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Hongyu An

Publications and source records attributed to Hongyu An.

At least 19 recordsLinked to original sources

Neuromorphic Silicon Neuron Controller for Adaptive Deep Brain Stimulation in Parkinson's Disease

Parkinson's disease (PD) affects millions worldwide and causes severe motor symptoms. Adaptive deep brain stimulation (aDBS) delivers physiologically informed stimulation that can track fluctuations in PD motor symptoms, enabling more intelligent DBS control. However, most existing aDBS approaches are primarily algorithm- and software-driven, with limited efforts toward circuit realization, particularly low-power and implantable integrated circuits. This paper presents the Silicon Leaky Integrate-and-Fire Deep Brain Stimulation (SiLIF-DBS) controller, a neuromorphic silicon neuron stimulator implemented with metal-oxide-semiconductor (CMOS) technology. For system-level evaluation, a simplified computational model of the SiLIF-DBS controller is derived and embedded within a Parkinsonian cortico-basal ganglia framework for closed-loop validation. The system is driven by beta-band subthalamic nucleus local field potentials (STN-LFPs), with their average rectified value (Beta ARV) used as the control biomarker. Our SiLIF-DBS controller for aDBS suppresses pathological beta activity while consuming only 25% of the power required by open-loop stimulation and achieving a suppression efficiency of $5.85\%$/$\mu$W. Overall, our SiLIF-DBS controller achieves strong beta suppression at substantially reduced power, delivering high suppression efficiency that demonstrates it is a viable foundation for low-power implantable aDBS.

cs.AR

D$^{2}$R$^{2}$OSR: Degradation-Disentangled Representation for Real-World Omnidirectional Image Super-Resolution

With the growing demand for immersive visual experiences, high-quality omnidirectional images (ODIs) have become increasingly important. However, limitations in imaging devices and transmission bandwidth often lead to low-resolution ODIs, hindering the rendering of fine-grained 360{\deg} details, especially in the presence of real-world degradations and geometric distortions. Existing real-world super-resolution (Real-SR) methods are inadequate for ODIs, as their degradation models fail to account for the complex imaging pipeline involving fisheye capture and Equirectangular Projection (ERP), introducing severe aliasing and projection-specific distortions. To address these challenges, we propose D$^{2}$R$^{2}$OSR, a Degradation-Disentangled Representation framework for Real-world Omnidirectional image Super-Resolution. D$^{2}$R$^{2}$OSR explicitly models degradations arising from both fisheye imaging and ERP projection, guided by two key insights: (1) projection priors play a critical role in shaping real-world degradations, and (2) human perception in immersive environments is inherently viewpoint-centric. Accordingly, we introduce a Perspective Projection Representation (PPR) operating alongside the ERP branch to capture viewpoint-aware features, together with a Degradation-Specific Module (DSM) that jointly models ERP-induced geometric distortions and PPR-specific real-world degradations. Extensive experiments demonstrate that D$^{2}$R$^{2}$OSR achieves state-of-the-art performance and produces visually compelling, high-fidelity omnidirectional Real-SR results while maintaining favorable computational efficiency for low-resource deployment.

cs.CV

Unanticipated Adversarial Robustness of Semantic Communication

Semantic communication, enabled by deep joint source-channel coding (DeepJSCC), is widely expected to inherit the vulnerability of deep learning to adversarial perturbations. This paper challenges this prevailing belief and reveals a counterintuitive finding: semantic communication systems exhibit unanticipated adversarial robustness that can exceed that of classical separate source-channel coding systems. On the theoretical front, we establish fundamental bounds on the minimum attack power required to induce a target distortion, overcoming the analytical intractability of highly nonlinear DeepJSCC models by leveraging Lipschitz smoothness. We prove that the implicit regularization from noisy training forces decoder smoothness, a property that inherently provides built-in protection against adversarial attacks. To enable rigorous and fair comparison, we develop two novel attack methodologies that address previously unexplored vulnerabilities: a structure-aware vulnerable set attack that, for the first time, exploits graph-theoretic vulnerabilities in LDPC codes to induce decoding failure with minimal energy, and a progressive gradient ascent attack that leverages the differentiability of DeepJSCC to efficiently find minimum-power perturbations. Designing such attacks is challenging, as classical systems lack gradient information while semantic systems require navigating high-dimensional, non-convex spaces; our methods fill these critical gaps in the literature. Extensive experiments demonstrate that semantic communication requires up to $14$-$16\times$ more attack power to achieve the same distortion as classical systems, empirically substantiating its superior robustness.

cs.IT

Position: Evaluation of Visual Processing Should Be Human-Centered, Not Metric-Centered

