arXiv subjects

Haochen Yang

Publications and source records attributed to Haochen Yang.

16 recordsLinked to original sources

arXiv2026

Evaluating LLM Robustness Under Domain-Specific Prompt Perturbations in Public Health Applications

Large language models (LLMs) are increasingly applied in public health applications, yet their robustness to non-clinical user inputs remains underexplored. We propose a domain specific robustness benchmark that evaluates LLMs under two perturbation types that commonly arise when non-clinical users interact with health AI systems: misinformation framing (MF), where prompt might be injected by false health claims, and layperson rewriting (LR), where patients describe symptoms in everyday language rather than medical terminology. Our goal is to evaluate the stability of LLMs under these perturbation. Experiments show that MF degrades accuracy by 7.2 pp on average with prediction flip rates of 9-38 percent, even when claims are explicitly labelled as unsupported; LR causes only 1.4 pp degradation. These findings highlight two distinct deployment risks in public health settings: models may produce incorrect outputs when users unintentionally carry misinformation into their queries, and may misinterpret clinically relevant details when patients use informal language. Both risks call for perturbation-aware robustness evaluation beyond clean baseline benchmark

cs.CY↗

arXiv2026

OptSkills: Learning Generalizable Optimization Skills from Problem Archetypes via Cluster-Based Distillation

Leveraging Large Language Models (LLMs) to automatically formulate and solve optimization problems from natural language has emerged as an efficient paradigm for automated optimization. However, existing methods still exhibit limited generalization: they are sensitive to superficial narrative variations, reuse experience mainly at the case level, and struggle to adapt to shifted or emerging problem types. We propose OptSkills, an archetype-centric skill learning and reasoning agent system for optimization modeling and solving. To improve robust generalization, our system clusters problems by their underlying archetypes rather than surface narratives. To improve in-distribution generalization, it explores diverse modeling paradigms and solver configurations within each cluster, then distills successful trajectories into reusable workflow-level skills. To improve out-of-distribution generalization, it refines existing skills or expands the skill library using newly obtained trajectories. Our system achieves a state-of-the-art micro-averaged accuracy of 68.27% on datasets encompassing diverse problem types and scenarios. In addition, on MIPLIB-NL, a highly challenging large-scale and high-dimensional benchmark, it achieves 26.91% accuracy, outperforming DeepSeek-V3.2-Thinking by 4.53%. After skill learning on Nano-CO, it reaches 72.79% on the OOD NLCO benchmark. Code and skills are available at https://github.com/fujiwaranoM0kou/OptSkills.

cs.AI↗

arXiv2026

Optimal Transport for LLM Reward Modeling from Noisy Preference

Reward models are fundamental to Reinforcement Learning from Human Feedback (RLHF), yet real-world datasets are inevitably corrupted by noisy preference. Conventional training objectives tend to overfit these errors, while existing denoising approaches often rely on homogeneous noise assumptions that fail to capture the complexity of linguistic preferences. To handle these challenges, we propose SelectiveRM, a framework grounded in optimal transport. We first devise a Joint Consistency Discrepancy to align the distribution of model predictions with preference data. Furthermore, to address the limitation of strict mass conservation which compels the model to fit outliers, we incorporate a Mass Relaxation mechanism via partial transport. This enables the autonomous exclusion of samples with noisy preference that contradict semantic consistency. Theoretically, we demonstrate that SelectiveRM optimizes a tighter upper bound on the unobserved clean risk. Extensive experiments validate that our approach significantly outperforms state-of-the-art baselines across diverse benchmarks.

cs.LG↗

arXiv2026

Unsupervised Multi-agent and Single-agent Perception from Cooperative Views

The LiDAR-based multi-agent and single-agent perception has shown promising performance in environmental understanding for robots and automated vehicles. However, there is no existing method that simultaneously solves both multi-agent and single-agent perception in an unsupervised way. By sharing sensor data between multiple agents via communication, this paper discovers two key insights: 1) Improved point cloud density after the data sharing from cooperative views could benefit unsupervised object classification, 2) Cooperative view of multiple agents can be used as unsupervised guidance for the 3D object detection in the single view. Based on these two discovered insights, we propose an Unsupervised Multi-agent and Single-agent (UMS) perception framework that leverages multi-agent cooperation without human annotations to simultaneously solve multi-agent and single-agent perception. UMS combines a learning-based Proposal Purifying Filter to better classify the candidate proposals after multi-agent point cloud density cooperation, followed by a Progressive Proposal Stabilizing module to yield reliable pseudo labels by the easy-to-hard curriculum learning. Furthermore, we design a Cross-View Consensus Learning to use multi-agent cooperative view to guide detection in single-agent view. Experimental results on two public datasets V2V4Real and OPV2V show that our UMS method achieved significantly higher 3D detection performance than the state-of-the-art methods on both multi-agent and single-agent perception tasks in an unsupervised setting.

