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Hechang Chen

Publications and source records attributed to Hechang Chen.

43 records · Page 3Linked to original sources

Data and Knowledge Co-driving for Cancer Subtype Classification on Multi-Scale Histopathological Slides

Artificial intelligence-enabled histopathological data analysis has become a valuable assistant to the pathologist. However, existing models lack representation and inference abilities compared with those of pathologists, especially in cancer subtype diagnosis, which is unconvincing in clinical practice. For instance, pathologists typically observe the lesions of a slide from global to local, and then can give a diagnosis based on their knowledge and experience. In this paper, we propose a Data and Knowledge Co-driving (D&K) model to replicate the process of cancer subtype classification on a histopathological slide like a pathologist. Specifically, in the data-driven module, the bagging mechanism in ensemble learning is leveraged to integrate the histological features from various bags extracted by the embedding representation unit. Furthermore, a knowledge-driven module is established based on the Gestalt principle in psychology to build the three-dimensional (3D) expert knowledge space and map histological features into this space for metric. Then, the diagnosis can be made according to the Euclidean distance between them. Extensive experimental results on both public and in-house datasets demonstrate that the D&K model has a high performance and credible results compared with the state-of-the-art methods for diagnosing histopathological subtypes. Code: https://github.com/Dennis-YB/Data-and-Knowledge-Co-driving-for-Cancer-Subtypes-Classification

cs.CV↗

The Sufficiency of Off-Policyness and Soft Clipping: PPO is still Insufficient according to an Off-Policy Measure

The popular Proximal Policy Optimization (PPO) algorithm approximates the solution in a clipped policy space. Does there exist better policies outside of this space? By using a novel surrogate objective that employs the sigmoid function (which provides an interesting way of exploration), we found that the answer is ``YES'', and the better policies are in fact located very far from the clipped space. We show that PPO is insufficient in ``off-policyness'', according to an off-policy metric called DEON. Our algorithm explores in a much larger policy space than PPO, and it maximizes the Conservative Policy Iteration (CPI) objective better than PPO during training. To the best of our knowledge, all current PPO methods have the clipping operation and optimize in the clipped policy space. Our method is the first of this kind, which advances the understanding of CPI optimization and policy gradient methods. Code is available at https://github.com/raincchio/P3O.

cs.LG↗

Distributional Reward Estimation for Effective Multi-Agent Deep Reinforcement Learning

Multi-agent reinforcement learning has drawn increasing attention in practice, e.g., robotics and automatic driving, as it can explore optimal policies using samples generated by interacting with the environment. However, high reward uncertainty still remains a problem when we want to train a satisfactory model, because obtaining high-quality reward feedback is usually expensive and even infeasible. To handle this issue, previous methods mainly focus on passive reward correction. At the same time, recent active reward estimation methods have proven to be a recipe for reducing the effect of reward uncertainty. In this paper, we propose a novel Distributional Reward Estimation framework for effective Multi-Agent Reinforcement Learning (DRE-MARL). Our main idea is to design the multi-action-branch reward estimation and policy-weighted reward aggregation for stabilized training. Specifically, we design the multi-action-branch reward estimation to model reward distributions on all action branches. Then we utilize reward aggregation to obtain stable updating signals during training. Our intuition is that consideration of all possible consequences of actions could be useful for learning policies. The superiority of the DRE-MARL is demonstrated using benchmark multi-agent scenarios, compared with the SOTA baselines in terms of both effectiveness and robustness.

cs.LG↗

Learning the Network of Graphs for Graph Neural Networks

Graph neural networks (GNNs) have achieved great success in many scenarios with graph-structured data. However, in many real applications, there are three issues when applying GNNs: graphs are unknown, nodes have noisy features, and graphs contain noisy connections. Aiming at solving these problems, we propose a new graph neural network named as GL-GNN. Our model includes multiple sub-modules, each sub-module selects important data features and learn the corresponding key relation graph of data samples when graphs are unknown. GL-GNN further obtains the network of graphs by learning the network of sub-modules. The learned graphs are further fused using an aggregation method over the network of graphs. Our model solves the first issue by simultaneously learning multiple relation graphs of data samples as well as a relation network of graphs, and solves the second and the third issue by selecting important data features as well as important data sample relations. We compare our method with 14 baseline methods on seven datasets when the graph is unknown and 11 baseline methods on two datasets when the graph is known. The results show that our method achieves better accuracies than the baseline methods and is capable of selecting important features and graph edges from the dataset. Our code will be publicly available at \url{https://github.com/Looomo/GL-GNN}.