This position paper argues that the evaluation of modern visual processing systems should no longer be driven primarily by single-metric image quality assessment benchmarks, particularly in the era of generative and perception-oriented methods. Image restoration exemplifies this divergence: while objective IQA metrics enable reproducible, scalable evaluation, they have increasingly drifted apart from human perception and user preferences. We contend that this mismatch risks constraining innovation and misguiding research progress across visual processing tasks. Rather than rejecting metrics altogether, this paper calls for a rebalancing of evaluation paradigms, advocating a more human-centered, context-aware, and fine-grained approach to assessing the visual models' outcomes.

cs.CV

A Unified Framework for Multimodal Image Reconstruction and Synthesis using Denoising Diffusion Models

Image reconstruction and image synthesis are important for handling incomplete multimodal imaging data, but existing methods require various task-specific models, complicating training and deployment workflows. We introduce Any2all, a unified framework that addresses this limitation by formulating these disparate tasks as a single virtual inpainting problem. We train a single, unconditional diffusion model on the complete multimodal data stack. This model is then adapted at inference time to ``inpaint'' all target modalities from any combination of inputs of available clean images or noisy measurements. We validated Any2all on a PET/MR/CT brain dataset. Our results show that Any2all can achieve excellent performance on both multimodal reconstruction and synthesis tasks, consistently yielding images with competitive distortion-based performance and superior perceptual quality over specialized methods.

eess.IV

A Respiratory Motion Analysis for Guiding Stereotactic Arrhythmia Radiotherapy Motion Management

Stereotactic Arrhythmia Radiotherapy (STAR) treats ventricular tachycardia (VT) but requires internal target volume (ITV) expansions to compensate for cardiorespiratory motion. Current clinical r4DCT imaging methods are limited, and the reconstructed r4DCTs suffer from unmanaged cardiac motion artifacts that affect the quantitative assessment of respiratory motion. A groupwise surface-to-surface deformable image registration (DIR) algorithm, named gCGF, was developed. A novel principal component filtering (PCF) mechanism and a spatial smoothing mechanism were developed and incorporated into gCGF to iteratively register heart contours from an average respiratory-phase CT to ten r4DCT phases while removing random cardiac motion from the cyclic respiratory motion. The performance of the groupwise DIR was quantitatively validated using 8 digital phantoms with simulated cardiac artifacts. An ablation study was conducted to compare gCGF to another comparable state-of-the-art groupwise DIR method. gCGF was applied to r4DCTs of 20 STAR patients to analyze the respiratory motion of the heart. Validation on digital phantoms showed that gCGF achieved a mean target registration error of 0.63+-0.51 mm while successfully achieving phase smoothness and reducing cardiac motion artifacts. Among all STAR patients, the heart's maximum and mean respiratory motion magnitudes ranged from 3.6 to 7.9 mm and 1.0 mm to 2.6 mm. The peak-to-peak motion range was from 6.2 to 14.7 mm. For VT targets, the max and mean motion magnitude ranges were 3.0 to 6.7 mm and 0.8 to 2.9 mm, respectively. The peak-to-peak range was from 4.7 to 11.8 mm. Significant dominance of the first principal component of the motion direction was observed (p = 0).

physics.med-ph

SANR: Scene-Aware Neural Representation for Light Field Image Compression with Rate-Distortion Optimization

Light field images capture multi-view scene information and play a crucial role in 3D scene reconstruction. However, their high-dimensional nature results in enormous data volumes, posing a significant challenge for efficient compression in practical storage and transmission scenarios. Although neural representation-based methods have shown promise in light field image compression, most approaches rely on direct coordinate-to-pixel mapping through implicit neural representation (INR), often neglecting the explicit modeling of scene structure. Moreover, they typically lack end-to-end rate-distortion optimization, limiting their compression efficiency. To address these limitations, we propose SANR, a Scene-Aware Neural Representation framework for light field image compression with end-to-end rate-distortion optimization. For scene awareness, SANR introduces a hierarchical scene modeling block that leverages multi-scale latent codes to capture intrinsic scene structures, thereby reducing the information gap between INR input coordinates and the target light field image. From a compression perspective, SANR is the first to incorporate entropy-constrained quantization-aware training (QAT) into neural representation-based light field image compression, enabling end-to-end rate-distortion optimization. Extensive experiment results demonstrate that SANR significantly outperforms state-of-the-art techniques regarding rate-distortion performance with a 65.62\% BD-rate saving against HEVC.

eess.IV

Measurement Score-Based MRI Reconstruction with Automatic Coil Sensitivity Estimation

