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Hong Zhang

Publications and source records attributed to Hong Zhang.

At least 163 records · Page 9Linked to original sources

CANAMRF: An Attention-Based Model for Multimodal Depression Detection

Multimodal depression detection is an important research topic that aims to predict human mental states using multimodal data. Previous methods treat different modalities equally and fuse each modality by naïve mathematical operations without measuring the relative importance between them, which cannot obtain well-performed multimodal representations for downstream depression tasks. In order to tackle the aforementioned concern, we present a Cross-modal Attention Network with Adaptive Multi-modal Recurrent Fusion (CANAMRF) for multimodal depression detection. CANAMRF is constructed by a multimodal feature extractor, an Adaptive Multimodal Recurrent Fusion module, and a Hybrid Attention Module. Through experimentation on two benchmark datasets, CANAMRF demonstrates state-of-the-art performance, underscoring the effectiveness of our proposed approach.

cs.CL↗

Study Duration Prediction for Clinical Trials with Time-to-Event Endpoints Using Mixture Distributions Accounting for Heterogeneous Population

In the era of precision medicine, more and more clinical trials are now driven or guided by biomarkers, which are patient characteristics objectively measured and evaluated as indicators of normal biological processes, pathogenic processes, or pharmacologic responses to therapeutic interventions. With the overarching objective to optimize and personalize disease management, biomarker-guided clinical trials increase the efficiency by appropriately utilizing prognostic or predictive biomarkers in the design. However, the efficiency gain is often not quantitatively compared to the traditional all-comers design, in which a faster enrollment rate is expected (e.g. due to no restriction to biomarker positive patients) potentially leading to a shorter duration. To accurately predict biomarker-guided trial duration, we propose a general framework using mixture distributions accounting for heterogeneous population. Extensive simulations are performed to evaluate the impact of heterogeneous population and the dynamics of biomarker characteristics and disease on the study duration. Several influential parameters including median survival time, enrollment rate, biomarker prevalence and effect size are identitied. Re-assessments of two publicly available trials are conducted to empirically validate the prediction accuracy and to demonstrate the practical utility. The R package \emph{detest} is developed to implement the proposed method and is publicly available on CRAN.

stat.ME↗

Memory-Efficient Reversible Spiking Neural Networks

Spiking neural networks (SNNs) are potential competitors to artificial neural networks (ANNs) due to their high energy-efficiency on neuromorphic hardware. However, SNNs are unfolded over simulation time steps during the training process. Thus, SNNs require much more memory than ANNs, which impedes the training of deeper SNN models. In this paper, we propose the reversible spiking neural network to reduce the memory cost of intermediate activations and membrane potentials during training. Firstly, we extend the reversible architecture along temporal dimension and propose the reversible spiking block, which can reconstruct the computational graph and recompute all intermediate variables in forward pass with a reverse process. On this basis, we adopt the state-of-the-art SNN models to the reversible variants, namely reversible spiking ResNet (RevSResNet) and reversible spiking transformer (RevSFormer). Through experiments on static and neuromorphic datasets, we demonstrate that the memory cost per image of our reversible SNNs does not increase with the network depth. On CIFAR10 and CIFAR100 datasets, our RevSResNet37 and RevSFormer-4-384 achieve comparable accuracies and consume 3.79x and 3.00x lower GPU memory per image than their counterparts with roughly identical model complexity and parameters. We believe that this work can unleash the memory constraints in SNN training and pave the way for training extremely large and deep SNNs. The code is available at https://github.com/mi804/RevSNN.git.

cs.CV↗

SPFNO: Spectral operator learning for PDEs with Dirichlet and Neumann boundary conditions

Neural operators have been validated as promising deep surrogate models for solving partial differential equations (PDEs). Despite the critical role of boundary conditions in PDEs, however, only a limited number of neural operators robustly enforce these conditions. In this paper we introduce semi-periodic Fourier neural operator (SPFNO), a novel spectral operator learning method, to learn the target operators of PDEs with non-periodic BCs. This method extends our previous work (arXiv:2206.12698), which showed significant improvements by employing enhanced neural operators that precisely satisfy the boundary conditions. However, the previous work is associated with Gaussian grids, restricting comprehensive comparisons across most public datasets. Additionally, we present numerical results for various PDEs such as the viscous Burgers' equation, Darcy flow, incompressible pipe flow, and coupled reactiondiffusion equations. These results demonstrate the computational efficiency, resolution invariant property, and BC-satisfaction behavior of proposed model. An accuracy improvement of approximately 1.7X-4.7X over the non-BC-satisfying baselines is also achieved. Furthermore, our studies on SOL underscore the significance of satisfying BCs as a criterion for deep surrogate models of PDEs.

