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Guodong Pang

Publications and source records attributed to Guodong Pang.

At least 37 records · Page 2Linked to original sources

Functional law of large numbers and PDEs for epidemic models with infection-age dependent infectivity

We study epidemic models where the infectivity of each individual is a random function of the infection age (the elapsed time of infection). To describe the epidemic evolution dynamics, we use a stochastic process that tracks the number of individuals at each time that have been infected for less than or equal to a certain amount of time, together with the aggregate infectivity process. We establish the functional law of large numbers (FLLN) for the stochastic processes that describe the epidemic dynamics. The limits are described by a set of deterministic integral equations, which has a further characterization using PDEs under some regularity conditions. The solutions are characterized with boundary conditions that are given by a system of Volterra equations. We also characterize the equilibrium points for the PDEs in the SIS model with infection-age dependent infectivity. To establish the FLLNs, we employ a useful criterion for weak convergence for the two-parameter processes together with useful representations for the relevant processes via Poisson random measures.

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Recent Advances in Epidemic Modeling: Non-Markov Stochastic Models and their Scaling Limits

In this survey paper, we review the recent advances in individual based non--Markovian epidemic models. They include epidemic models with a constant infectivity rate, varying infectivity rate or infection-age dependent infectivity, infection-age recovery rate (or equivalently, general law of infectious period), as well as varying susceptibility/immunity. We focus on the scaling limits with a large population, functional law of large numbers (FLLN) and functional central limit theorems (FCLT), while the large and moderate deviations for some Markovian epidemic models are also reviewed. In the FLLN, the limits are a set of Volterra integral equations, and in the FCLT, the limits are stochastic Volterra integral equations driven by Gaussian processes. We relate our deterministic limits to the results in the seminal papers by Kermack and McKendrick published in 1927, 1932 and 1933, where the varying infectivity and susceptibility/immunity were already considered. We also discuss some extensions, including models with heterogeneous population, spatial models and control problems, as well as open problems.

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An approximation to the invariant measure of the limiting diffusion of G/Ph/n+GI queues in the Halfin-Whitt regime and related asymptotics

In this paper, we develop a stochastic algorithm based on the Euler--Maruyama scheme to approximate the invariant measure of the limiting multidimensional diffusion of $G/Ph/n+GI$ queues in the Halfin-Whitt regime. Specifically, we prove a non-asymptotic error bound between the invariant measures of the approximate model from the algorithm and the limiting diffusion. To establish the error bound, we employ the recently developed Stein's method for multi-dimensional diffusions, in which the regularity of Stein's equation developed by Gurvich (2014, 2022) plays a crucial role. We further prove the central limit theorem (CLT) and the moderate deviation principle (MDP) for the occupation measures of the limiting diffusion of $G/Ph/n+GI$ queues and its Euler-Maruyama scheme. In particular, the variances in the CLT and MDP associated with the limiting diffusion are determined by Stein's equation and Malliavin calculus, in which properties of a mollified diffusion and an associated weighted occupation time play a crucial role.

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Functional central limit theorems for epidemic models with varying infectivity

In this paper, we prove functional central limit theorems (FCLTs) for a stochastic epidemic model with varying infectivity and general infectious periods recently introduced in Forien, Pang and Pardoux (2020).The infectivity process (total force of infection at each time) is composed of the independent infectivity random functions of each infectious individual, which starts at the time of infection. These infectivity random functions induce the infectious periods (as well as exposed, recovered or immune periods in full generality), whose probability distributions can be very general. The epidemic model includes the generalized non-Markovian SIR, SEIR, SIS, SIRS models with infection-age dependent infectivity. In the FCLTs for the generalized SIR and SEIR models, the limits of the diffusion-scaled fluctuations of the infectivity and susceptible processes are a unique solution to a two-dimensional Gaussian-driven stochastic Volterra integral equations, and then given these solutions, the limits for the infected (exposed/infectious) and recovered processes are Gaussian processes expressed in terms of the solutions to those stochastic Volterra integral equations. We also present the FCLTs for the generalized SIS and SIRS models.

