from $O(ln(1/δ)/\varepsilon^2)$ to $O(1/\varepsilon)$. With much less noise added, the resulting differential privacy protected pseudo data sets allow much more accurate inferences, thus can significantly improve the scope of application for differential privacy.

cs.CR↗

arXiv2023

Real-time privacy preserving disease diagnosis using ECG signal

The rapid development in Internet of Medical Things (IoMT) boosts the opportunity for real-time health monitoring using various data types such as electroencephalography (EEG) and electrocardiography (ECG). Security issues have significantly impeded the e-healthcare system implementation. Three important challenges for privacy preserving system need to be addressed: accurate diagnosis, privacy protection without compromising accuracy, and computation efficiency. It is essential to guarantee prediction accuracy since disease diagnosis is strongly related to health and life. By implementing matrix encryption method, we propose a real-time disease diagnosis scheme using support vector machine (SVM). A biomedical signal provided by the client is diagnosed such that the server does not get any information about the signal as well as the final result of the diagnosis while the proposed scheme also achieves confidentiality of the SVM classifier and the server's medical data. The proposed scheme has no accuracy degradation. Experiments on real-world data illustrate the high efficiency of the proposed scheme. It takes less than 1 second to derive the disease diagnosis result using a device with 4Gb RAMs, suggesting the feasibility to implement real-time privacy preserving health monitoring.

cs.CR↗

arXiv2022

Efficient Privacy Preserving Logistic Regression for Horizontally Distributed Data

Internet of Things devices are expanding rapidly and generating huge amount of data. There is an increasing need to explore data collected from these devices. Collaborative learning provides a strategic solution for the Internet of Things settings but also raises public concern over data privacy. In recent years, large amount of privacy preserving techniques have been developed based on secure multi-party computation and differential privacy. A major challenge of collaborative learning is to balance disclosure risk and data utility while maintaining high computation efficiency. In this paper, we proposed privacy preserving logistic regression model using matrix encryption approach. The secure scheme is resilient to chosen plaintext attack, known plaintext attack, and collusion attack that could compromise any agencies in the collaborative learning. Encrypted model estimate is decrypted to provide true model results with no accuracy degradation. Verification phase is implemented to examine dishonest behavior among agencies. Experimental evaluations demonstrate fast convergence rate and high efficiency of proposed scheme.

cs.CR↗

arXiv2022

Linear Model Against Malicious Adversaries with Local Differential Privacy

Scientific collaborations benefit from collaborative learning of distributed sources, but remain difficult to achieve when data are sensitive. In recent years, privacy preserving techniques have been widely studied to analyze distributed data across different agencies while protecting sensitive information. Most existing privacy preserving techniques are designed to resist semi-honest adversaries and require intense computation to perform data analysis. Secure collaborative learning is significantly difficult with the presence of malicious adversaries who may deviates from the secure protocol. Another challenge is to maintain high computation efficiency with privacy protection. In this paper, matrix encryption is applied to encrypt data such that the secure schemes are against malicious adversaries, including chosen plaintext attack, known plaintext attack, and collusion attack. The encryption scheme also achieves local differential privacy. Moreover, cross validation is studied to prevent overfitting without additional communication cost. Empirical experiments on real-world datasets demonstrate that the proposed schemes are computationally efficient compared to existing techniques against malicious adversary and semi-honest model.

cs.CR↗

arXiv2022

A gated group sequential design for seamless Phase II/III trial with subpopulation selection

Due to the high cost and high failure rate of Phase III trials, seamless Phase II/III designs are more and more popular to trial efficiency. A potential attraction of Phase II/III design is to allow a randomized proof-of-concept stage prior to committing to the full cost of the Phase III trial. Population selection during the trial allows a trial to adapt and focus investment where it is most likely to provide patient benefit. Motivated by a clinical trial to find the population that potential benefits with dual-primary endpoints progression free survival (PFS) and overall survival (OS), we propose a gated group sequential design for a seamless Phase II/III trial design with population selection. The investigated design controls the familywise error rate and allows multiple interim analyses to enable early stopping for efficacy or futility. Simulations and an illustrative example suggest that the proposed gated group sequential design can have more power than the commonly used classical group sequential design, and reduces the patient's exposure to less effective treatment if the complementary sub-group has less significant treatment effect. The proposed design has the potential to save drug development cost and more quickly fulfill unmet medical needs.

stat.AP↗