math.NA↗

From Kubernetes to Knactor: A Data-Centric Rethink of Service Composition

Microservices are increasingly used in modern applications, leading to a growing need for effective service composition solutions. However, we argue that traditional API-centric composition mechanisms (e.g., RPC, REST, and Pub/Sub) hamper the modularity of microservices. These mechanisms introduce rigid code-level coupling, scatter composition logic, and hinder visibility into cross-service data exchanges. Ultimately, these limitations complicate the maintenance and evolution of microservice-based applications. In response, we propose a rethinking of service composition and present Knactor, a new data-centric composition framework to restore the modularity that microservices were intended to offer. Knactor decouples service composition from service development, allowing composition to be implemented as explicit data exchanges among multiple services. Our initial case study suggests that Knactor simplifies service composition and creates new opportunities for optimizations.

cs.DC↗

A Convolutional-Transformer Network for Crack Segmentation with Boundary Awareness

Cracks play a crucial role in assessing the safety and durability of manufactured buildings. However, the long and sharp topological features and complex background of cracks make the task of crack segmentation extremely challenging. In this paper, we propose a novel convolutional-transformer network based on encoder-decoder architecture to solve this challenge. Particularly, we designed a Dilated Residual Block (DRB) and a Boundary Awareness Module (BAM). The DRB pays attention to the local detail of cracks and adjusts the feature dimension for other blocks as needed. And the BAM learns the boundary features from the dilated crack label. Furthermore, the DRB is combined with a lightweight transformer that captures global information to serve as an effective encoder. Experimental results show that the proposed network performs better than state-of-the-art algorithms on two typical datasets. Datasets, code, and trained models are available for research at https://github.com/HqiTao/CT-crackseg.

cs.CV↗

L-MAE: Masked Autoencoders are Semantic Segmentation Datasets Augmenter

Generating semantic segmentation datasets has consistently been laborious and time-consuming, particularly in the context of large models or specialized domains(i.e. Medical Imaging or Remote Sensing). Specifically, large models necessitate a substantial volume of data, while datasets in professional domains frequently require the involvement of domain experts. Both scenarios are susceptible to inaccurate data labeling, which can significantly affect the ultimate performance of the trained model. This paper proposes a simple and effective label pixel-level completion method, \textbf{Label Mask AutoEncoder} (L-MAE), which fully uses the existing information in the label to generate the complete label. The proposed model are the first to apply the Mask Auto-Encoder to downstream tasks. In detail, L-MAE adopts the fusion strategy that stacks the label and the corresponding image, namely fuse map. Moreover, since some of the image information is lost when masking the fuse map, direct reconstruction may lead to poor performance. We proposed Image Patch Supplement algorithm to supplement the missing information during the mask-reconstruct process, and empirically found that an average of 4.1\% mIoU can be improved. We conducted a experiment to evaluate the efficacy of L-MAE to complete the dataset. We employed a degraded Pascal VOC dataset and the degraded dataset enhanced by L-MAE to train an identical conventional semantic segmentation model for the initial set of experiments. The results of these experiments demonstrate a performance enhancement of 13.5\% in the model trained with the L-MAE-enhanced dataset compared to the unenhanced dataset.

cs.CV↗

RTrack: Accelerating Convergence for Visual Object Tracking via Pseudo-Boxes Exploration

Single object tracking (SOT) heavily relies on the representation of the target object as a bounding box. However, due to the potential deformation and rotation experienced by the tracked targets, the genuine bounding box fails to capture the appearance information explicitly and introduces cluttered background. This paper proposes RTrack, a novel object representation baseline tracker that utilizes a set of sample points to get a pseudo bounding box. RTrack automatically arranges these points to define the spatial extents and highlight local areas. Building upon the baseline, we conducted an in-depth exploration of the training potential and introduced a one-to-many leading assignment strategy. It is worth noting that our approach achieves competitive performance to the state-of-the-art trackers on the GOT-10k dataset while reducing training time to just 10% of the previous state-of-the-art (SOTA) trackers' training costs. The substantial reduction in training costs brings single-object tracking (SOT) closer to the object detection (OD) task. Extensive experiments demonstrate that our proposed RTrack achieves SOTA results with faster convergence.

cs.CV↗

Causal inference with outcome dependent sampling and mismeasured outcome

Outcome-dependent sampling designs are extensively utilized in various scientific disciplines, including epidemiology, ecology, and economics, with retrospective case-control studies being specific examples of such designs. Additionally, if the outcome used for sample selection is also mismeasured, then it is even more challenging to estimate the average treatment effect (ATE) accurately. To our knowledge, no existing method can address these two issues simultaneously. In this paper, we establish the identifiability of ATE and propose a novel method for estimating ATE in the context of generalized linear model. The estimator is shown to be consistent under some regularity conditions. To relax the model assumption, we also consider generalized additive model. We propose to estimate ATE using penalized B-splines and establish asymptotic properties for the proposed estimator. Our methods are evaluated through extensive simulation studies and the application to a dataset from the UK Biobank, with alcohol intake as the treatment and gout as the outcome.

