arXiv subjects

Haitao Sun

Publications and source records attributed to Haitao Sun.

6 recordsLinked to original sources

arXiv2026

Multi-Catheter Digitization in Brachytherapy via Few-Shot Synthetic-to-Real Learning and Structure-Aware Tracking

Accurate catheter digitization in CT-guided interstitial brachytherapy is a critical but time-consuming task, especially for complex implant configurations. We developed a data-efficient, physics-guided framework for automated multi-catheter digitization with minimal clinical annotation. The pipeline consists of two stages. First, an implant region-aware network was pretrained on synthetic CT volumes with simulated metallic signatures and then fine-tuned using only 10 clinical cases. Second, a structure-aware reconstruction module combined a direction-constrained 3D Hough transform with synchronous physics-constrained inward tracking to separate adherent catheter trajectories. The method was evaluated by patient-level five-fold cross-validation on 203 treatment fractions from 38 patients. The fine-tuned network achieved an HD95 of 0.853 +/- 0.362 mm. End-to-end evaluation yielded an F1 score of 0.891 +/- 0.178, with shaft and tip errors of 0.334 +/- 0.367 mm and 0.896 +/- 0.680 mm, respectively. In cases with severe catheter adhesion, the tracking F1 score remained 0.843 +/- 0.190. The complete workflow required approximately 11.6 s per case. These results indicate that combining few-shot synthetic-to-real learning with physics-guided structural tracking can provide robust and efficient multi-catheter digitization for time-sensitive clinical workflows.

physics.med-ph↗

arXiv2025

Multi-needle Localization for Pelvic Seed Implant Brachytherapy based on Tip-handle Detection and Matching

Accurate multi-needle localization in intraoperative CT images is crucial for optimizing seed placement in pelvic seed implant brachytherapy. However, this task is challenging due to poor image contrast and needle adhesion. This paper presents a novel approach that reframes needle localization as a tip-handle detection and matching problem to overcome these difficulties. An anchor-free network, based on HRNet, is proposed to extract multi-scale features and accurately detect needle tips and handles by predicting their centers and orientations using decoupled branches for heatmap regression and polar angle prediction. To associate detected tips and handles into individual needles, a greedy matching and merging (GMM) method designed to solve the unbalanced assignment problem with constraints (UAP-C) is presented. The GMM method iteratively selects the most probable tip-handle pairs and merges them based on a distance metric to reconstruct 3D needle paths. Evaluated on a dataset of 100 patients, the proposed method demonstrates superior performance, achieving higher precision and F1 score compared to a segmentation-based method utilizing the nnUNet model,thereby offering a more robust and accurate solution for needle localization in complex clinical scenarios.

cs.CV↗

arXiv2025

An Iterative LLM Framework for SIBT utilizing RAG-based Adaptive Weight Optimization

Seed implant brachytherapy (SIBT) is an effective cancer treatment modality; however, clinical planning often relies on manual adjustment of objective function weights, leading to inefficiencies and suboptimal results. This study proposes an adaptive weight optimization framework for SIBT planning, driven by large language models (LLMs). A locally deployed DeepSeek-R1 LLM is integrated with an automatic planning algorithm in an iterative loop. Starting with fixed weights, the LLM evaluates plan quality and recommends new weights in the next iteration. This process continues until convergence criteria are met, after which the LLM conducts a comprehensive evaluation to identify the optimal plan. A clinical knowledge base, constructed and queried via retrieval-augmented generation (RAG), enhances the model's domain-specific reasoning. The proposed method was validated on 23 patient cases, showing that the LLM-assisted approach produces plans that are comparable to or exceeding clinically approved and fixed-weight plans, in terms of dose homogeneity for the clinical target volume (CTV) and sparing of organs at risk (OARs). The study demonstrates the potential use of LLMs in SIBT planning automation.

physics.med-ph↗

arXiv2024

ReverseNER: A Self-Generated Example-Driven Framework for Zero-Shot Named Entity Recognition with Large Language Models