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Multi-patch epidemic models with general exposed and infectious periods

We study multi-patch epidemic models where individuals may migrate from one patch to another in either of the susceptible, exposed/latent, infectious and recovered states. We assume that infections occur both locally with a rate that depends on the patch as well as "from distance" from all the other patches. The exposed and infectious periods have general distributions, and are not affected by the possible migrations of the individuals. The migration processes in either of the three states are assumed to be Markovian, and independent of the exposed and infectious periods. We establish a functional law of large number (FLLN) and a function central limit theorem (FCLT) for the susceptible, exposed/latent, infectious and recovered processes. In the FLLN, the limit is determined by a set of Volterra integral equations. In the special case of deterministic exposed and infectious periods, the limit becomes a system of ODEs with delays. In the FCLT, the limit is given by a set of stochastic Volterra integral equations driven by a sum of independent Brownian motions and continuous Gaussian processes with an explicit covariance structure.

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Birth and Death Processes in Interactive Random Environments

This paper studies birth and death processes in interactive random environments where the birth and death rates and the dynamics of the state of the environment are dependent on each other. Two models of a random environment are considered: a continuous-time Markov chain (finite or countably infinite) and a reflected (jump) diffusion process. The background is determined by a joint Markov process carrying a specific interactive mechanism, with an explicit invariant measure whose structure is similar to a product form. We discuss a number of queueing and population-growth models and establish conditions under which the above-mentioned invariant measure can be derived. Next, an analysis of the rate of convergence to stationarity is performed for the models under consideration. We consider two settings leading to either an exponential or a polynomial convergence rate. In both cases we assume that the underlying environmental Markov process has an exponential rate of convergence, but the convergence rate of the joint Markov process is determined by certain conditions on the birth and death rates. To prove these results a coupling method turns out to be useful.

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Multi-patch multi-group epidemic model with varying infectivity

This paper presents a law of large numbers result, as the size of the population tends to infinity, of SIR stochastic epidemic models, for a population distributed over $L$ distinct patches (with migrations between them) and $K$ distinct groups (possibly age groups). The limit is a set of Volterra-type integral equations, and the result shows the effects of both spatial and population heterogeneity. The novelty of the model is that the infectivity of an infected individual is infection age dependent. More precisely, to each infected individual is attached a random infection-age dependent infectivity function, such that the various random functions attached to distinct individuals are i.i.d. The proof involves a novel construction of a sequence of i.i.d. processes to invoke the law of large numbers for processes in $D$, by using the solution of a MacKean-Vlasov type Poisson-driven stochastic equation (as in the propagation of chaos theory). We also establish an identity using the Feynman-Kac formula for an adjoint backward ODE. The advantage of this approach is that it assumes much weaker conditions on the random infectivity functions than our earlier work for the homogeneous model in [20], where standard tightness criteria for convergence of stochastic processes were employed. To illustrate this new approach, we first explain the new proof under the weak assumptions for the homogeneous model, and then describe the multipatch-multigroup model and prove the law of large numbers for that model.

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Uniform stability of some large-scale parallel server networks

In this paper we study the uniform stability properties of two classes of parallel server networks with multiple classes of jobs and multiple server pools of a tree topology. These include a class of networks with a single non-leaf server pool, such as the 'N' and 'M' models, and networks of any tree topology with class-dependent service rates. We show that with $\sqrt{n}$ safety staffing, and no abandonment, in the Halfin--Whitt regime, the diffusion-scaled controlled queueing processes are exponentially ergodic and their invariant probability distributions are tight, uniformly over all stationary Markov controls. We use a unified approach in which the same Lyapunov function is used in the study of the prelimit and diffusion limit. A parameter called the spare capacity (safety staffing) of the network plays a central role in characterizing the stability results: the parameter being positive is necessary and sufficient that the limiting diffusion is uniformly exponentially ergodic over all stationary Markov controls. We introduce the concept of "system-wide work conserving policies", which are defined as policies that minimize the number of idle servers at all times. This is stronger than the so-called joint work conservation. We show that, provided the spare capacity parameter is positive, the diffusion-scaled processes are geometrically ergodic and the invariant distributions are tight, uniformly over all "system-wide work conserving policies". In addition, when the spare capacity is negative we show that the diffusion-scaled processes are transient under any stationary Markov control, and when it is zero, they cannot be positive recurrent.

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Subexponential upper and lower bounds in Wasserstein distance for Markov processes

In this article, relying on Foster-Lyapunov drift conditions, we establish subexponential upper and lower bounds on the rate of convergence in the $\mathrm{L}^p$-Wasserstein distance for a class of irreducible and aperiodic Markov processes. We further discuss these results in the context of Markov Lévy-type processes. In the lack of irreducibility and/or aperiodicity properties, we obtain exponential ergodicity in the $\mathrm{L}^p$-Wasserstein distance for a class of Itô processes under an asymptotic flatness (uniform dissipativity) assumption. Lastly, applications of these results to specific processes are presented, including Langevin tempered diffusion processes, piecewise Ornstein-Uhlenbeck processes with jumps under constant and stationary Markov controls, and backward recurrence time chains, for which we provide a sharp characterization of the rate of convergence via matching upper and lower bounds.

