arXiv subjects

Haocheng Tang

Publications and source records attributed to Haocheng Tang.

12 recordsLinked to original sources

arXiv2026

RIFT: Residual-Informed Flow Transfer for One-Step Generative Video Compression

Recent advances in video generation have enabled generative video compression to reconstruct details lost during coding using pretrained spatiotemporal priors. However, a substantial gap remains between codec-induced degradation and the perturbation trajectories learned by flow-matching models. In this paper, we identify a compression-dependent directional mismatch that degradation-strength-based timestep calibration alone cannot resolve. Compressed latents remain strongly aligned across codec operating points, while their reconstruction residuals vary substantially in magnitude and direction. To bridge this gap, we propose RIFT, a Residual-Informed Flow Transfer framework for one-step generative video compression. At its core, RIFT introduces a Residual Geometry Inducer (RGI) that converts the pretrained flow prediction into a content-adaptive restoration update using decoder-visible codec cues. RGI integrates flow-timestep conditioning with a learned full-band residual-strength estimate and content-conditioned direction and gain modulation, aligning the orientation and magnitude of the update with the compression-dependent residual geometry. Extensive experiments on three public video compression benchmarks show that RIFT outperforms competing generative video compression methods. The code is publicly available on RIFT.

cs.CV↗

arXiv2026

Rethinking Video Storage for AI Training: Breaking Cross-Frame Dependencies for Efficient Random Access

Large-scale AI training increasingly relies on massive video datasets with random temporal sampling patterns. However, existing video storage paradigms are optimized for sequential playback and employ sophisticated inter-frame reference structures to maximize compression efficiency. When applied to the random-sampling workloads of AI training, these paradigms face substantial decoding-efficiency bottlenecks. Workarounds such as independent JPEG frames and short groups of pictures (GOPs) reduce decoding work at the cost of larger storage and transfer volumes. In this paper, we identify two sources of decode amplification: sequential reconstruction of unrelated frames and reconstruction of the reference chains required by sampled targets. We address both sources by co-designing the decoding schedule and video reference structure. Dependency-aware sparse decoding reconstructs only requested frames and their required references, skipping unrelated reconstruction without transcoding the source videos. Optional offline Dependency-Decoupled Random Access (DDRA) encoding further reduces reference reconstruction by restricting each interior frame to two bounding intra-coded anchors. Together, sparse decoding and DDRA retain inter-frame prediction while bounding reconstruction to at most three frames per requested target, independent of the intra period. Experiments on a large-scale robotics corpus show that, at comparable reconstruction quality, our method achieves $1.45\times$ the loading throughput of LeRobot v3 with 58.7% less media payload.

cs.CV↗

arXiv2026

MeanFlowAdvantage: Stable Reward Fine-Tuning for Few-Step Average-Velocity Generators

MeanFlow enables efficient few-step generation by predicting interval-average velocities, but this representation creates a mismatch for reward fine-tuning: existing advantage-based objectives are typically defined on instantaneous velocities or equivalent $x_0$-space predictions, whereas inference directly uses the learned average-velocity map. We introduce MeanFlowAdvantage, a signed advantage-weighted least-squares objective for average-velocity generators. Our key construction uses a shared, detached MeanFlow derivative correction to express the reward objective in prediction space while making rollout and reference regularization exact penalties on the average-velocity network deployed at inference. The resulting formulation preserves MeanFlow's native few-step sampler and provides a direct mechanism for transferring reward improvements to the deployed flow map. On SD3.5-Medium, MeanFlowAdvantage improves all eight reported metrics over the matched four-step MeanFlowNFT baseline and, with only four NFEs, matches or exceeds the 40-step DiffusionNFT baseline on six of eight metrics. The same objective also transfers to DNA promoter design, where it supports both teacher-free on-policy RL for a generator defined on a manifold and teacher-guided reward-graded distillation, with the latter yielding the lowest one-step Sei profile MSE among the compared configurations.

cs.AI↗

arXiv2026

Where Should Physics Enter a Molecular Crystal Generator?

Generative models make molecular crystal structure prediction fast, but their samples still exhibit geometric and packing violations. Physics can be introduced during training, post-training, or inference, yet these choices are rarely compared with the generator and physical signal held fixed. We introduce CrystAF, an all-atom crystal flow-map generation model, and use it with the UMA interatomic potential to systematically study where physics should enter. Post-training learns physical preferences directly into CrystAF, improving molecular validity and crystal packing while leaving sampling unchanged: physics is paid for once during training rather than repeatedly at deployment. In contrast, UMA relaxation is effective at repairing local clashes but makes generation 6--26$\times$ slower, while learning from relaxed targets provides little benefit. These routes are complementary rather than competing. Physics-informed post-training first shifts the generated distribution toward more physically reasonable structures, after which inexpensive inference-time corrections further remove clashes and restore stereochemistry that the generator cannot represent. Importantly, the same post-training strategy also improves the multi-step all-atom Clari-M and rigid-body MolCrystalFlow generators, demonstrating transfer across architectures and representations. Together, our results suggest a simple principle: learn reusable physical alignment into the generator, and reserve inference-time physics for residual constraints that are better corrected than learned.