cs.CV↗

arXiv2026

DarkDriving: A Real-World Day and Night Aligned Dataset for Autonomous Driving in the Dark Environment

The low-light conditions are challenging to the vision-centric perception systems for autonomous driving in the dark environment. In this paper, we propose a new benchmark dataset (named DarkDriving) to investigate the low-light enhancement for autonomous driving. The existing real-world low-light enhancement benchmark datasets can be collected by controlling various exposures only in small-ranges and static scenes. The dark images of the current nighttime driving datasets do not have the precisely aligned daytime counterparts. The extreme difficulty to collect a real-world day and night aligned dataset in the dynamic driving scenes significantly limited the research in this area. With a proposed automatic day-night Trajectory Tracking based Pose Matching (TTPM) method in a large real-world closed driving test field (area: 69 acres), we collected the first real-world day and night aligned dataset for autonomous driving in the dark environment. The DarkDriving dataset has 9,538 day and night image pairs precisely aligned in location and spatial contents, whose alignment error is in just several centimeters. For each pair, we also manually label the object 2D bounding boxes. DarkDriving introduces four perception related tasks, including low-light enhancement, generalized low-light enhancement, and low-light enhancement for 2D detection and 3D detection of autonomous driving in the dark environment. The experimental results show that our DarkDriving dataset provides a comprehensive benchmark for evaluating low-light enhancement for autonomous driving and it can also be generalized to enhance dark images and promote detection in some other low-light driving environment, such as nuScenes.The code and dataset will be publicly available at https://github.com/DriveMindLab/DarkDriving-ICRA-2026.

cs.CV↗

arXiv2026

Topological shape transform for thymus structures

The Euler characteristic transform (ECT) is an emerging and powerful framework within topological data analysis for quantifying the geometry of shape. The applicability of ECT has been limited due to its sensitivity to noisy data. Here, we introduce SampEuler, a novel ECT-based shape descriptor designed to achieve enhanced robustness to perturbations. We provide a theoretical analysis establishing the stability of SampEuler and validate these properties empirically through pairwise similarity analyses on a benchmark dataset and showcase it on a thymus dataset. The thymus is a primary lymphoid organ that is essential for the maturation and selection of self-tolerant T cells, and within the thymus, thymic epithelial cells are organized in complex three-dimensional architectures, yet the principles governing their formation, functional organization, and remodeling during age-related involution remain poorly understood. Addressing these questions requires robust and informative shape descriptors capable of capturing subtle architectural changes across developmental stages. We develop and apply SampEuler to a newly generated two-dimensional imaging dataset of mouse thymi spanning multiple age groups, where SampEuler outperforms both persistent homology--based methods and deep learning models in detecting subtle, localized morphological differences associated with aging. To facilitate interpretation, we develop a vectorization and visualization framework for SampEuler, which preserves rich morphological information and enables identification of structural features that distinguish thymi across age groups. Collectively, our results demonstrate that SampEuler provides a robust and interpretable approach for quantifying thymic architecture and reveals age-dependent structural changes that offer new insights into thymic organization and involution.

math.AT↗

arXiv2025

Reducing Belief Deviation in Reinforcement Learning for Active Reasoning

Active reasoning requires large language model (LLM) agents to interact with external sources and strategically gather information to solve problems in multiple turns. Central to this process is belief tracking: maintaining an accurate representation of the underlying state and uncertainty in understanding and solving the problem. However, due to limited reasoning capabilities, LLM-based agents often suffer belief deviation: their internal beliefs drift from the true problem state, leading to loss of state awareness and uninformative or repetitive actions. Once this happens, errors compound in the trajectories used for reinforcement learning (RL), leading to misattributed credits and limited exploration. To address this issue, we propose to track belief deviation and develop $\mathbf{T^3}$, a simple yet principled method that detects excessive deviation and truncates training trajectories to suppress uninformative tail effects. Hence, $\mathbf{T^3}$ preserves credits for informative prefixes and systematically improves policy optimization. Across 5 challenging tasks, $\mathbf{T^3}$ consistently enhances training stability and yields performance gains of up to 30 points while cutting token cost by up to 34%. These results highlight belief control as a key principle for building robust LLM agents capable of active reasoning.

