Haobin Yuan | Searcharxiv

arXiv2025

Overview of CHIP 2025 Shared Task 2: Discharge Medication Recommendation for Metabolic Diseases Based on Chinese Electronic Health Records

Discharge medication recommendation plays a critical role in ensuring treatment continuity, preventing readmission, and improving long-term management for patients with chronic metabolic diseases. This paper present an overview of the CHIP 2025 Shared Task 2 competition, which aimed to develop state-of-the-art approaches for automatically recommending appro-priate discharge medications using real-world Chinese EHR data. For this task, we constructed CDrugRed, a high-quality dataset consisting of 5,894 de-identified hospitalization records from 3,190 patients in China. This task is challenging due to multi-label nature of medication recommendation, het-erogeneous clinical text, and patient-specific variability in treatment plans. A total of 526 teams registered, with 167 and 95 teams submitting valid results to the Phase A and Phase B leaderboards, respectively. The top-performing team achieved the highest overall performance on the final test set, with a Jaccard score of 0.5102, F1 score of 0.6267, demonstrating the potential of advanced large language model (LLM)-based ensemble systems. These re-sults highlight both the promise and remaining challenges of applying LLMs to medication recommendation in Chinese EHRs. The post-evaluation phase remains open at https://tianchi.aliyun.com/competition/entrance/532411/.

cs.CL↗

arXiv2025

MediRec: Enhancing Chinese Medication Recommendation with Explainable Clinical Reasoning

Large language models (LLMs) have shown strong potential for clinical decision support through their advanced language understanding and reasoning capabilities. However, their application to Chinese clinical medication recommendation remains largely unexplored. Existing approaches are primarily developed on English electronic health record datasets and focus on coarse-grained medication code prediction, offering limited support for interpretable clinical decision-making. In this work, we propose MediRec, an explainable LLM-based framework for Chinese medication recommendation from electronic health records. MediRec combines clinically grounded reasoning-chain distillation with reinforcement learning to improve both recommendation accuracy and interpretability. Comprehensive experiments on a Chinese medication recommendation benchmark show that MediRec achieves strong performance, with an F1 score of 0.5813 and a Jaccard score of 0.4626. Further analyses indicate that MediRec generates clinically plausible recommendations with transparent reasoning, demonstrating its effectiveness for explainable medication decision support in Chinese healthcare settings.

cs.CL↗