arXiv subjects

Gustavo Guerberoff

Publications and source records attributed to Gustavo Guerberoff.

7 recordsLinked to original sources

arXiv2026

Absorption and fixation times for evolutionary processes on graphs

In this paper, we study the absorption and fixation times for evolutionary processes on graphs, under different updating rules. While in Moran process a single neighbour is randomly chosen to be replaced, in proliferation processes other neighbours can be replaced using Bernoulli or binomial draws depending on $0 < p \leq 1$. There is a critical value $p_c$ such that the proliferation is advantageous or disadvantageous in terms of fixation probability depending on whether $p > p_c$ or $p < p_c$. We clarify the role of symmetries for computing the fixation time in Moran process. We show that the Maruyama-Kimura symmetry depend on the graph structure induced in each state, implying asymmetry for all graphs except cliques and cycles. There is a fitness value, not necessarily $1$, beyond which the fixation time decreases monotonically. We apply Harris' graphical method to prove that the fixation time decreases monotonically depending on $p$. Thus there exists another value $p_t$ for which the proliferation is advantageous or disadvantageous in terms of time. However, at the critical level $p=p_c$, the proliferation is highly advantageous when $r \to +\infty$.

q-bio.PE↗

arXiv2020

Analysis and Reliability of Separable Systems

The operation of a system, such as a vehicle, communication network or automatic process, heavily depends on the correct operation of its components. A Stochastic Binary System (SBS) mathematically models the behavior of on-off systems, where the components are subject to probabilistic failures. Our goal is to understand the reliability of the global system. The reliability evaluation of an SBS belongs to the class of NP-Hard problems, and the combinatorics of SBS imposes several challenges. In a previous work by the same authors, a special sub-class of SBSs called "separable systems" was introduced. These systems accept an efficient representation by a linear inequality on the binary states of the components. However, the reliability evaluation of separable systems is still hard. A theoretical contribution in the understanding of separable systems is given. We fully characterize separable systems under the all-terminal reliability model, finding that they admit efficient reliability evaluation in this relevant context.

cs.DM↗

arXiv2018

Nonparametric optimization of short-term confidence bands for wind power generation

The increasing rate of penetration of non-conventional renewable energies is affecting the traditional assumption of controllability over energy sources. Power dispatching scheduling methods need to integrate the intrinsic randomness of some new sources, among which, wind energy is particularly difficult to treat. This work aims on the construction of confidence bands around wind energy forecasts. Complementarily, the proposed technique can be extended to integrate multiple forecasts into a single one, whose band's width is narrower at the same level of confidence. The work is based upon a real-world application case, developed for the Uruguayan Electricity Market, a world leader country in the penetration of renewable energies.

eess.SP↗

arXiv2015

Hidden Markov Models for Gene Sequence Classification: Classifying the VSG genes in the Trypanosoma brucei Genome

The article presents an application of Hidden Markov Models (HMMs) for pattern recognition on genome sequences. We apply HMM for identifying genes encoding the Variant Surface Glycoprotein (VSG) in the genomes of Trypanosoma brucei (T. brucei) and other African trypanosomes. These are parasitic protozoa causative agents of sleeping sickness and several diseases in domestic and wild animals. These parasites have a peculiar strategy to evade the host's immune system that consists in periodically changing their predominant cellular surface protein (VSG). The motivation for using patterns recognition methods to identify these genes, instead of traditional homology based ones, is that the levels of sequence identity (amino acid and DNA sequence) amongst these genes is often below of what is considered reliable in these methods. Among pattern recognition approaches, HMM are particularly suitable to tackle this problem because they can handle more naturally the determination of gene edges. We evaluate the performance of the model using different number of states in the Markov model, as well as several performance metrics. The model is applied using public genomic data. Our empirical results show that the VSG genes on T. brucei can be safely identified (high sensitivity and low rate of false positives) using HMM.

q-bio.GN↗

arXiv2013

A stochastic microscopic model for the dynamics of antigenic variation

We present a novel model that describes the within-host evolutionary dynamics of parasites undergoing antigenic variation. The approach uses a multi-type branching process with two types of entities defined according to their relationship with the immune system: clans of resistant parasitic cells (i.e. groups of cells sharing the same antigen not yet recognized by the immune system) that may become sensitive, and individual sensitive cells that can acquire a new resistance thus giving rise to the emergence of a new clan. The simplicity of the model allows analytical treatment to determine the subcritical and supercritical regimes in the space of parameters. By incorporating a density-dependent mechanism the model is able to capture additional relevant features observed in experimental data, such as the characteristic parasitemia waves. In summary our approach provides a new general framework to address the dynamics of antigenic variation which can be easily adapted to cope with broader and more complex situations.

q-bio.PE↗

arXiv2010

Statistical constraints on binary black hole inspiral dynamics

We perform a statistical analysis of the binary black hole problem in the post-Newtonian approximation by systematically sampling and evolving the parameter space of initial configurations for quasi-circular inspirals. Through a principal component analysis of spin and orbital angular momentum variables we systematically look for uncorrelated quantities and find three of them which are highly conserved in a statistical sense, both as functions of time and with respect to variations in initial spin orientations. We also look for and find the variables that account for the largest variations in the problem. We present binary black hole simulations of the full Einstein equations analyzing to what extent these results might carry over to the full theory in the inspiral and merger regimes. Among other applications these results should be useful both in semi-analytical and numerical building of templates of gravitational waves for gravitational wave detectors.

gr-qc↗

arXiv2009

Integrating Post-Newtonian Equations on Graphics Processing Units

We report on early results of a numerical and statistical study of binary black hole inspirals. The two black holes are evolved using post-Newtonian approximations starting with initially randomly distributed spin vectors. We characterize certain aspects of the distribution shortly before merger. In particular we note the uniform distribution of black hole spin vector dot products shortly before merger and a high correlation between the initial and final black hole spin vector dot products in the equal-mass, maximally spinning case. These simulations were performed on Graphics Processing Units, and we demonstrate a speed-up of a factor 50 over a more conventional CPU implementation.

gr-qc↗