cs.AI↗

arXiv2025

Virtual Cells: From Conceptual Frameworks to Biomedical Applications

The challenge of translating vast, multimodal biological data into predictive and mechanistic understanding of cellular function is a central theme in modern biology. Virtual cells, or digital cellular twins, have emerged as a critical paradigm to meet this challenge by creating integrative computational models of cellular processes. This review synthesizes the evolution and current state of the virtual cell, from foundational mechanistic frameworks like the Virtual Cell that employ deterministic and stochastic simulations to the recent transformative impact of artificial intelligence and foundation models. We examine the core technological pillars required to build these models, including the integration of various data types, such as single-cell and spatial omics, the spectrum of modeling approaches, and the bioengineering principles that connect simulation to application. We further discuss key applications, frameworks for model benchmarking and validation, and the significant hurdles that remain, including computational scalability, parameter inference, and ethical considerations, which provides a roadmap for development of predictive virtual cells that promise to revolutionize biomedical research and clinical practice.

q-bio.QM↗

arXiv2025

Team Westwood Solution for MIDOG 2025 Challenge: An Ensemble-CNN-Based Approach For Mitosis Detection And Classification

This abstract presents our solution (Team Westwood) for mitosis detection and atypical mitosis classification in the MItosis DOmain Generalization (MIDOG) 2025 challenge. For mitosis detection, we trained an nnUNetV2 for initial mitosis candidate screening with high sensitivity, followed by a random forest classifier ensembling predictions of three convolutional neural networks (CNNs): EfficientNet-b3, EfficientNet-b5, and EfficientNetV2-s. For the atypical mitosis classification, we trained another random forest classifier ensembling the predictions of three CNNs: EfficientNet-b3, EfficientNet-b5, and InceptionV3. On the preliminary test set, our solution achieved an F1 score of 0.7450 for track 1 mitosis detection, and a balanced accuracy of 0.8722 for track 2 atypical mitosis classification. On the final test set, our solution achieved an F1 score of 0.6972 for track 1 mitosis detection, and a balanced accuracy of 0.8242 for track 2 atypical mitosis classification.

eess.IV↗

arXiv2025

From Mind to Machine: The Rise of Manus AI as a Fully Autonomous Digital Agent

Manus AI is a general-purpose AI agent introduced in early 2025, marking a significant advancement in autonomous artificial intelligence. Developed by the Chinese startup Monica.im, Manus is designed to bridge the gap between "mind" and "hand" - combining the reasoning and planning capabilities of large language models with the ability to execute complex, end-to-end tasks that produce tangible outcomes. This paper presents a comprehensive overview of Manus AI, exploring its core technical architecture, diverse applications across sectors such as healthcare, finance, manufacturing, robotics, and gaming, as well as its key strengths, current limitations, and future potential. Positioned as a preview of what lies ahead, Manus AI represents a shift toward intelligent agents that can translate high-level intentions into real-world actions, heralding a new era of human-AI collaboration.

cs.AI↗

arXiv2025

Sample-Efficient Reinforcement Learning from Human Feedback via Information-Directed Sampling

We study the problem of reinforcement learning from human feedback (RLHF), a critical problem in training large language models, from a theoretical perspective. Our main contribution is the design of novel sample-efficient RLHF algorithms based on information-directed sampling (IDS), an online decision-making principle inspired by information theory. Our algorithms maximize the sum of the value function and a mutual information term that encourages exploration of the unknown environment (which quantifies the information gained about the environment through observed human feedback data). To tackle the challenge of large state spaces and improve sample efficiency, we construct a simplified \emph{surrogate environment} and introduce a novel distance measure (named the \emph{$\ell_g$-distance}), enabling our IDS-based algorithm to achieve a Bayesian regret upper bound of order $O(H^{\frac{3}{2}}\sqrt{\log(K(\epsilon)) T})$, where $H$ is the episode length, $T$ is the number of episode and $K(\epsilon)$ is related to the covering number of the environment. Specializing to the tabular settings, this regret bound is of order $\tilde{O}(H^2\sqrt{SAT})$, where $S$ and $A$ are the numbers of states and actions. Finally, we propose an Approximate-IDS algorithm that is computationally more efficient while maintaining nearly the same sample efficiency. The design principle of this approximate algorithm is not only effective in RLHF settings but also applicable to the standard RL framework. Moreover, our work showcases the value of information theory in reinforcement learning and in the training of large language models.

