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Guoquan Wei

Publications and source records attributed to Guoquan Wei.

4 recordsLinked to original sources

FrequencyCT: Frequency Domain Self-supervised Low-dose CT Denoising

Despite extensive research on computed tomography (CT) denoising, few studies exploit projection-domain data characteristics to mitigate noise correlation. To bridge this gap, this work proposes FrequencyCT, the first zero-shot self-supervised method for pseudo-sample generation in the frequency domain for low-dose CT denoising. Specifically, by exploiting the distinct frequency-domain distributions of noise and true signal, a regional low-frequency anchoring technique is proposed. Applying phase-preserving noise and mask perturbations to the high-frequency region generates pseudo-samples for self-supervision. Driven by the exponential correlation between noise variance of noisy projections and the underlying true signal, consistent data truncation is applied to the generated samples to stabilize optimization gradients. Evaluation results on multiple public and real datasets confirm the clinical application potential of this research, which provides an innovative perspective for the field of denoising. The code is available at: https://github.com/yqx7150/FrequencyCT.

cs.CV

SCOUT: Fast Spectral CT Imaging in Ultra LOw-data Regimes via PseUdo-label GeneraTion

Noise and artifacts during computed tomography (CT) scans are a fundamental challenge affecting disease diagnosis. However, current methods either involve excessively long reconstruction times or rely on data-driven models for optimization, failing to adequately consider the valuable information inherent in the data itself, especially medical 3D data. This work proposes a reconstruction method under ultra-low raw data conditions, requiring no external data and avoiding lengthy pre-training processes. By leveraging spatial nonlocal similarity and the conjugate properties of the projection domain to generate pseudo-3D data for self-supervised training, high-fidelity results can be achieved in a very short time. Extensive experiments demonstrate that this method not only mitigates detector-induced ring artifacts but also exhibits unprecedented capabilities in detail recovery. This method provides a new paradigm for research using unlabeled raw projection data. Code is available at https://github.com/yqx7150/SCOUT.

cs.CV

Extendable Generalization Self-Supervised Diffusion for Low-Dose CT Reconstruction

Current methods based on deep learning for self-supervised low-dose CT (LDCT) reconstruction, while reducing the dependence on paired data, face the problem of significantly decreased generalization when training with single-dose data and extending to other doses. To enable dose-extensive generalization using only single-dose projection data for training, this work proposes a novel method of Extendable GENeraLization self-supervised Diffusion (EGenDiff) for low-dose CT reconstruction. Specifically, a contextual subdata self-enhancing similarity strategy is designed to provide an initial prior for the subsequent progress. During training, the initial prior is used to combine knowledge distillation with a deep combination of latent diffusion models for optimizing image details. On the stage of inference, the pixel-wise self-correcting fusion technique is proposed for data fidelity enhancement, resulting in extensive generalization of higher and lower doses or even unseen doses. EGenDiff requires only LDCT projection data for training and testing. Comprehensive evaluation on benchmark datasets, clinical data, photon counting CT data, and across all three anatomical planes (transverse, coronal, and sagittal) demonstrates that EGenDiff enables extendable generalization multi-dose, yielding reconstructions that consistently outperform leading existing methods.

cs.CV

FD-DiT: Frequency Domain-Directed Diffusion Transformer for Low-Dose CT Reconstruction

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models has been a promising approach for image generation. Nevertheless, existing methods exhibit limitations in preserving finegrained image details. To address this issue, frequency domain-directed diffusion transformer (FD-DiT) is proposed for LDCT reconstruction. FD-DiT centers on a diffusion strategy that progressively introduces noise until the distribution statistically aligns with that of LDCT data, followed by denoising processing. Furthermore, we employ a frequency decoupling technique to concentrate noise primarily in high-frequency domain, thereby facilitating effective capture of essential anatomical structures and fine details. A hybrid denoising network is then utilized to optimize the overall data reconstruction process. To enhance the capability in recognizing high-frequency noise, we incorporate sliding sparse local attention to leverage the sparsity and locality of shallow-layer information, propagating them via skip connections for improving feature representation. Finally, we propose a learnable dynamic fusion strategy for optimal component integration. Experimental results demonstrate that at identical dose levels, LDCT images reconstructed by FD-DiT exhibit superior noise and artifact suppression compared to state-of-the-art methods.

eess.IV