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Hua Li

Publications and source records attributed to Hua Li.

At least 109 records · Page 6Linked to original sources

Towards Compact and Real-Time Terahertz Dual-Comb Spectroscopy Employing a Self-Detection Scheme

Due to its fast and high resolution characteristics, dual-comb spectroscopy has attracted an increasing amount of interest since its first demonstration. In the terahertz frequency range where abundant absorption lines (finger prints) of molecules are located, multiheterodyne spectroscopy that employs the dual-comb technique shows an advantage in real-time spectral detection over the traditional Fourier transform infrared or time domain spectroscopies. Here, we demonstrate compact terahertz dual-comb spectroscopy based on quantum cascade lasers (QCLs). In our experiment, two free-running QCLs generate approximately 120 GHz wide combs centered at 4.2 THz, with slightly different repetition frequencies. We observe that $\sim$490 nW terahertz power coupling of one laser into the other suffices for laser-self-detecting the dual-comb spectrum that is registered by a microwave spectrum analyzer. Furthermore, we demonstrate practical terahertz transmission dual-comb spectroscopy with our device, by implementing a short air path at room temperature. Spectra are shown of semiconductor samples and of moist air, the latter allowing rapid monitoring of the relative humidity. Our devices should be readily extendable to perform imaging, microscopy and near-field microscopy in the terahertz regime.

physics.optics↗

Dual affine moment invariants

Affine transformation is one of the most common transformations in nature, which is an important issue in the field of computer vision and shape analysis. And affine transformations often occur in both shape and color space simultaneously, which can be termed as Dual-Affine Transformation (DAT). In general, we should derive invariants of different data formats separately, such as 2D color images, 3D color objects, or even higher-dimensional data. To the best of our knowledge, there is no general framework to derive invariants for all of these data formats. In this paper, we propose a general framework to derive moment invariants under DAT for objects in M-dimensional space with N channels, which can be called dual-affine moment invariants (DAMI). Following this framework, we present the generating formula of DAMI under DAT for 3D color objects. Then, we instantiated a complete set of DAMI for 3D color objects with orders and degrees no greater than 4. Finally, we analyze the characteristic of these DAMI and conduct classification experiments to evaluate the stability and discriminability of them. The results prove that DAMI is robust for DAT. Our derivation framework can be applied to data in any dimension with any number of channels.

cs.CV↗

Viscosity Bound Violation in Viscoelastic Fermi Liquids

The anti-de Sitter/conformal field theory correspondence (AdS/CFT) has been used to determine a lower bound on the ratio of shear viscosity $\left(η\right)$ to entropy density $(s)$ for strongly-coupled field theories with a gravity dual. The conjectured universal lower bound, given as $η/s\geq\hbar/4πk_B$, is a measure of interaction strength in a quantum fluid where equality indicates a perfect quantum fluid. In this paper we study $η/s$ in a Fermi gas in the unitary limit. We show that in addition to a local minimum for $η/s$ at $T\approx 2T_c$ which obeys the lower bound, a more interesting result exists in the violation of the $η/s$ lower bound due to the superfluid fluctuations above $T_c$. To conclude, we examine the viscoelastic properties of the unitary Fermi gas. Previous work brought to light the connection between violation of the $η/s$ bound and a viscoelastic response in the context of holographic solids. We ultimately find that, in addition to holographic solids, all Fermi liquids with a viscoelastic response produced by superfluid fluctuations can violate the universal $η/s$ lower bound.

cond-mat.str-el↗

Magnetic resonance imaging of mean cell size in human breast tumors

Purpose: Cell size is a fundamental characteristic of all tissues, and changes in cell size in cancer reflect tumor status and response to treatments, such as apoptosis and cell cycle arrest. Unfortunately, cell size can only be obtained by pathologic evaluation of the tumor in the current standard of care. Previous imaging approaches can be implemented on only animal MRI scanners or require relatively long acquisition times that are undesirable for clinical imaging. There is a need to develop cell size imaging for clinics. Experimental Design: We propose a new method, IMPULSED (Imaging Microstructural Parameters Using Limited Spectrally Edited Diffusion) that can characterize mean cell sizes in solid tumors. We report the use of combined sequences with different gradient waveforms on human MRI and analytical equations that link DWI signals of real gradient waveforms and specific microstructural parameters such as cell size. We also describe comprehensive validations using computer simulations, cell experiments in vitro, and animal experiments in vivo and finally demonstrate applications in pre-operative breast cancer patients. Results: With fast acquisitions (~ 7 mins), IMPULSED can provide high-resolution (1.3 mm in-plane) mapping of mean cell size of human tumors in vivo on currently-available 3T MRI scanners. All validations suggest IMPULSED provide accurate and reliable measurements of mean cell size. Conclusion: The proposed IMPULSED method can assess cell size variations in the tumor of breast cancer patients, which may have the potential to assess early response to neoadjuvant therapy.