Diffusion-based inverse problem solvers (DIS) have recently shown outstanding performance in compressed-sensing parallel MRI reconstruction by combining diffusion priors with physical measurement models. However, they typically rely on pre-calibrated coil sensitivity maps (CSMs) and ground truth images, making them often impractical: CSMs are difficult to estimate accurately under heavy undersampling and ground-truth images are often unavailable. We propose Calibration-free Measurement Score-based diffusion Model (C-MSM), a new method that eliminates these dependencies by jointly performing automatic CSM estimation and self-supervised learning of measurement scores directly from k-space data. C-MSM reconstructs images by approximating the full posterior distribution through stochastic sampling over partial measurement posterior scores, while simultaneously estimating CSMs. Experiments on the multi-coil brain fastMRI dataset show that C-MSM achieves reconstruction performance close to DIS with clean diffusion priors -- even without access to clean training data and pre-calibrated CSMs.

eess.IV

Mimicking associative learning of rats via a neuromorphic robot in open field maze using spatial cell models

Data-driven Artificial Intelligence (AI) approaches have exhibited remarkable prowess across various cognitive tasks using extensive training data. However, the reliance on large datasets and neural networks presents challenges such as highpower consumption and limited adaptability, particularly in SWaP-constrained applications like planetary exploration. To address these issues, we propose enhancing the autonomous capabilities of intelligent robots by emulating the associative learning observed in animals. Associative learning enables animals to adapt to their environment by memorizing concurrent events. By replicating this mechanism, neuromorphic robots can navigate dynamic environments autonomously, learning from interactions to optimize performance. This paper explores the emulation of associative learning in rodents using neuromorphic robots within open-field maze environments, leveraging insights from spatial cells such as place and grid cells. By integrating these models, we aim to enable online associative learning for spatial tasks in real-time scenarios, bridging the gap between biological spatial cognition and robotics for advancements in autonomous systems.

cs.RO

Development and in silico imaging trial evaluation of a deep-learning-based transmission-less attenuation compensation method for DaT SPECT

Quantitative measures of dopamine transporter (DaT) uptake in caudate, putamen, and globus pallidus derived from DaT-single-photon emission computed tomography (SPECT) images are being investigated as biomarkers to diagnose, assess disease status, and track the progression of Parkinsonism. Reliable quantification from DaT-SPECT images requires performing attenuation compensation (AC), typically with a separate X-ray CT scan. Such CT-based AC (CTAC) has multiple challenges, a key one being the non-availability of X-ray CT component on many clinical SPECT systems. Even when a CT is available, the additional CT scan leads to increased radiation dose, costs, and complexity, potential quantification errors due to SPECT-CT misalignment, and higher training and regulatory requirements. To overcome the challenges with the requirement of a CT scan for AC in DaT SPECT, we propose a deep learning (DL)-based transmission-less AC method for DaT-SPECT (DaT-CTLESS). An in silico imaging trial, titled ISIT-DaT, was designed to evaluate the performance of DaT-CTLESS on the regional uptake quantification task. We observed that DaT-CTLESS yielded a significantly higher correlation with CTAC than that between UAC and CTAC on the regional DaT uptake quantification task. Further, DaT-CLTESS had an excellent agreement with CTAC on this task, significantly outperformed UAC in distinguishing patients with normal versus reduced putamen SBR, yielded good generalizability across two scanners, was generally insensitive to intra-regional uptake heterogeneity, demonstrated good repeatability, exhibited robust performance even as the size of the training data was reduced, and generally outperformed the other considered DL methods on the task of quantifying regional uptake across different training dataset sizes. These results provide a strong motivation for further clinical evaluation of DaT-CTLESS.

physics.med-ph

Measurement Score-Based Diffusion Model

Diffusion models are widely used in applications ranging from image generation to inverse problems. However, training diffusion models typically requires clean ground-truth images, which are unavailable in many applications. We introduce the Measurement Score-based diffusion Model (MSM), a novel framework that learns partial measurement scores using only noisy and subsampled measurements. MSM models the distribution of full measurements as an expectation over partial scores induced by randomized subsampling. To make the MSM representation computationally efficient, we also develop a stochastic sampling algorithm that generates full images by using a randomly selected subset of partial scores at each step. We additionally propose a new posterior sampling method for solving inverse problems that reconstructs images using these partial scores. We provide a theoretical analysis that bounds the Kullback-Leibler divergence between the distributions induced by full and stochastic sampling, establishing the accuracy of the proposed algorithm. We demonstrate the effectiveness of MSM on natural images and multi-coil MRI, showing that it can generate high-quality images and solve inverse problems -- all without access to clean training data. Code is available at https://github.com/wustl-cig/MSM.