q-bio.BM↗

arXiv2026

Localize, Then Reason: Visual Latent Structural Reasoning for Molecular Properties and Edits

Local chemical perception and property reasoning are both essential for understanding how molecular structure determines properties. Current LLM-based chemical reasoning methods either receive SMILES/molecular images together with descriptions of local motifs, or reason directly from molecular images. Neither approach enables the model to focus on chemically meaningful regions before reasoning. To address this gap, we propose Visual Latent Structural Reasoning (VLSR), an end-to-end framework that jointly learns localization and reasoning from molecular images. Central to our approach is a localize-then-reason strategy. VLSR first learns to locate chemically meaningful regions in a molecular image. It then reasons about their property effects in a compact latent workspace before producing the final answer. Under the same inference setup, this design achieves 9.6X higher throughput than a comparable textual-reasoning baseline.

cs.CL↗

arXiv2026

Learning Mechanistic Reasoning for Chemical Reactions with Large Language Models

Reaction mechanisms consist of the step-by-step sequences of elementary reactions that explain chemical transformations. Learning the mechanism logic is therefore essential for enhancing the fundamental chemical intelligence of large language models (LLMs). The stepwise deduction of reaction mechanism aligns naturally with the reasoning paradigms of reasoning LLMs. However, current chemical LLMs primarily emphasize coarse-grained name reactions for product prediction and retrosynthesis, often leading to physical inconsistencies and hallucinations. In contrast, specialized small-scale generative models for mechanism inference typically suffer from restricted generalization capacity across diverse chemical spaces. To overcome these limitations, we built a novel, large-scale reasoning dataset of reaction mechanisms. Furthermore, we established the FukuyamaBench, a difficult benchmark derived from Fukuyama's Advanced Organic Reaction Mechanism book, to rigorously evaluate model performance on hierarchical mechanism reasoning. Our fine-tuned Qwen3-30B-A3B achieves 8.3% exact pathway match on FukuyamaBench Set~A, surpassing the specialized FlowER model (5.1%), demonstrating that mechanism-aware training substantially enhances chemical reasoning in language models.

cs.LG↗

arXiv2026

Boosting Neural Video Codec via Scale-Driven Online Flow Refinement

Although state-of-the-art neural video codecs (NVCs) have achieved remarkable performance, they suffer from limited generalization when encountering complex motion patterns unseen during training. To bridge this domain gap without the expensive cost of online fine-tuning, we propose a Training-Free Scale-Driven Online Flow Refinement (SOFR) method. Serving as a plug-and-play module, SOFR integrates motion information from coarse and fine scales and dynamically fuses them according to warping accuracy, effectively rectifying motion estimation errors with negligible computational overhead. Furthermore, we design a rate-aware strategy that selects different dynamic fusion strategies according to bitrate modes, and employs a reliability check based on warping error to ensure robustness. Extensive experiments on the USTC-TD dataset verify the effectiveness and generalization of SOFR across various NVC frameworks, including DCVC-SDD, DCVC-FM, and EHVC. Notably, it brings an average of 2.84% and 4.05% bitrate savings in terms of PSNR and MS-SSIM, respectively, to DCVC-FM with negligible coding time increase. Our code is available at https://github.com/SunnyMass/SOFR.

cs.CV↗

arXiv2026

Learning Structure, Energy, and Dynamics: A Survey of Artificial Intelligence for Protein Dynamics

Protein dynamics underlie many biological functions, yet remain difficult to characterize due to the high computational cost of molecular dynamics simulations and the scarcity of dynamic structural data. This survey reviews recent advances in artificial intelligence for protein dynamics from three perspectives: learning from structural ensembles and trajectories, learning from physical energy signals, and learning to accelerate molecular simulations. We summarize representative methods for conformation ensemble generation, trajectory generation, Boltzmann generators, physics-aware adaptation, machine learning potentials, coarse-grained modeling, and collective variable discovery. We further discuss available datasets and key open challenges, such as scalability, thermodynamic consistency, kinetic fidelity, and integration with experimental constraints.

q-bio.BM↗

arXiv2026

Fine-tuning DeepSeek-OCR-2 for Molecular Structure Recognition

Optical Chemical Structure Recognition (OCSR) is critical for converting 2D molecular diagrams from printed literature into machine-readable formats. While Vision-Language Models have shown promise in end-to-end OCR tasks, their direct application to OCSR remains challenging, and direct full-parameter supervised fine-tuning often fails. In this work, we adapt DeepSeek-OCR-2 for molecular optical recognition by formulating the task as image-conditioned SMILES generation. To overcome training instabilities, we propose a two-stage progressive supervised fine-tuning strategy: starting with parameter-efficient LoRA and transitioning to selective full-parameter fine-tuning with split learning rates. We train our model on a large-scale corpus combining synthetic renderings from PubChem and realistic patent images from USPTO-MOL to improve coverage and robustness. Our fine-tuned model, MolSeek-OCR, demonstrates competitive capabilities, achieving exact matching accuracies comparable to the best-performing image-to-sequence model. However, it remains inferior to state-of-the-art image-to-graph modelS. Furthermore, we explore reinforcement-style post-training and data-curation-based refinement, finding that they fail to improve the strict sequence-level fidelity required for exact SMILES matching.

