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Handi Deng

Publications and source records attributed to Handi Deng.

3 recordsLinked to original sources

RF heating-enhanced photoacoustic tomography

Photoacoustic tomography (PAT) and thermoacoustic tomography (TAT) both leverage acoustic signals generated by electromagnetic absorption to noninvasively image deep tissues. PAT operates by detecting optical absorption, whereas TAT targets radiofrequency (RF) absorption, providing complementary information on tissue composition and structure. Combining these modalities into a single system promises richer contrast but remains difficult due to the expense and complexity of the RF source. Here, we show that PAT can be integrated with a low-cost RF heater and used to image both optical and RF absorption in tissue phantoms. RF Heating-Enhanced Photoacoustic Tomography (HEPAT) maps RF absorption via temperature-dependent changes in thermomechanical properties, which enables the use of slow, inexpensive RF subsystems and provides an additional layer of contrast. HEPAT therefore provides distinct, complementary contrast relative to existing photoacoustic imaging systems, expanding specificity and diagnostic power while opening new avenues for studying temperature-related tissue phenomena.

physics.optics

End-to-End Hardware Modeling and Sensitivity Optimization of Photoacoustic Signal Readout Chains

The sensitivity of the acoustic detection subsystem in photoacoustic imaging (PAI) critically affects image quality. However, previous studies often focused only on front-end acoustic components or back-end electronic components, overlooking end-to-end coupling among the transducer, cable, and receiver. This work develops a complete analytical model for system-level sensitivity optimization based on the Krimholtz, Leedom, and Matthaei (KLM) model. The KLM model is rederived from first principles of linear piezoelectric constitutive equations, 1D wave equations and transmission line theory to clarify its physical basis and applicable conditions. By encapsulating the acoustic components into a controlled voltage source and extending the model to include lumped-parameter representations of cable and receiver, an end-to-end equivalent circuit is established. Analytical expressions for the system transfer functions are derived, revealing the coupling effects among key parameters such as transducer element area (EA), cable length (CL), and receiver impedance (RI). Experimental results validate the model with an average error below 5%. Additionally, a low-frequency tailing phenomenon arising from exceeding the 1D vibration assumption is identified and analyzed, illustrating the importance of understanding the model's applicable conditions and providing a potential pathway for artifact suppression. This work offers a comprehensive framework for optimizing detection sensitivity and improving image fidelity in PAI systems.

eess.SP

Streamlined Photoacoustic Image Processing with Foundation Models: A Training-Free Solution

Foundation models have rapidly evolved and have achieved significant accomplishments in computer vision tasks. Specifically, the prompt mechanism conveniently allows users to integrate image prior information into the model, making it possible to apply models without any training. Therefore, we propose a method based on foundation models and zero training to solve the tasks of photoacoustic (PA) image segmentation. We employed the segment anything model (SAM) by setting simple prompts and integrating the model's outputs with prior knowledge of the imaged objects to accomplish various tasks, including: (1) removing the skin signal in three-dimensional PA image rendering; (2) dual speed-of-sound reconstruction, and (3) segmentation of finger blood vessels. Through these demonstrations, we have concluded that deep learning can be directly applied in PA imaging without the requirement for network design and training. This potentially allows for a hands-on, convenient approach to achieving efficient and accurate segmentation of PA images. This letter serves as a comprehensive tutorial, facilitating the mastery of the technique through the provision of code and sample datasets.

cs.CV