eess.IV

The Tenth NTIRE 2025 Efficient Super-Resolution Challenge Report

This paper presents a comprehensive review of the NTIRE 2025 Challenge on Single-Image Efficient Super-Resolution (ESR). The challenge aimed to advance the development of deep models that optimize key computational metrics, i.e., runtime, parameters, and FLOPs, while achieving a PSNR of at least 26.90 dB on the $\operatorname{DIV2K\_LSDIR\_valid}$ dataset and 26.99 dB on the $\operatorname{DIV2K\_LSDIR\_test}$ dataset. A robust participation saw \textbf{244} registered entrants, with \textbf{43} teams submitting valid entries. This report meticulously analyzes these methods and results, emphasizing groundbreaking advancements in state-of-the-art single-image ESR techniques. The analysis highlights innovative approaches and establishes benchmarks for future research in the field.

cs.CV

Spatial Degradation-Aware and Temporal Consistent Diffusion Model for Compressed Video Super-Resolution

Due to storage and bandwidth limitations, videos transmitted over the Internet often exhibit low quality, characterized by low-resolution and compression artifacts. Although video super-resolution (VSR) is an efficient video enhancing technique, existing VSR methods focus less on compressed videos. Consequently, directly applying general VSR approaches fails to improve practical videos with compression artifacts, especially when frames are highly compressed at a low bit rate. The inevitable quantization information loss complicates the reconstruction of texture details. Recently, diffusion models have shown superior performance in low-level visual tasks. Leveraging the high-realism generation capability of diffusion models, we propose a novel method that exploits the priors of pre-trained diffusion models for compressed VSR. To mitigate spatial distortions and refine temporal consistency, we introduce a Spatial Degradation-Aware and Temporal Consistent (SDATC) diffusion model. Specifically, we incorporate a distortion control module (DCM) to modulate diffusion model inputs, thereby minimizing the impact of noise from low-quality frames on the generation stage. Subsequently, the diffusion model performs a denoising process to generate details, guided by a fine-tuned compression-aware prompt module (CAPM) and a spatio-temporal attention module (STAM). CAPM dynamically encodes compression-related information into prompts, enabling the sampling process to adapt to different degradation levels. Meanwhile, STAM extends the spatial attention mechanism into the spatio-temporal dimension, effectively capturing temporal correlations. Additionally, we utilize optical flow-based alignment during each denoising step to enhance the smoothness of output videos. Extensive experimental results on benchmark datasets demonstrate the effectiveness of our proposed modules in restoring compressed videos.

cs.CV

A Self-supervised Diffusion Bridge for MRI Reconstruction

Diffusion bridges (DBs) are a class of diffusion models that enable faster sampling by interpolating between two paired image distributions. Training traditional DBs for image reconstruction requires high-quality reference images, which limits their applicability to settings where such references are unavailable. We propose SelfDB as a novel self-supervised method for training DBs directly on available noisy measurements without any high-quality reference images. SelfDB formulates the diffusion process by further sub-sampling the available measurements two additional times and training a neural network to reverse the corresponding degradation process by using the available measurements as the training targets. We validate SelfDB on compressed sensing MRI, showing its superior performance compared to the denoising diffusion models.

eess.IV

A Generalizable 3D Diffusion Framework for Low-Dose and Few-View Cardiac SPECT

Myocardial perfusion imaging using SPECT is widely utilized to diagnose coronary artery diseases, but image quality can be negatively affected in low-dose and few-view acquisition settings. Although various deep learning methods have been introduced to improve image quality from low-dose or few-view SPECT data, previous approaches often fail to generalize across different acquisition settings, limiting their applicability in reality. This work introduced DiffSPECT-3D, a diffusion framework for 3D cardiac SPECT imaging that effectively adapts to different acquisition settings without requiring further network re-training or fine-tuning. Using both image and projection data, a consistency strategy is proposed to ensure that diffusion sampling at each step aligns with the low-dose/few-view projection measurements, the image data, and the scanner geometry, thus enabling generalization to different low-dose/few-view settings. Incorporating anatomical spatial information from CT and total variation constraint, we proposed a 2.5D conditional strategy to allow the DiffSPECT-3D to observe 3D contextual information from the entire image volume, addressing the 3D memory issues in diffusion model. We extensively evaluated the proposed method on 1,325 clinical 99mTc tetrofosmin stress/rest studies from 795 patients. Each study was reconstructed into 5 different low-count and 5 different few-view levels for model evaluations, ranging from 1% to 50% and from 1 view to 9 view, respectively. Validated against cardiac catheterization results and diagnostic comments from nuclear cardiologists, the presented results show the potential to achieve low-dose and few-view SPECT imaging without compromising clinical performance. Additionally, DiffSPECT-3D could be directly applied to full-dose SPECT images to further improve image quality, especially in a low-dose stress-first cardiac SPECT imaging protocol.