stat.ME↗

On Fast Simulation of Dynamical System with Neural Vector Enhanced Numerical Solver

The large-scale simulation of dynamical systems is critical in numerous scientific and engineering disciplines. However, traditional numerical solvers are limited by the choice of step sizes when estimating integration, resulting in a trade-off between accuracy and computational efficiency. To address this challenge, we introduce a deep learning-based corrector called Neural Vector (NeurVec), which can compensate for integration errors and enable larger time step sizes in simulations. Our extensive experiments on a variety of complex dynamical system benchmarks demonstrate that NeurVec exhibits remarkable generalization capability on a continuous phase space, even when trained using limited and discrete data. NeurVec significantly accelerates traditional solvers, achieving speeds tens to hundreds of times faster while maintaining high levels of accuracy and stability. Moreover, NeurVec's simple-yet-effective design, combined with its ease of implementation, has the potential to establish a new paradigm for fast-solving differential equations based on deep learning.

cs.CE↗

GraspGPT: Leveraging Semantic Knowledge from a Large Language Model for Task-Oriented Grasping

Task-oriented grasping (TOG) refers to the problem of predicting grasps on an object that enable subsequent manipulation tasks. To model the complex relationships between objects, tasks, and grasps, existing methods incorporate semantic knowledge as priors into TOG pipelines. However, the existing semantic knowledge is typically constructed based on closed-world concept sets, restraining the generalization to novel concepts out of the pre-defined sets. To address this issue, we propose GraspGPT, a large language model (LLM) based TOG framework that leverages the open-end semantic knowledge from an LLM to achieve zero-shot generalization to novel concepts. We conduct experiments on Language Augmented TaskGrasp (LA-TaskGrasp) dataset and demonstrate that GraspGPT outperforms existing TOG methods on different held-out settings when generalizing to novel concepts out of the training set. The effectiveness of GraspGPT is further validated in real-robot experiments. Our code, data, appendix, and video are publicly available at https://sites.google.com/view/graspgpt/.

cs.RO↗

Efficient Object Rearrangement via Multi-view Fusion

The prospect of assistive robots aiding in object organization has always been compelling. In an image-goal setting, the robot rearranges the current scene to match the single image captured from the goal scene. The key to an image-goal rearrangement system is estimating the desired placement pose of each object based on the single goal image and observations from the current scene. In order to establish sufficient associations for accurate estimation, the system should observe an object from a viewpoint similar to that in the goal image. Existing image-goal rearrangement systems, due to their reliance on a fixed viewpoint for perception, often require redundant manipulations to randomly adjust an object's pose for a better perspective. Addressing this inefficiency, we introduce a novel object rearrangement system that employs multi-view fusion. By observing the current scene from multiple viewpoints before manipulating objects, our approach can estimate a more accurate pose without redundant manipulation times. A standard visual localization pipeline at the object level is developed to capitalize on the advantages of multi-view observations. Simulation results demonstrate that the efficiency of our system outperforms existing single-view systems. The effectiveness of our system is further validated in a physical experiment.

cs.RO↗

DSRRTracker: Dynamic Search Region Refinement for Attention-based Siamese Multi-Object Tracking

Many multi-object tracking (MOT) methods follow the framework of "tracking by detection", which associates the target objects-of-interest based on the detection results. However, due to the separate models for detection and association, the tracking results are not optimal.Moreover, the speed is limited by some cumbersome association methods to achieve high tracking performance. In this work, we propose an end-to-end MOT method, with a Gaussian filter-inspired dynamic search region refinement module to dynamically filter and refine the search region by considering both the template information from the past frames and the detection results from the current frame with little computational burden, and a lightweight attention-based tracking head to achieve the effective fine-grained instance association. Extensive experiments and ablation study on MOT17 and MOT20 datasets demonstrate that our method can achieve the state-of-the-art performance with reasonable speed.

cs.CV↗

Recovering a Molecule's 3D Dynamics from Liquid-phase Electron Microscopy Movies

The dynamics of biomolecules are crucial for our understanding of their functioning in living systems. However, current 3D imaging techniques, such as cryogenic electron microscopy (cryo-EM), require freezing the sample, which limits the observation of their conformational changes in real time. The innovative liquid-phase electron microscopy (liquid-phase EM) technique allows molecules to be placed in the native liquid environment, providing a unique opportunity to observe their dynamics. In this paper, we propose TEMPOR, a Temporal Electron MicroscoPy Object Reconstruction algorithm for liquid-phase EM that leverages an implicit neural representation (INR) and a dynamical variational auto-encoder (DVAE) to recover time series of molecular structures. We demonstrate its advantages in recovering different motion dynamics from two simulated datasets, 7bcq and Cas9. To our knowledge, our work is the first attempt to directly recover 3D structures of a temporally-varying particle from liquid-phase EM movies. It provides a promising new approach for studying molecules' 3D dynamics in structural biology.

