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Haibo Wu

Publications and source records attributed to Haibo Wu.

8 recordsLinked to original sources

Partial Wavelet Canonical Coherence for Nonstationary Signals with High Dimensional Confounders

We develop Partial Wavelet Canonical Coherence for measuring the direct canonical association between two multivariate nonstationary time series after adjustment for possibly high-dimensional confounders. To the best of our knowledge, this is the first method that establishes a frequency-domain formulation of the partial canonical correlation analysis for time series. Through a wavelet approach, the proposed method yields a scale-specific, time-varying measure of association capable to work with potential data nonstationarities. We formulate the target quantity under the multivariate locally stationary wavelet framework, develop principled estimation through local wavelet spectral matrices, and incorporate principal-component reduction for stable adjustment in high-dimensions. Simulations show that the method removes spurious marginal association induced by confounding and accurately recovers direct association, including in higher-dimensional settings. Analysis of U.S. exchange-traded funds reveals substantial time-varying and scale-dependent direct canonical association after adjustment for external market effects.

stat.ME

Wavelet Canonical Coherence for Nonstationary Signals

Understanding the evolving dependence between two clusters of multivariate signals is fundamental in neuroscience and other domains where sub-networks in a system interact dynamically over time. Despite the growing interest in multivariate time series analysis, existing methods for between-clusters dependence typically rely on the assumption of stationarity and lack the temporal resolution to capture transient, frequency-specific interactions. To overcome this limitation, we propose scale-specific wavelet canonical coherence (WaveCanCoh), a novel framework that extends canonical coherence analysis to the nonstationary setting by leveraging the multivariate locally stationary wavelet model. The proposed WaveCanCoh enables the estimation of time-varying canonical coherence between clusters, providing interpretable insight into scale-specific time-varying interactions between clusters. Through extensive simulation studies, we demonstrate that WaveCanCoh accurately recovers true coherence structures under both locally stationary and general nonstationary conditions. Application to local field potential (LFP) activity data recorded from the hippocampus reveals distinct dynamic coherence patterns between correct and incorrect memory-guided decisions, illustrating the capacity of the method to detect behaviorally relevant neural coordination. These results highlight WaveCanCoh as a flexible and principled tool for modeling complex cross-group dependencies in nonstationary multivariate systems. The code for WaveCanCoh is available at: https://github.com/mhaibo/WaveCanCoh.git.

stat.ME

Promptable Representation Distribution Learning and Data Augmentation for Gigapixel Histopathology WSI Analysis

Gigapixel image analysis, particularly for whole slide images (WSIs), often relies on multiple instance learning (MIL). Under the paradigm of MIL, patch image representations are extracted and then fixed during the training of the MIL classifiers for efficiency consideration. However, the invariance of representations makes it difficult to perform data augmentation for WSI-level model training, which significantly limits the performance of the downstream WSI analysis. The current data augmentation methods for gigapixel images either introduce additional computational costs or result in a loss of semantic information, which is hard to meet the requirements for efficiency and stability needed for WSI model training. In this paper, we propose a Promptable Representation Distribution Learning framework (PRDL) for both patch-level representation learning and WSI-level data augmentation. Meanwhile, we explore the use of prompts to guide data augmentation in feature space, which achieves promptable data augmentation for training robust WSI-level models. The experimental results have demonstrated that the proposed method stably outperforms state-of-the-art methods.

cs.CV

Slide-based Graph Collaborative Training for Histopathology Whole Slide Image Analysis

The development of computational pathology lies in the consensus that pathological characteristics of tumors are significant guidance for cancer diagnostics. Most existing research focuses on the inner-contextual information within each WSI yet ignores the possible inter-correlations between slides. As the development of tumors is a continuous process involving a series of histological, morphological, and genetic changes that accumulate over time, the similarities and differences between WSIs across various stages, grades, locations and patients should potentially contribute to the representation of WSIs and deserve to be taken into account in WSI modeling. To verify the advancement of introducing the slide inter-correlations into the representation learning of WSIs, we proposed a generic WSI analysis pipeline SlideGCD that can be adapted to any existing Multiple Instance Learning (MIL) frameworks and improve their performance. With the new paradigm, the prior knowledge of cancer development can participate in the end-to-end workflow, which concurrently initializes and refines the slide representation, as a guide for message passing in the slide-based graph. Extensive comparisons and experiments are conducted to validate the effectiveness and robustness of the proposed pipeline across 4 different tasks, including cancer subtyping, cancer staging, survival prediction, and gene mutation prediction, with 7 representative SOTA WSI analysis frameworks as backbones.

