arXiv subjects

Hermann Scharfetter

Publications and source records attributed to Hermann Scharfetter.

4 recordsLinked to original sources

arXiv2026

FENCE: Flexible Electric Noise reduCtion Endo-shield for the Suppression of Electromagnetic Interference in Low-Field MRI

Electromagnetic interference (EMI) is a significant challenge for low-field MRI systems operating without conventional Faraday-shielded rooms. Traditional EMI mitigation approaches include external shields, subject grounding via electrodes, or active noise cancellation requiring synchronized receive channels. These methods either limit portability, introduce patient discomfort, or demand advanced hardware. In this work, we start from the hypothesis that EMI primarily couples capacitively from the body to the RF coil. We investigated two methods of blocking capacitive coupling while preserving inductive MRI signal detection: First, we employed capacitive segmentation of the RF coil and studied its effect on EMI coupling. Second, we present FENCE (Flexible Electromagnetic Noise reduCtion Endo-shield), a novel approach blocking capacitive coupling using flexible PCB shields placed inside the RF coil. FENCE can be retrofitted to existing RF coils. Finite element (FE) simulations were used to estimate the expected shielding performance and the impact on RF coil losses prior to practical implementation. Testing in various realistic scenarios then demonstrated that the combination of FENCE with segmented solenoid coils is effective against both environmental noise sources and controlled EMI. In phantom experiments, FENCE significantly improved imaging performance and reduced EMI levels to near-baseline levels with 9% reduction in coil quality factor (Q factor), showing good agreement with the predictions from the FE simulations. In-vivo head imaging confirmed these results across diverse electromagnetic environments significantly improving imaging performance while showing an ~18% decrease in Q factor. FENCE provides a simple method for EMI mitigation in low-field MRI, enhancing image quality while maintaining system portability and accessibility.

physics.med-ph↗

arXiv2021

Joint multi-field T$_1$ quantification for fast field-cycling MRI

Purpose: Recent developments in hardware design enable the use of Fast Field-Cycling (FFC) techniques in MRI to exploit the different relaxation rates at very low field strength, achieving novel contrast. The method opens new avenues for in vivo characterisations of pathologies but at the expense of longer acquisition times. To mitigate this we propose a model-based reconstruction method that fully exploits the high information redundancy offered by FFC methods. Methods: The proposed model-based approach utilizes joint spatial information from all fields by means of a Frobenius - total generalized variation regularization. The algorithm was tested on brain stroke images, both simulated and acquired from FFC patients scans using an FFC spin echo sequences. The results are compared to three non-linear least squares fits with progressively increasing complexity. Results: The proposed method shows excellent abilities to remove noise while maintaining sharp image features with large signal-to-noise ratio gains at low-field images, clearly outperforming the reference approach. Especially patient data shows huge improvements in visual appearance over all fields. Conclusion: The proposed reconstruction technique largely improves FFC image quality, further pushing this new technology towards clinical standards.

eess.SP↗

arXiv2018

R1 dispersion contrast at high field with fast field-cycling MRI

Contrast agents with a strong $R_1$ dispersion have been shown to be effective in generating target-specific contrast in MRI. The utilization of this $R_1$ field dependence requires the adaptation of a MRI scanner for fast field-cycling (FFC). Here, we present the first implementation and validation of FFC-MRI at a clinical field strength of 3 T. A field-cycling range of $\pm$100 mT around the nominal $B_0$ field was realized by inserting an additional insert coil into an otherwise conventional MRI system. System validation was successfully performed with selected iron oxide magnetic nanoparticles and comparison to FFC-NMR relaxometry measurements. Furthermore, we show proof-of-principle $R_1$ dispersion imaging and demonstrate the capability of generating R1 dispersion contrast at high field with suppressed background signal. With the presented ready-to-use hardware setup it is possible to investigate MRI contrast agents with a strong R1 dispersion at a field strength of 3 T.

physics.med-ph↗

arXiv2018

A cryostatic, fast scanning, wideband NQR spectrometer for the VHF range

In the search for a novel MRI contrast agent which relies on T1 shortening due to quadrupolar interaction between Bi nuclei and protons, a fast scanning wideband system for zero-field nuclear quadrupole resonance (NQR) spectroscopy is required. Established NQR probeheads with motor-driven tune-match stages are usually bulky and slow, which can be prohibitive if it comes to Bi compounds with low SNR (excessive averaging) and long quadrupolar T1 times. Moreover many experiments yield better results at low temperatures such as 77K (liquid nitrogen, LN) thus requiring easy to use cryo-probeheads. In this paper we present electronically tuned wideband probeheads for bands in the frequency range 20 - 120 MHz which can be immersed in LN and which enable very fast explorative scans over the whole range. To this end we apply an interleaved subspectrum sampling strategy (ISS) which relies on the electronic tuning capability. The superiority of the new concept is demonstrated with an experimental scan of triphenylbismuth from 24-116 MHz both at room temperature and in LN. Especially for the first transition which exhibits extremely long T1 times (64ms) and low signal the new approach allows an acceleration factor by more than 100 when compared to classical methods.

physics.med-ph↗