cs.CV↗

arXiv2026

Parallax to Align Them All: An OmniParallax Attention Mechanism for Distributed Multi-View Image Compression

Multi-view image compression (MIC) aims to achieve high compression efficiency by exploiting inter-image correlations, playing a crucial role in 3D applications. As a subfield of MIC, distributed multi-view image compression (DMIC) offers performance comparable to MIC while eliminating the need for inter-view information at the encoder side. However, existing methods in DMIC typically treat all images equally, overlooking the varying degrees of correlation between different views during decoding, which leads to suboptimal coding performance. To address this limitation, we propose a novel $\textbf{OmniParallax Attention Mechanism}$ (OPAM), which is a general mechanism for explicitly modeling correlations and aligned features between arbitrary pairs of information sources. Building upon OPAM, we propose a Parallax Multi Information Fusion Module (PMIFM) to adaptively integrate information from different sources. PMIFM is incorporated into both the joint decoder and the entropy model to construct our end-to-end DMIC framework, $\textbf{ParaHydra}$. Extensive experiments demonstrate that $\textbf{ParaHydra}$ is $\textbf{the first DMIC method}$ to significantly surpass state-of-the-art MIC codecs, while maintaining low computational overhead. Performance gains become more pronounced as the number of input views increases. Compared with LDMIC, $\textbf{ParaHydra}$ achieves bitrate savings of $\textbf{19.72%}$ on WildTrack(3) and up to $\textbf{24.18%}$ on WildTrack(6), while significantly improving coding efficiency (as much as $\textbf{65}\times$ in decoding and $\textbf{34}\times$ in encoding).

cs.CV↗

arXiv2025

HGC-Avatar: Hierarchical Gaussian Compression for Streamable Dynamic 3D Avatars

Recent advances in 3D Gaussian Splatting (3DGS) have enabled fast, photorealistic rendering of dynamic 3D scenes, showing strong potential in immersive communication. However, in digital human encoding and transmission, the compression methods based on general 3DGS representations are limited by the lack of human priors, resulting in suboptimal bitrate efficiency and reconstruction quality at the decoder side, which hinders their application in streamable 3D avatar systems. We propose HGC-Avatar, a novel Hierarchical Gaussian Compression framework designed for efficient transmission and high-quality rendering of dynamic avatars. Our method disentangles the Gaussian representation into a structural layer, which maps poses to Gaussians via a StyleUNet-based generator, and a motion layer, which leverages the SMPL-X model to represent temporal pose variations compactly and semantically. This hierarchical design supports layer-wise compression, progressive decoding, and controllable rendering from diverse pose inputs such as video sequences or text. Since people are most concerned with facial realism, we incorporate a facial attention mechanism during StyleUNet training to preserve identity and expression details under low-bitrate constraints. Experimental results demonstrate that HGC-Avatar provides a streamable solution for rapid 3D avatar rendering, while significantly outperforming prior methods in both visual quality and compression efficiency.

cs.CV↗

arXiv2025

Auxiliary Discrminator Sequence Generative Adversarial Networks (ADSeqGAN) for Few Sample Molecule Generation

In this work, we introduce Auxiliary Discriminator Sequence Generative Adversarial Networks (ADSeqGAN), a novel approach for molecular generation in small-sample datasets. Traditional generative models often struggle with limited training data, particularly in drug discovery, where molecular datasets for specific therapeutic targets, such as nucleic acids binders and central nervous system (CNS) drugs, are scarce. ADSeqGAN addresses this challenge by integrating an auxiliary random forest classifier as an additional discriminator into the GAN framework, significantly improves molecular generation quality and class specificity. Our method incorporates pretrained generator and Wasserstein distance to enhance training stability and diversity. We evaluate ADSeqGAN across three representative cases. First, on nucleic acid- and protein-targeting molecules, ADSeqGAN shows superior capability in generating nucleic acid binders compared to baseline models. Second, through oversampling, it markedly improves CNS drug generation, achieving higher yields than traditional de novo models. Third, in cannabinoid receptor type 1 (CB1) ligand design, ADSeqGAN generates novel druglike molecules, with 32.8\% predicted actives surpassing hit rates of CB1-focused and general-purpose libraries when assessed by a target-specific LRIP-SF scoring function. Overall, ADSeqGAN offers a versatile framework for molecular design in data-scarce scenarios, with demonstrated applications in nucleic acid binders, CNS drugs, and CB1 ligands.

cs.LG↗