arXiv subjects

Huiyi Wu

Publications and source records attributed to Huiyi Wu.

3 recordsLinked to original sources

arXiv2026

A Mapping Sheath with Thermally Drawn Multi-Electrode Basket for Cardiac Electrophysiological Recording and Ablation Catheter Delivery

Cardiac arrhythmias, particularly atrial fibrillation, represent a major cardiovascular health burden and underscore the need for efficient and integrated strategies for electrical mapping and targeted therapy. Cardiac electrophysiology procedures depend on accurate identification of arrhythmogenic substrates followed by timely catheter ablation, but conventional diagnostic and therapeutic devices remain separate, often requiring repeated catheter exchanges and multiple access routes. Here, we report an adaptable strategy for functionalizing hollow-core sheaths with EP mapping capabilities, integrating multielectrode recording and ablation catheter delivery within a single compact platform. The device leverages thermal drawing to enable complex geometric fabrication, miniaturization, rapid prototyping, and scalable manufacturing of ultrathin electrode splines arranged circumferentially at the distal end to form an adjustable basket. The mapping sheath exhibited mechanical and electrophysiological properties suitable for intracardiac navigation and electrogram recording in bench-top evaluations, an in vitro left atrial phantom study, and ex vivo Langendorff-perfused porcine heart testing. In vivo porcine studies further demonstrated translational feasibility through vascular introduction, fluoroscopic visualization, intracardiac deployment, tissue contact, electrogram acquisition, and reconstruction of voltage and activation maps. These results support the development of intracardiac platforms with an adapted manufacturing approach, potentially guiding advances in agile cardiac mapping and ablation.

physics.med-ph↗

arXiv2025

Multi-Tiered Self-Contrastive Learning for Medical Microwave Radiometry (MWR) Breast Cancer Detection

Improving breast cancer detection and monitoring techniques is a critical objective in healthcare, driving the need for innovative imaging technologies and diagnostic approaches. This study introduces a novel multi-tiered self-contrastive model tailored for microwave radiometry (MWR) in breast cancer detection. Our approach incorporates three distinct models: Local-MWR (L-MWR), Regional-MWR (R-MWR), and Global-MWR (G-MWR), designed to analyze varying sub-regional comparisons within the breasts. These models are integrated through the Joint-MWR (J-MWR) network, which leverages self-contrastive results at each analytical level to improve diagnostic accuracy. Utilizing a dataset of 4,932 female patients, our research demonstrates the efficacy of our proposed models. Notably, the J-MWR model achieves a Matthew's correlation coefficient of 0.74 $\pm$ 0.018, surpassing existing MWR neural networks and contrastive methods. These findings highlight the potential of self-contrastive learning techniques in improving the diagnostic accuracy and generalizability for MWR-based breast cancer detection. This advancement holds considerable promise for future investigations into enabling point-of-care testing. The source code is available at: https://github.com/cgalaz01/self_contrastive_mwr.

eess.IV↗

arXiv2022

Tempera: Spatial Transformer Feature Pyramid Network for Cardiac MRI Segmentation

Assessing the structure and function of the right ventricle (RV) is important in the diagnosis of several cardiac pathologies. However, it remains more challenging to segment the RV than the left ventricle (LV). In this paper, we focus on segmenting the RV in both short (SA) and long-axis (LA) cardiac MR images simultaneously. For this task, we propose a new multi-input/output architecture, hybrid 2D/3D geometric spatial TransformEr Multi-Pass fEature pyRAmid (Tempera). Our feature pyramid extends current designs by allowing not only a multi-scale feature output but multi-scale SA and LA input images as well. Tempera transfers learned features between SA and LA images via layer weight sharing and incorporates a geometric target transformer to map the predicted SA segmentation to LA space. Our model achieves an average Dice score of 0.836 and 0.798 for the SA and LA, respectively, and 26.31 mm and 31.19 mm Hausdorff distances. This opens up the potential for the incorporation of RV segmentation models into clinical workflows.

eess.IV↗