Heinrich Brinck | Searcharxiv

arXiv2021

DUNEuro -- A software toolbox for forward modeling in bioelectromagnetism

Accurate and efficient source analysis in electro- and magnetoencephalography using sophisticated realistic head geometries requires advanced numerical approaches. This paper presents DUNEuro, a free and open source C++ software toolbox for forward modeling in bioelectromagnetism. Building upon the DUNE framework, it provides implementations of modern fitted and unfitted finite element methods to efficiently solve the forward problems in electro- and magnetoencephalography. The user can choose between a variety of different source models that are implemented. The software's aim is to provide interfaces that are extendible and easy-to-use. In order to enable a closer integration into existing analysis pipelines, interfaces to Python and Matlab are provided. The practical use is demonstrated by a source analysis example of somatosensory evoked potentials using a realistic six compartment head model.

cs.MS↗

arXiv2016

The Unfitted Discontinuous Galerkin Method for Solving the EEG Forward Problem

Objective: The purpose of this study is to introduce and evaluate the unfitted discontinuous Galerkin finite element method (UDG-FEM) for solving the electroencephalography (EEG) forward problem. Methods: This new approach for source analysis does not use a geometry conforming volume triangulation, but instead uses a structured mesh that does not resolve the geometry. The geometry is described using level set functions and is incorporated implicitly in its mathematical formulation. As no triangulation is necessary, the complexity of a simulation pipeline and the need for manual interaction for patient specific simulations can be reduced and is comparable with that of the FEM for hexahedral meshes. In addition, it maintains conservation laws on a discrete level. Here, we present the theory for UDG-FEM forward modeling, its verification using quasi-analytical solutions in multi-layer sphere models and an evaluation in a comparison with a discontinuous Galerkin (DG-FEM) method on hexahedral and on conforming tetrahedral meshes. We furthermore apply the UDG-FEM forward approach in a realistic head model simulation study. Results: The given results show convergence and indicate a good overall accuracy of the UDG-FEM approach. UDG-FEM performs comparable or even better than DG-FEM on a conforming tetrahedral mesh while providing a less complex simulation pipeline. When compared to DG-FEM on hexahedral meshes, an overall better accuracy is achieved. Conclusion: The UDG-FEM approach is an accurate, flexible and promising method to solve the EEG forward problem. Significance: This study shows the first application of the UDG-FEM approach to the EEG forward problem.

cs.CE↗