This paper presents ReverseNER, a method aimed at overcoming the limitation of large language models (LLMs) in zero-shot named entity recognition (NER) tasks, arising from their reliance on pre-provided demonstrations. ReverseNER tackles this challenge by constructing a reliable example library composed of dozens of entity-labeled sentences, generated through the reverse process of NER. Specifically, while conventional NER methods label entities in a sentence, ReverseNER features reversing the process by using an LLM to generate entities from their definitions and subsequently expand them into full sentences. During the entity expansion process, the LLM is guided to generate sentences by replicating the structures of a set of specific \textsl{feature sentences}, extracted from the task sentences by clustering. This expansion process produces dozens of entity-labeled task-relevant sentences. After constructing the example library, the method selects several semantically similar entity-labeled examples for each task sentence as references to facilitate the LLM's entity recognition. We also propose an entity-level self-consistency scoring mechanism to improve NER performance with LLMs. Experiments show that ReverseNER significantly outperforms other zero-shot NER methods with LLMs, marking a notable improvement in NER for domains without labeled data, while declining computational resource consumption.

cs.CL↗

arXiv2023

Coherent Dynamics of Charge Carriers in γ-InSe Revealed by Ultrafast Spectroscopy

For highly efficient ultrathin solar cells, layered indium selenide (InSe), a van der Waals solid, has shown a great promise. In this paper, we study the coherent dynamics of charge carriers generation in γ-InSe single crystals. We employ ultrafast transient absorption spectroscopy to examine the dynamics of hot electrons after resonant photoexcitation. To study the effect of excess kinetic energy of electrons after creating A exciton (VB1 to CB transition), we excite the sample with broadband pulses centered at 600, 650, 700 and 750 nm, respectively. We analyze the relaxation and recombination dynamics in γ-InSe by global fitting approach. Five decay associated spectra with their associated lifetimes are obtained, which have been assigned to intraband vibrational relaxation and interband recombination processes. We extract characteristic carrier thermalization times from 1 to 10 ps. To examine the coherent vibrations accompanying intraband relaxation dynamics, we analyze the kinetics by fitting to exponential functions and the obtained residuals are further processed for vibrational analysis. A few key phonon coherences are resolved and ab-initio quantum calculations reveal the nature of the associated phonons. The wavelet analysis is employed to study the time evolution of the observed coherences, which show that the low-frequency coherences last for more than 5 ps. Associated calculations reveal that the contribution of the intralayer phonon modes is the key determining factor for the scattering between free electrons and lattice. Our results provide fundamental insights into the photophysics in InSe and help to unravel their potential for high-performance optoelectronic devices.

cond-mat.mtrl-sci↗

arXiv2022

Accelerate Three-Dimensional Generative Adversarial Networks Using Fast Algorithm

Three-dimensional generative adversarial networks (3D-GAN) have attracted widespread attention in three-dimension (3D) visual tasks. 3D deconvolution (DeConv), as an important computation of 3D-GAN, significantly increases computational complexity compared with 2D DeConv. 3D DeConv has become a bottleneck for the acceleration of 3D-GAN. Previous accelerators suffer from several problems, such as large memory requirements and resource underutilization. To handle the above issues, a fast algorithm for 3D DeConv (F3DC) is proposed in this paper. F3DC applies a fast algorithm to reduce the number of multiplications and achieves a significant algorithmic strength reduction. Besides, F3DC removes the extra memory requirement for overlapped partial sums and avoids computational imbalance to fully utilize resources. Moreover, we design an F3DC-based hardware architecture, which consists of four fast processing units (FPUs). Each FPU includes a pre-process module, a EWMM module and a post-process module for F3DC transformation. By implementing our design on the Xilinx VC709 platform for 3D-GAN, we achieve a throughput up to 1700 GOPS and 4$\times$ computational efficiency improvement compared with prior works.

eess.SP↗