physics.bio-ph↗

Approximating the Ideal Observer and Hotelling Observer for binary signal detection tasks by use of supervised learning methods

It is widely accepted that optimization of medical imaging system performance should be guided by task-based measures of image quality (IQ). Task-based measures of IQ quantify the ability of an observer to perform a specific task such as detection or estimation of a signal (e.g., a tumor). For binary signal detection tasks, the Bayesian Ideal Observer (IO) sets an upper limit of observer performance and has been advocated for use in optimizing medical imaging systems and data-acquisition designs. Except in special cases, determination of the IO test statistic is analytically intractable. Markov-chain Monte Carlo (MCMC) techniques can be employed to approximate IO detection performance, but their reported applications have been limited to relatively simple object models. In cases where the IO test statistic is difficult to compute, the Hotelling Observer (HO) can be employed. To compute the HO test statistic, potentially large covariance matrices must be accurately estimated and subsequently inverted, which can present computational challenges. This work investigates supervised learning-based methodologies for approximating the IO and HO test statistics. Convolutional neural networks (CNNs) and single-layer neural networks (SLNNs) are employed to approximate the IO and HO test statistics, respectively. Numerical simulations were conducted for both signal-known-exactly (SKE) and signal-known-statistically (SKS) signal detection tasks. The performances of the supervised learning methods are assessed via receiver operating characteristic (ROC) analysis and the results are compared to those produced by use of traditional numerical methods or analytical calculations when feasible. The potential advantages of the proposed supervised learning approaches for approximating the IO and HO test statistics are discussed.

eess.SP↗

Automatic microscopic cell counting by use of deeply-supervised density regression model

Accurately counting cells in microscopic images is important for medical diagnoses and biological studies, but manual cell counting is very tedious, time-consuming, and prone to subjective errors, and automatic counting can be less accurate than desired. To improve the accuracy of automatic cell counting, we propose here a novel method that employs deeply-supervised density regression. A fully convolutional neural network (FCNN) serves as the primary FCNN for density map regression. Innovatively, a set of auxiliary FCNNs are employed to provide additional supervision for learning the intermediate layers of the primary CNN to improve network performance. In addition, the primary CNN is designed as a concatenating framework to integrate multi-scale features through shortcut connections in the network, which improves the granularity of the features extracted from the intermediate CNN layers and further supports the final density map estimation.

cs.CV↗

Automatic microscopic cell counting by use of unsupervised adversarial domain adaptation and supervised density regression

Accurate cell counting in microscopic images is important for medical diagnoses and biological studies. However, manual cell counting is very time-consuming, tedious, and prone to subjective errors. We propose a new density regression-based method for automatic cell counting that reduces the need to manually annotate experimental images. A supervised learning-based density regression model (DRM) is trained with annotated synthetic images (the source domain) and their corresponding ground truth density maps. A domain adaptation model (DAM) is built to map experimental images (the target domain) to the feature space of the source domain. By use of the unsupervised learning-based DAM and supervised learning-based DRM, a cell density map of a given target image can be estimated, from which the number of cells can be counted. Results from experimental immunofluorescent microscopic images of human embryonic stem cells demonstrate the promising performance of the proposed counting method.

cs.CV↗

Machine Learning Allows Calibration Models to Predict Trace Element Concentration in Soil with Generalized LIBS Spectra

Calibration models have been developed for determination of trace elements, silver for instance, in soil using laser-induced breakdown spectroscopy (LIBS). The major concern is the matrix effect. Although it affects the accuracy of LIBS measurements in a general way, the effect appears accentuated for soil because of large variation of chemical and physical properties among different soils. The purpose is to reduce its influence in such way an accurate and soil-independent calibration model can be constructed. At the same time, the developed model should efficiently reduce experimental fluctuations affecting measurement precision. A univariate model first reveals obvious influence of matrix effect and important experimental fluctuation. A multivariate model has been then developed. A key point is the introduction of generalized spectrum where variables representing the soil type are explicitly included. Machine learning has been used to develop the model. After a necessary pretreatment where a feature selection process reduces the dimension of raw spectrum accordingly to the number of available spectra, the data have been fed in to a back-propagation neuronal networks (BPNN) to train and validate the model. The resulted soilindependent calibration model allows average relative error of calibration (REC) and average relative error of prediction (REP) within the range of 5-6%.