cs.LG↗

arXiv2024

Stealthy Multi-Task Adversarial Attacks

Deep neural networks are highly vulnerable to adversarial perturbations, raising serious safety concerns in the real-world systems. While prior work mainly explores single-task attacks or jointly degrading all tasks in multi-task models, practical scenarios often demand more selective and stealthy attack strategies. To address this challenge, we propose Stealthy Multi-Task Adversarial Attack (SMTA$^{2}$), a novel framework that selectively degrades a targeted task while strictly preserving the performance of non-targeted tasks. We formulate this objective as a constrained multi-objective optimization problem and design task-aware adversarial perturbations that maximize degradation on the targeted task without causing collateral damage on non-targeted tasks. To enhance practicality, we further introduce an automated loss-weight tuning strategy that dynamically balances attack and preservation objectives. Experiments on two multi-task benchmarks NYUv2 and Cityscapes demonstrate that SMTA$^{2}$ achieves strong attack performance on targeted tasks while maintaining non-targeted tasks intact on both undefended and adversarially trained models, establishing the first systematic framework for stealthy and selective multi-task attack framework.

cs.CR↗

arXiv2024

CATP: Cross-Attention Token Pruning for Accuracy Preserved Multimodal Model Inference

In response to the rising interest in large multimodal models, we introduce Cross-Attention Token Pruning (CATP), a precision-focused token pruning method. Our approach leverages cross-attention layers in multimodal models, exemplified by BLIP-2, to extract valuable information for token importance determination. CATP employs a refined voting strategy across model heads and layers. In evaluations, CATP achieves up to 12.1X higher accuracy compared to existing token pruning methods, addressing the trade-off between computational efficiency and model precision.

cs.CL↗

arXiv2022

Can Machines Imitate Humans? Integrative Turing-like tests for Language and Vision Demonstrate a Narrowing Gap

As AI becomes increasingly embedded in daily life, ascertaining whether an agent is human is critical. We systematically benchmark AI's ability to imitate humans in three language tasks (image captioning, word association, conversation) and three vision tasks (color estimation, object detection, attention prediction), collecting data from 636 humans and 37 AI agents. Next, we conducted 72,191 Turing-like tests with 1,916 human judges and 10 AI judges. Current AIs are approaching the ability to convincingly impersonate humans and deceive human judges in both language and vision. Even simple AI judges outperformed humans in distinguishing AI from human responses. Imitation ability showed minimal correlation with conventional AI performance metrics, suggesting that passing as human is an important independent evaluation criterion. The large-scale Turing datasets and metrics introduced here offer valuable benchmarks for assessing human-likeness in AI and highlight the importance of rigorous, quantitative imitation tests for AI development.

cs.CV↗

arXiv2021

Model-based Pre-clinical Trials for Medical Devices Using Statistical Model Checking

Clinical trials are considered as the golden standard for medical device validation. However, many sacrifices have to be made during the design and conduction of the trials due to cost considerations and partial information, which may compromise the significance of the trial results. In this paper, we proposed a model-based pre-clinical trial framework using statistical model checking. Physiological models represent disease mechanism, which enable automated adjudication of simulation results. Sampling of the patient parameters and hypothesis testing are performed by statistical model checker. The framework enables a broader range of hypothesis to be tested with guaranteed statistical significance, which are useful complements to the clinical trials. We demonstrated our framework with a pre-clinical trial on implantable cardioverter defibrillators.

stat.AP↗

arXiv2021

Calibrating and Improving Graph Contrastive Learning

Graph contrastive learning algorithms have demonstrated remarkable success in various applications such as node classification, link prediction, and graph clustering. However, in unsupervised graph contrastive learning, some contrastive pairs may contradict the truths in downstream tasks and thus the decrease of losses on these pairs undesirably harms the performance in the downstream tasks. To assess the discrepancy between the prediction and the ground-truth in the downstream tasks for these contrastive pairs, we adapt the expected calibration error (ECE) to graph contrastive learning. The analysis of ECE motivates us to propose a novel regularization method, Contrast-Reg, to ensure that decreasing the contrastive loss leads to better performance in the downstream tasks. As a plug-in regularizer, Contrast-Reg effectively improves the performance of existing graph contrastive learning algorithms. We provide both theoretical and empirical results to demonstrate the effectiveness of Contrast-Reg in enhancing the generalizability of the Graph Neural Network(GNN) model and improving the performance of graph contrastive algorithms with different similarity definitions and encoder backbones across various downstream tasks.

cs.LG↗