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An approximation to steady-state of M/Ph/n+M queue

In this paper, we develop a stochastic algorithm based on Euler-Maruyama scheme to approximate the invariant measure of the limiting multidimensional diffusion of the $M/Ph/n+M$ queue. Specifically, we prove a non-asymptotic error bound between the invariant measures of the approximate model from the algorithm and the limiting diffusion of the queueing model. Our result also provides an approximation to the steady-state of the diffusion-scaled queueing processes in the Halfin-Whitt regime given the well established interchange of limits property. To establish the error bound, we employ the recently developed Stein's method for multi-dimensional diffusions, in which the regularity of Stein's equation developed by Gurvich \cite{Gur1} plays a crucial role. We further prove the central limit theorem (CLT) and the moderate deviation principle (MDP) for the occupation measures of the limiting diffusion of the $M/Ph/n+M$ queue and its Euler-Maruyama scheme. In particular, the variance of the CLT of the limiting queue is determined by using Stein's equation and Malliavin calculus.

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Functional Limit Theorems for Non-Markovian Epidemic Models

We study non-Markovian stochastic epidemic models (SIS, SIR, SIRS, and SEIR), in which the infectious (and latent/exposing, immune) periods have a general distribution. We provide a representation of the evolution dynamics using the time epochs of infection (and latency/exposure, immunity). Taking the limit as the size of the population tends to infinity, we prove both a functional law of large number (FLLN) and a functional central limit theorem (FCLT) for the processes of interest in these models. In the FLLN, the limits are a unique solution to a system of deterministic Volterra integral equations, while in the FCLT, the limit processes are multidimensional Gaussian solutions of linear Volterra stochastic integral equations. In the proof of the FCLT, we provide an important Poisson random measures representation of the diffusion-scaled processes converging to Gaussian components driving the limit process.

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On system-wide safety staffing of large-scale parallel server networks

We introduce a "system-wide safety staffing" (SWSS) parameter for multiclass multi-pool networks of any tree topology, Markovian or non-Markovian, in the Halfin-Whitt regime. This parameter can be regarded as the optimal reallocation of the capacity fluctuations (positive or negative) of order $\sqrt{n}$ when each server pool employs a square-root staffing rule. We provide an explicit form of the SWSS as a function of the system parameters, which is derived using a graph theoretic approach based on Gaussian elimination. For Markovian networks, we give an equivalent characterization of the SWSS parameter via the drift parameters of the limiting diffusion. We show that if the SWSS parameter is negative, the limiting diffusion and the diffusion-scaled queueing processes are transient under any Markov control, and cannot have a stationary distribution when this parameter is zero. If it is positive, we show that the diffusion-scaled queueing processes are uniformly stabilizable, that is, there exists a scheduling policy under which the stationary distributions of the controlled processes are tight over the size of the network. In addition, there exists a control under which the limiting controlled diffusion is exponentially ergodic. Thus we have identified a necessary and sufficient condition for the uniform stabilizability of such networks in the Halfin-Whitt regime. We use a constant control resulting from the leaf elimination algorithm to stabilize the limiting controlled diffusion, while a family of Markov scheduling policies which are easy to compute are used to stabilize the diffusion-scaled processes. Finally, we show that under these controls the processes are exponentially ergodic and the stationary distributions have exponential tails.

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Epidemic models with varying infectivity

We introduce an epidemic model with varying infectivity and general exposed and infectious periods, where the infectivity of each individual is a random function of the elapsed time since infection, those function being i.i.d. for the various individuals in the population. This approach models infection-age dependent infectivity, and extends the classical SIR and SEIR models. We focus on the infectivity process (total force of infection at each time), and prove a functional law of large number (FLLN). In the deterministic limit of this LLN, the infectivity process and the susceptible process are determined by a two-dimensional deterministic integral equation. From its solutions, we then derive the exposed, infectious and recovered processes, again using integral equations. For the early phase, we study the stochastic model directly by using an approximate (non--Markovian) branching process, and show that the epidemic grows at an exponential rate on the event of non-extinction, which matches the rate of growth derived from the deterministic linearized equations. We also use these equations to derive the basic reproduction number $R_0$ during the early stage of an epidemic, in terms of the average individual infectivity function and the exponential rate of growth of the epidemic.