eess.IV

Ultrahigh-temperature ferromagnetism in ultrathin insulating films with ripple-infinite-layer structure

Ferromagnetism and electrical insulation are often at odds, signifying an inherent trade off. The simultaneous optimization of both in one material, essential for advancing spintronics and topological electronics, necessitates the individual manipulation over various degrees of freedom of strongly correlated electrons. Here, by selective control of the spin exchange and Coulomb interactions, we report the achievement of SrFeO2 thin films with resistivity above 106 Ohm.cm and strong magnetization with Curie temperature extrapolated to be 1200 K. Robust ferromagnetism is obtained down to 1.0 nm thickness on substrate and 2.0 nm for freestanding films. Featuring an out of plane oriented ripple infinite layer structure, this ferromagnetic insulating phase is obtained through extensive reduction of as grown brownmillerite SrFeO2.5 films at high compressive strains. Pronounced spin Hall magnetoresistance signals up to 0.0026 is further demonstrated with a Pt Hall bar device. Our findings promise emerging spintronic and topological electronic functionalities harnessing spin dynamics with minimized power dissipations.

cond-mat.mtrl-sci

Spatio-Temporal Distortion Aware Omnidirectional Video Super-Resolution

Omnidirectional videos (ODVs) provide an immersive visual experience by capturing the 360{\deg} scene. With the rapid advancements in virtual/augmented reality, metaverse, and generative artificial intelligence, the demand for high-quality ODVs is surging. However, ODVs often suffer from low resolution due to their wide field of view and limitations in capturing devices and transmission bandwidth. Although video super-resolution (SR) is a capable video quality enhancement technique, the performance ceiling and practical generalization of existing methods are limited when applied to ODVs due to their unique attributes. To alleviate spatial projection distortions and temporal flickering of ODVs, we propose a Spatio-Temporal Distortion Aware Network (STDAN) with joint spatio-temporal alignment and reconstruction. Specifically, we incorporate a spatio-temporal continuous alignment (STCA) to mitigate discrete geometric artifacts in parallel with temporal alignment. Subsequently, we introduce an interlaced multi-frame reconstruction (IMFR) to enhance temporal consistency. Furthermore, we employ latitude-saliency adaptive (LSA) weights to focus on regions with higher texture complexity and human-watching interest. By exploring a spatio-temporal jointly framework and real-world viewing strategies, STDAN effectively reinforces spatio-temporal coherence on a novel ODV-SR dataset and ensures affordable computational costs. Extensive experimental results demonstrate that STDAN outperforms state-of-the-art methods in improving visual fidelity and dynamic smoothness of ODVs.

cs.CV

Small metal artifact detection and inpainting in cardiac CT images

Background: Quantification of cardiac motion on pre-treatment CT imaging for stereotactic arrhythmia radiotherapy patients is difficult due to the presence of image artifacts caused by metal leads of implantable cardioverter-defibrillators (ICDs). New methods are needed to accurately reduce the metal artifacts in already reconstructed CTs to recover the otherwise lost anatomical information. Purpose: To develop a methodology to automatically detect metal artifacts in cardiac CT scans and inpaint the affected volume with anatomically consistent structures and values. Methods: ECG-gated 4DCT scans of 12 patients who underwent cardiac radiation therapy for treating ventricular tachycardia were collected. The metal artifacts in the images were manually contoured. A 2D U-Net deep learning (DL) model was developed to segment the metal artifacts. A dataset of synthetic CTs was prepared by adding metal artifacts from the patient images to artifact-free CTs. A 3D image inpainting DL model was trained to refill the metal artifact portion in the synthetic images with realistic values. The inpainting model was evaluated by analyzing the automated segmentation results of the four heart chambers on the synthetic dataset. Additionally, the raw cardiac patient cases were qualitatively inspected. Results: The artifact detection model produced a Dice score of 0.958 +- 0.008. The inpainting model was able to recreate images with a structural similarity index of 0.988 +- 0.012. With the chamber segmentations improved surface Dice scores from 0.684 +- 0.247 to 0.964 +- 0.067 and the Hausdorff distance reduced from 3.4 +- 3.9 mm to 0.7 +- 0.7 mm. The inpainting model's use on cardiac patient CTs was visually inspected and the artifact-inpainted images were visually plausible. Conclusion: We successfully developed two deep models to detect and inpaint metal artifacts in cardiac CT images.

physics.med-ph