cs.LG↗

A Coarse-to-fine Cascaded Evidence-Distillation Neural Network for Explainable Fake News Detection

Existing fake news detection methods aim to classify a piece of news as true or false and provide veracity explanations, achieving remarkable performances. However, they often tailor automated solutions on manual fact-checked reports, suffering from limited news coverage and debunking delays. When a piece of news has not yet been fact-checked or debunked, certain amounts of relevant raw reports are usually disseminated on various media outlets, containing the wisdom of crowds to verify the news claim and explain its verdict. In this paper, we propose a novel Coarse-to-fine Cascaded Evidence-Distillation (CofCED) neural network for explainable fake news detection based on such raw reports, alleviating the dependency on fact-checked ones. Specifically, we first utilize a hierarchical encoder for web text representation, and then develop two cascaded selectors to select the most explainable sentences for verdicts on top of the selected top-K reports in a coarse-to-fine manner. Besides, we construct two explainable fake news datasets, which are publicly available. Experimental results demonstrate that our model significantly outperforms state-of-the-art baselines and generates high-quality explanations from diverse evaluation perspectives.

cs.CL↗

Enhanced Doubly Robust Learning for Debiasing Post-click Conversion Rate Estimation

Post-click conversion, as a strong signal indicating the user preference, is salutary for building recommender systems. However, accurately estimating the post-click conversion rate (CVR) is challenging due to the selection bias, i.e., the observed clicked events usually happen on users' preferred items. Currently, most existing methods utilize counterfactual learning to debias recommender systems. Among them, the doubly robust (DR) estimator has achieved competitive performance by combining the error imputation based (EIB) estimator and the inverse propensity score (IPS) estimator in a doubly robust way. However, inaccurate error imputation may result in its higher variance than the IPS estimator. Worse still, existing methods typically use simple model-agnostic methods to estimate the imputation error, which are not sufficient to approximate the dynamically changing model-correlated target (i.e., the gradient direction of the prediction model). To solve these problems, we first derive the bias and variance of the DR estimator. Based on it, a more robust doubly robust (MRDR) estimator has been proposed to further reduce its variance while retaining its double robustness. Moreover, we propose a novel double learning approach for the MRDR estimator, which can convert the error imputation into the general CVR estimation. Besides, we empirically verify that the proposed learning scheme can further eliminate the high variance problem of the imputation learning. To evaluate its effectiveness, extensive experiments are conducted on a semi-synthetic dataset and two real-world datasets. The results demonstrate the superiority of the proposed approach over the state-of-the-art methods. The code is available at https://github.com/guosyjlu/MRDR-DL.

cs.LG↗

Self-paced Ensemble for Highly Imbalanced Massive Data Classification

Many real-world applications reveal difficulties in learning classifiers from imbalanced data. The rising big data era has been witnessing more classification tasks with large-scale but extremely imbalance and low-quality datasets. Most of existing learning methods suffer from poor performance or low computation efficiency under such a scenario. To tackle this problem, we conduct deep investigations into the nature of class imbalance, which reveals that not only the disproportion between classes, but also other difficulties embedded in the nature of data, especially, noises and class overlapping, prevent us from learning effective classifiers. Taking those factors into consideration, we propose a novel framework for imbalance classification that aims to generate a strong ensemble by self-paced harmonizing data hardness via under-sampling. Extensive experiments have shown that this new framework, while being very computationally efficient, can lead to robust performance even under highly overlapping classes and extremely skewed distribution. Note that, our methods can be easily adapted to most of existing learning methods (e.g., C4.5, SVM, GBDT and Neural Network) to boost their performance on imbalanced data.

cs.LG↗