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Path Properties of a Generalized Fractional Brownian Motion

The generalized fractional Brownian motion is a Gaussian self-similar process whose increments are not necessarily stationary. It appears in applications as the scaling limit of a shot noise process with a power law shape function and non-stationary noises with a power-law variance function. In this paper we study sample path properties of the generalized fractional Brownian motion, including Holder continuity, path differentiability/non-differentiability, and functional and local Law of the Iterated Logarithms.

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Stationary Distributions and Convergence for M/M/1 Queues in Interactive Random Environment

A Markovian single-server queue is studied in an interactive random environment. The arrival and service rates of the queue depend on the environment, while the transition dynamics of the random environment depends on the queue length. We consider in detail two types of Markov random environments: a pure jump process and a reflected jump-diffusion. In both cases, the joint dynamics is constructed so that the stationary distribution can be explicitly found in a simple form (weighted geometric). We also derive an explicit estimate for exponential rate of convergence to the stationary distribution via coupling.

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On uniform exponential ergodicity of Markovian multiclass many-server queues in the Halfin-Whitt regime

We study ergodic properties of Markovian multiclass many-server queues which are uniform over scheduling policies, as well as the size n of the system. The system is heavily loaded in the Halfin-Whitt regime, and the scheduling policies are work-conserving and preemptive. We provide a unified approach via a Lyapunov function method that establishes Foster-Lyapunov equations for both the limiting diffusion and the prelimit diffusion-scaled queueing processes simultaneously. We first study the limiting controlled diffusion, and we show that if the spare capacity (safety staffing) parameter is positive, then the diffusion is exponentially ergodic uniformly over all stationary Markov controls, and the invariant probability measures have uniform exponential tails. This result is sharp, since when there is no abandonment and the spare capacity parameter is negative, then the controlled diffusion is transient under any Markov control. In addition, we show that if all the abandonment rates are positive, the invariant probability measures have sub-Gaussian tails, regardless whether the spare capacity parameter is positive or negative. Using the above results, we proceed to establish the corresponding ergodic properties for the diffusion-scaled queueing processes. In addition to providing a simpler proof of the results in Gamarnik and Stolyar [Queueing Syst (2012) 71:25-51], we extend these results to the multiclass models with renewal arrival processes, albeit under the assumption that the mean residual life functions are bounded. For the Markovian model with Poisson arrivals, we obtain stronger results and show that the convergence to the stationary distribution is at an exponential rate uniformly over all work-conserving stationary Markov scheduling policies.

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Exponential ergodicity and steady-state approximations for a class of Markov processes under fast regime switching

We study ergodic properties of a class of Markov-modulated general birth-death processes under fast regime switching. The first set of results concerns the ergodic properties of the properly scaled joint Markov process with a parameter that is taken large. Under very weak hypotheses, we show that if the averaged process is exponentially ergodic for large values of the parameter, then the same applies to the original joint Markov process. The second set of results concerns steady-state diffusion approximations, under the assumption that the 'averaged' fluid limit exists. Here, we establish convergence rates for the moments of the approximating diffusion process to those of the Markov modulated birth-death process. This is accomplished by comparing the generator of the approximating diffusion and that of the joint Markov process. We also provide several examples which demonstrate how the theory can be applied.

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Optimal scheduling of critically loaded multiclass GI/M/n+M queues in an alternating renewal environment

In this paper, we study optimal control problems for multiclass GI/M/n+M queues in an alternating renewal (up-down) random environment in the Halfin-Whitt regime. Assuming that the downtimes are asymptotically negligible and only the service processes are affected, we show that the limits of the diffusion-scaled state processes under non-anticipative, preemptive, work-conserving scheduling policies, are controlled jump diffusions driven by a compound Poisson jump process. We establish the asymptotic optimality of the infinite-horizon discounted and long-run average (ergodic) problems for the queueing dynamics. Since the process counting the number of customers in each class is not Markov, the usual martingale arguments for convergence of mean empirical measures cannot be applied. We surmount this obstacle by demonstrating the convergence of the generators of an augmented Markovian model which incorporates the age processes of the renewal interarrival times and downtimes. We also establish long-run average moment bounds of the diffusion-scaled queueing processes under some (modified) priority scheduling policies. This is accomplished via Foster-Lyapunov equations for the augmented Markovian model.

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