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Hans-Michael Tautenhahn

Publications and source records attributed to Hans-Michael Tautenhahn.

3 recordsLinked to original sources

Retrieval-Augmented Generation of Ontologies from Relational Databases

Deriving OWL ontologies from relational database schemas supports semantic interoperability and downstream tasks such as knowledge graph population, ontology-based data access, graph-based learning, and automated reasoning. Existing approaches either require substantial expert effort or produce shallow ontologies that reflect the logical schema structure but fail to fully capture domain semantics. We present RIGOR (Retrieval-augmented Iterative Generation of RDB Ontologies), an LLM-driven pipeline that converts relational schemas into semantically rich OWL2DL ontologies with minimal human intervention. For each relational table, RIGOR generates a direct mapping to guarantee schema coverage, then enriches it via retrieval from three sources: relational schema context and documentation, external domain ontologies, and an ontology that grows incrementally as each validated fragment is integrated. A Gen-LLM produces provenance-annotated ontology fragments (delta ontologies), which are validated and, when needed, corrected by an independent Judge-LLM before integration. Guided by foreign-key constraints, the process iterates over relational tables until the full schema is covered. Experiments across three databases spanning two domains show that RIGOR consistently outperforms baseline methods across standard quality metrics while requiring no human oversight.

cs.DB

Insights into experimental evaluation of the non-fourier heat transfer model in biological tissues

A comprehensive understanding of heat transfer mechanisms in biological tissues is essential for the advancement of thermal therapeutic techniques and the development of accurate bioheat transfer models. Conventional models often fail to capture the inherently complex thermal behavior of biological media, necessitating more sophisticated approaches for experimental validation and parameter extraction. In this study, the Two-Dimensional Three-Phase Lag (TPL) heat transfer model, implemented via the finite difference method (FDM), was employed to extract key phase lag parameters characterizing heat conduction in bovine skin tissue. Experimental measurements were obtained using a 450 nm laser source and two non-contact infrared sensors. The influence of four critical parameters was systematically investigated: heat flux phase lag ($τ_{q}$), temperature gradient phase lag ($τ_θ$), thermal displacement coefficient ($k^*$), and thermal displacement phase lag ($τ_{v}$). A carefully designed experimental protocol was used to assess each parameter independently. The results revealed that the extracted phase lag values were substantially lower than those previously reported in the literature. This highlights the importance of high-precision measurements and the need to isolate each parameter during analysis. These findings contribute to the refinement of bioheat transfer models and hold potential for improving the efficacy and safety of clinical thermal therapies.

physics.bio-ph

Building up a model family for inflammations

The paper presents an approach for overcoming modeling problems of typical life science applications with partly unknown mechanisms and lacking quantitative data: A model family of reaction diffusion equations is built up on a mesoscopic scale and uses classes of feasible functions for reaction and taxis terms. The classes are found by translating biological knowledge into mathematical conditions and the analysis of the models further constrains the classes. Numerical simulations allow comparing single models out of the model family with available qualitative information on the solutions from observations. The method provides insight into a hierarchical order of the mechanisms. The method is applied to the clinics for liver inflammation such as metabolic dysfunction-associated steatohepatitis (MASH) or viral hepatitis where reasons for the chronification of disease are still unclear and time- and space-dependent data is unavailable.

math.DS