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Hoseok Lee

Publications and source records attributed to Hoseok Lee.

3 recordsLinked to original sources

MnemoDyn: Learning Resting State Dynamics from 40K FMRI sequences

We present a dynamical-systems based model for resting-state functional magnetic resonance imaging (rs-fMRI), trained on a dataset of roughly 40K rs-fMRI sequences covering a wide variety of public and available-by-permission datasets. While most existing proposals use transformer backbones, we utilize multi-resolution temporal modeling of the dynamics across parcellated brain regions. We show that MnemoDyn is compute efficient and generalizes very well across diverse populations and scanning protocols. When benchmarked against current state-of-the-art transformer-based approaches, MnemoDyn consistently delivers superior reconstruction quality. Overall, we find that with such large-scale pre-training on (non-proprietary) rs-fMRI datasets, we get a highly performant model for various downstream tasks. Our results also provide evidence of the efficacy of the model on small sample size studies which has implications for neuroimaging studies at large where resting state fMRI is a commonly acquired imaging modality.

cs.LG

Residual-Guided Expert Specialization for Incomplete Multimodal Learning

As real-world prediction systems often face missing modalities at inference, incomplete multimodal learning (IML) remains a practical challenge. While prior methods aim to learn representations robust to missing inputs, representations from incomplete modalities inevitably deviate from their full-modality counterparts due to missing evidence. To explicitly leverage these deviations, we propose MARS (Missingness-Aware Residual-guided Specialization), a mixture-of-experts framework that guides expert specialization based on how representations are reshaped by missingness. By contrasting task representations derived from incomplete inputs with their complete counterparts during training, we derive a privileged residual signal that captures this representational gap. The residual signal guides a residual router to assign samples to experts specialized for the corresponding deviation patterns. In parallel, a feature router learns to imitate this routing behavior using only incomplete inputs, enabling deployment without access to full modalities. To mitigate this train-test router gap, we develop a discrepancy-aware noise regularization that adaptively perturbs the residual router's decisions when the feature router deviates, enhancing expert robustness under imperfect imitation. Experiments on multimodal classification (CASIA-SURF, CREMA-D, UPMC Food-101) and segmentation (MCubeS) under missing scenarios show that MARS consistently surpasses baselines while remaining efficient and extensible to diverse backbones and tasks.

cs.CV

Set-Inclusive Uncertainty Modeling for Robust Brain Tumor Segmentation

Multimodal MRI is essential for accurate brain tumor segmentation. However, acquiring all modalities at inference is often challenging in practice, which causes intrinsic uncertainty due to unavoidable information loss. Without modeling this uncertainty, existing methods encode incomplete evidence into deterministic representations that appear plausible but lack reliability. In this regime, we propose a probabilistic representation framework that models representations as Gaussian distributions, where their mean captures task information and their variance measures uncertainty from missing evidence. To make variance reflect information deficiency, we regularize the mean from each partial configuration toward its full-modality counterpart, while scaling the variance with the discrepancy between their aligned means. We further introduce a set-inclusive strategy that exploits the hierarchical structure of modality subsets and enforces an ordering constraint to maintain their consistent uncertainty relationships. Extensive experiments on BraTS 2018 and 2020 demonstrate that our approach offers superior performance over baselines across diverse missing-modality scenarios. Code and model checkpoint are available at https://github.com/atlas-sky/SIUM.

cs.CV