q-bio.QM↗

Next-to-leading-order solution to Kerr-Newman black hole superradiance

The superradiant instabilities of Kerr-Newman black holes with charged or uncharged massive spin-0 fields are calculated analytically to the next-to-leading order in the limit of $α\sim r_g μ\ll 1$. A missing factor of $1/2$ in the previous leading-order result is identified. The next-to-leading order result has a compact form and is in good agreement with existing numerical calculations. The percentage error increases with $α$, from a few percent for $α\sim 0.1$ to about $50\%$ for $α\sim 0.4$. Massive neutral scalars too heavy to be produced with Kerr black hole superradiance may exist in the superradiant region of Kerr-Newman black holes.

gr-qc↗

A memory-efficient neural ODE framework based on high-level adjoint differentiation

Neural ordinary differential equations (neural ODEs) have emerged as a novel network architecture that bridges dynamical systems and deep learning. However, the gradient obtained with the continuous adjoint method in the vanilla neural ODE is not reverse-accurate. Other approaches suffer either from an excessive memory requirement due to deep computational graphs or from limited choices for the time integration scheme, hampering their application to large-scale complex dynamical systems. To achieve accurate gradients without compromising memory efficiency and flexibility, we present a new neural ODE framework, PNODE, based on high-level discrete adjoint algorithmic differentiation. By leveraging discrete adjoint time integrators and advanced checkpointing strategies tailored for these integrators, PNODE can provide a balance between memory and computational costs, while computing the gradients consistently and accurately. We provide an open-source implementation based on PyTorch and PETSc, one of the most commonly used portable, scalable scientific computing libraries. We demonstrate the performance through extensive numerical experiments on image classification and continuous normalizing flow problems. We show that PNODE achieves the highest memory efficiency when compared with other reverse-accurate methods. On the image classification problems, PNODE is up to two times faster than the vanilla neural ODE and up to 2.3 times faster than the best existing reverse-accurate method. We also show that PNODE enables the use of the implicit time integration methods that are needed for stiff dynamical systems.

cs.LG↗

Adjusting for non-confounding covariates in case-control association studies

There is a considerable literature in case-control logistic regression on whether or not non-confounding covariates should be adjusted for. However, only limited and ad hoc theoretical results are available on this important topic. A constrained maximum likelihood method was recently proposed, which appears to be generally more powerful than logistic regression methods with or without adjusting for non-confounding covariates. This note provides a theoretical clarification for the case-control logistic regression with and without covariate adjustment and the constrained maximum likelihood method on their relative performances in terms of asymptotic relative efficiencies. We show that the benefit of covariate adjustment in the case-control logistic regression depends on the disease prevalence. We also show that the constrained maximum likelihood estimator gives an asymptotically uniformly most powerful test.

math.ST↗

DPSeq: A Novel and Efficient Digital Pathology Classifier for Predicting Cancer Biomarkers using Sequencer Architecture

In digital pathology tasks, transformers have achieved state-of-the-art results, surpassing convolutional neural networks (CNNs). However, transformers are usually complex and resource intensive. In this study, we developed a novel and efficient digital pathology classifier called DPSeq, to predict cancer biomarkers through fine-tuning a sequencer architecture integrating horizon and vertical bidirectional long short-term memory (BiLSTM) networks. Using hematoxylin and eosin (H&E)-stained histopathological images of colorectal cancer (CRC) from two international datasets: The Cancer Genome Atlas (TCGA) and Molecular and Cellular Oncology (MCO), the predictive performance of DPSeq was evaluated in series of experiments. DPSeq demonstrated exceptional performance for predicting key biomarkers in CRC (MSI status, Hypermutation, CIMP status, BRAF mutation, TP53 mutation and chromosomal instability [CING]), outperforming most published state-of-the-art classifiers in a within-cohort internal validation and a cross-cohort external validation. Additionally, under the same experimental conditions using the same set of training and testing datasets, DPSeq surpassed 4 CNN (ResNet18, ResNet50, MobileNetV2, and EfficientNet) and 2 transformer (ViT and Swin-T) models, achieving the highest AUROC and AUPRC values in predicting MSI status, BRAF mutation, and CIMP status. Furthermore, DPSeq required less time for both training and prediction due to its simple architecture. Therefore, DPSeq appears to be the preferred choice over transformer and CNN models for predicting cancer biomarkers.

eess.IV↗