physics.chem-ph↗

Differential and integral invariants under Mobius transformation

One of the most challenging problems in the domain of 2-D image or 3-D shape is to handle the non-rigid deformation. From the perspective of transformation groups, the conformal transformation is a key part of the diffeomorphism. According to the Liouville Theorem, an important part of the conformal transformation is the Mobius transformation, so we focus on Mobius transformation and propose two differential expressions that are invariable under 2-D and 3-D Mobius transformation respectively. Next, we analyze the absoluteness and relativity of invariance on them and their components. After that, we propose integral invariants under Mobius transformation based on the two differential expressions. Finally, we propose a conjecture about the structure of differential invariants under conformal transformation according to our observation on the composition of the above two differential invariants.

cs.GR↗

Convolutional neural network based automatic plaque characterization from intracoronary optical coherence tomography images

Optical coherence tomography (OCT) can provide high-resolution cross-sectional images for analyzing superficial plaques in coronary arteries. Commonly, plaque characterization using intra-coronary OCT images is performed manually by expert observers. This manual analysis is time consuming and its accuracy heavily relies on the experience of human observers. Traditional machine learning based methods, such as the least squares support vector machine and random forest methods, have been recently employed to automatically characterize plaque regions in OCT images. Several processing steps, including feature extraction, informative feature selection, and final pixel classification, are commonly used in these traditional methods. Therefore, the final classification accuracy can be jeopardized by error or inaccuracy within each of these steps. In this study, we proposed a convolutional neural network (CNN) based method to automatically characterize plaques in OCT images. Unlike traditional methods, our method uses the image as a direct input and performs classification as a single-step process. The experiments on 269 OCT images showed that the average prediction accuracy of CNN-based method was 0.866, which indicated a great promise for clinical translation.

cs.CV↗

Fast and Efficient Calculations of Structural Invariants of Chirality

Chirality plays an important role in physics, chemistry, biology, and other fields. It describes an essential symmetry in structure. However, chirality invariants are usually complicated in expression or difficult to evaluate. In this paper, we present five general three-dimensional chirality invariants based on the generating functions. And the five chiral invariants have four characteristics:(1) They play an important role in the detection of symmetry, especially in the treatment of 'false zero' problem. (2) Three of the five chiral invariants decode an universal chirality index. (3) Three of them are proposed for the first time. (4) The five chiral invariants have low order no bigger than 4, brief expression, low time complexity O(n) and can act as descriptors of three-dimensional objects in shape analysis. The five chiral invariants give a geometric view to study the chiral invariants. And the experiments show that the five chirality invariants are effective and efficient, they can be used as a tool for symmetry detection or features in shape analysis.

physics.comp-ph↗

Redefine the correlation coefficient by experiment methods

With the establishment of global biological monitor network and development of remote sensing technology, data won't be a limitation, but the variance brought by spatial heterogeneous and fractal will influence correlation coefficient significantly with the enlarged sample scale. Those impede us to find more intrinsic principle in ecology. Ecology is based on experiment, and the experiment methods won't change with spatial. In that condition, if we construct a system to evaluate the experimental difference, that may benefit the study in spatial ecology. In that condition, we give a synthesis discussion from the concept of data, experiment to analysis methods,and revise as well as develop correlation and regression method to make it suit the demand of spatial analysis. An experimental correlation system is established in this report.

stat.AP↗

Watch Me, but Don't Touch Me! Contactless Control Flow Monitoring via Electromagnetic Emanations