cs.CV

Pan-cancer Histopathology WSI Pre-training with Position-aware Masked Autoencoder

Large-scale pre-training models have promoted the development of histopathology image analysis. However, existing self-supervised methods for histopathology images primarily focus on learning patch features, while there is a notable gap in the availability of pre-training models specifically designed for WSI-level feature learning. In this paper, we propose a novel self-supervised learning framework for pan-cancer WSI-level representation pre-training with the designed position-aware masked autoencoder (PAMA). Meanwhile, we propose the position-aware cross-attention (PACA) module with a kernel reorientation (KRO) strategy and an anchor dropout (AD) mechanism. The KRO strategy can capture the complete semantic structure and eliminate ambiguity in WSIs, and the AD contributes to enhancing the robustness and generalization of the model. We evaluated our method on 7 large-scale datasets from multiple organs for pan-cancer classification tasks. The results have demonstrated the effectiveness and generalization of PAMA in discriminative WSI representation learning and pan-cancer WSI pre-training. The proposed method was also compared with 8 WSI analysis methods. The experimental results have indicated that our proposed PAMA is superior to the state-of-the-art methods. The code and checkpoints are available at https://github.com/WkEEn/PAMA.

cs.CV

Dynamic cross-scale wavelet coherence

This paper develops a novel statistical approach that allows for the {\em first time} the {\em cross}-oscillatory characterisation of temporally localised interactions between channels in a functional brain network. Brain signals are often nonstationary and the proposed framework uses wavelets as an effective tool for capturing (i) single-scale channel transient features, due to their adaptiveness to the dynamic signal properties, and (ii) cross-scale channel interactions, due to their multiscale nature. Our approach introduces scale-specific {\em subprocesses} and {\em cross-scale (CS) dependencies} for a new class of multivariate locally stationary (MvLSW) wavelet processes that we refer to as CS-MvLSW. Under this new model, we develop two consistent estimation procedures for the {\em localised} single- and cross-scale channel dependence. Extensive simulation studies demonstrate that the theoretically established properties hold in practice. The proposed CS-MvLSW framework remains accurate under pronounced cross-scale dependence, whereas existing MvLSW coherence estimates dramatically deteriorate even for single-scales when such complex structure is present. The proposed approach was used for electroencephalogram (EEG) data to study alterations in the functional connectivity structure in children diagnosed with attention deficit hyperactivity disorder (ADHD), and identified novel clinically pertinent cross-scale interactions in the functional brain network across the left and right hemispheres, differentiating brain connectivity between control and ADHD groups.

stat.ME

Multi-Microgrid Collaborative Optimization Scheduling Using an Improved Multi-Agent Soft Actor-Critic Algorithm

The implementation of a multi-microgrid (MMG) system with multiple renewable energy sources enables the facilitation of electricity trading. To tackle the energy management problem of a MMG system, which consists of multiple renewable energy microgrids belonging to different operating entities, this paper proposes a MMG collaborative optimization scheduling model based on a multi-agent centralized training distributed execution framework. To enhance the generalization ability of dealing with various uncertainties, we also propose an improved multi-agent soft actor-critic (MASAC) algorithm, which facilitates en-ergy transactions between multi-agents in MMG, and employs automated machine learning (AutoML) to optimize the MASAC hyperparameters to further improve the generalization of deep reinforcement learning (DRL). The test results demonstrate that the proposed method successfully achieves power complementarity between different entities, and reduces the MMG system operating cost. Additionally, the proposal significantly outperforms other state-of-the-art reinforcement learning algorithms with better economy and higher calculation efficiency.

eess.SY

All partitions have small parts - Gallai-Ramsey numbers of bipartite graphs

Gallai-colorings are edge-colored complete graphs in which there are no rainbow triangles. Within such colored complete graphs, we consider Ramsey-type questions, looking for specified monochromatic graphs. In this work, we consider monochromatic bipartite graphs since the numbers are known to grow more slowly than for non-bipartite graphs. The main result shows that it suffices to consider only $3$-colorings which have a special partition of the vertices. Using this tool, we find several sharp numbers and conjecture the sharp value for all bipartite graphs. In particular, we determine the Gallai-Ramsey numbers for all bipartite graphs with two vertices in one part and initiate the study of linear forests.

math.CO