Trustworthy operation of industrial control systems depends on secure and real-time code execution on the embedded programmable logic controllers (PLCs). The controllers monitor and control the critical infrastructures, such as electric power grids and healthcare platforms, and continuously report back the system status to human operators. We present Zeus, a contactless embedded controller security monitor to ensure its execution control flow integrity. Zeus leverages the electromagnetic emission by the PLC circuitry during the execution of the controller programs. Zeus's contactless execution tracking enables non-intrusive monitoring of security-critical controllers with tight real-time constraints. Those devices often cannot tolerate the cost and performance overhead that comes with additional traditional hardware or software monitoring modules. Furthermore, Zeus provides an air-gap between the monitor (trusted computing base) and the target (potentially compromised) PLC. This eliminates the possibility of the monitor infection by the same attack vectors. Zeus monitors for control flow integrity of the PLC program execution. Zeus monitors the communications between the human-machine interface and the PLC, and captures the control logic binary uploads to the PLC. Zeus exercises its feasible execution paths, and fingerprints their emissions using an external electromagnetic sensor. Zeus trains a neural network for legitimate PLC executions, and uses it at runtime to identify the control flow based on PLC's electromagnetic emissions. We implemented Zeus on a commercial Allen Bradley PLC, which is widely used in industry, and evaluated it on real-world control program executions. Zeus was able to distinguish between different legitimate and malicious executions with 98.9% accuracy and with zero overhead on PLC execution by design.

cs.CR↗

Naturally Combined Shape-Color Moment Invariants under Affine Transformations

We proposed a kind of naturally combined shape-color affine moment invariants (SCAMI), which consider both shape and color affine transformations simultaneously in one single system. In the real scene, color and shape deformations always exist in images simultaneously. Simple shape invariants or color invariants can not be qualified for this situation. The conventional method is just to make a simple linear combination of the two factors. Meanwhile, the manual selection of weights is a complex issue. Our construction method is based on the multiple integration framework. The integral kernel is assigned as the continued product of the shape and color invariant cores. It is the first time to directly derive an invariant to dual affine transformations of shape and color. The manual selection of weights is no longer necessary, and both the shape and color transformations are extended to affine transformation group. With the various of invariant cores, a set of lower-order invariants are constructed and the completeness and independence are discussed detailedly. A set of SCAMIs, which called SCAMI24, are recommended, and the effectiveness and robustness have been evaluated on both synthetic and real datasets.

cs.CV↗

Image Projective Invariants

In this paper, we propose relative projective differential invariants (RPDIs) which are invariant to general projective transformations. By using RPDIs and the structural frame of integral invariant, projective weighted moment invariants (PIs) can be constructed very easily. It is first proved that a kind of projective invariants exists in terms of weighted integration of images, with relative differential invariants as the weight functions. Then, some simple instances of PIs are given. In order to ensure the stability and discriminability of PIs, we discuss how to calculate partial derivatives of discrete images more accurately. Since the number of pixels in discrete images before and after the geometric transformation may be different, we design the method to normalize the number of pixels. These ways enhance the performance of PIs. Finally, we carry out some experiments based on synthetic and real image datasets. We choose commonly used moment invariants for comparison. The results indicate that PIs have better performance than other moment invariants in image retrieval and classification. With PIs, one can compare the similarity between images under the projective transformation without knowing the parameters of the transformation, which provides a good tool to shape analysis in image processing, computer vision and pattern recognition.

cs.CV↗

4d isip: 4d implicit surface interest point detection

In this paper, we propose a new method to detect 4D spatiotemporal interest points though an implicit surface, we refer to as the 4D-ISIP. We use a 3D volume which has a truncated signed distance function(TSDF) for every voxel to represent our 3D object model. The TSDF represents the distance between the spatial points and object surface points which is an implicit surface representation. Our novelty is to detect the points where the local neighborhood has significant variations along both spatial and temporal directions. We established a system to acquire 3D human motion dataset using only one Kinect. Experimental results show that our method can detect 4D-ISIP for different human actions.

cs.CV↗

A Kind of Affine Weighted Moment Invariants

A new kind of geometric invariants is proposed in this paper, which is called affine weighted moment invariant (AWMI). By combination of local affine differential invariants and a framework of global integral, they can more effectively extract features of images and help to increase the number of low-order invariants and to decrease the calculating cost. The experimental results show that AWMIs have good stability and distinguishability and achieve better results in image retrieval than traditional moment invariants. An extension to 3D is straightforward.

cs.CV↗

Shape-Color Differential Moment Invariants under Affine Transformations

We propose the general construction formula of shape-color primitives by using partial differentials of each color channel in this paper. By using all kinds of shape-color primitives, shape-color differential moment invariants can be constructed very easily, which are invariant to the shape affine and color affine transforms. 50 instances of SCDMIs are obtained finally. In experiments, several commonly used color descriptors and SCDMIs are used in image classification and retrieval of color images, respectively. By comparing the experimental results, we find that SCDMIs get better results.

cs.CV↗