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Huy-Hieu Pham

Publications and source records attributed to Huy-Hieu Pham.

At least 19 recordsLinked to original sources

Asymmetric Paired-Annotation Learning for Multi-Structure ULF Pediatric Brain MRI Segmentation

Portable ultra-low-field (ULF) MRI can expand access to pediatric neuroimaging, but segmentation at 0.064 T remains challenging because anatomical boundaries are weakly delineated, small structures may be only partially visible, and high-field references can be locally misregistered. The LISA 2026 Challenge provides two non-equivalent annotations reflecting different sources of anatomical evidence: a highfield-derived (HF) mask defining the scored target and a low-field-edited (LF) mask aligned with visible ULF anatomy. In this challenge report, we describe AURA, an nnU-Net-based asymmetric supervision strategy that treats these annotations as distinct observations rather than interchangeable ground truths. AURA anchors training to the HF mask and incorporates the LF mask through a bounded reliability gate based on label disagreement, boundaries, predictive uncertainty, class reliability, and training stage. On a 16-case development split, the HF-supervised baseline, AURA, and their ensemble achieved Dice scores of 0.7984, 0.7950, and 0.7988, respectively, while the ensemble achieved an HD95 of 1.8892 and an ASSD of 0.7855. These results provide a preliminary evaluation of AURA within the LISA 2026 Challenge and motivate further assessment on the hidden test set and external ULF cohorts. Our code and pretrained models are available at https://github.com/minhdang050806/ A-nnU-Net-based-asymmetric-supervision-strategy.

cs.CV

Candidate-Expanding Routing with Permutation-Stabilized Experts for Mixed-Format Medical VQA

Mixed-format medical visual question answering (VQA) requires stable option selection and machine-readable free-text output. The two formats fail differently: multiple-choice predictions can change with option symbols or positions, while clinically plausible open answers can fail automated evaluation when serialization is malformed. We address both challenges with an answer-text memory, a permutation-stabilized vision--language expert, and a sparse candidate- expanding router. The cyclic schedule follows prior work; our contribution is to make expert top-2 a routable candidate alongside memory and expert top-1. On a 1,403-case retrospective internal analysis, this expansion improves a matched binary router from 88.95% to 91.73% (+2.78 percentage points; 95% CI 1.57--3.99), with 56 rescued errors and 17 regressions. Oracle coverage rises from 90.31% to 96.15%, and the final submitted configuration reaches 92.23% on the same retrospective split. For open questions, strict generation and deterministic guards produce 475/475 schema- valid participant-facing outputs without repair, retry, or hard-gate failure. Visual ablations reveal substantial textual dependence. Candidate expansion supplies the principal controlled routing gain; open-path evidence establishes output-contract validity rather than clinical correctness in medical use or deployment.

cs.CV

Entity-Constrained CBCT Retrieval for Low-Resource Dental Record Completion

Completing dental records from cone-beam computed tomography (CBCT) is difficult when annotation is scarce and individual clinical fields are supported by different types of evidence. MMDental Task 3 requires seven-field record completion from only 50 labeled CBCT cases and scores the correctness of structured FDI positions and ICD codes; consequently, a visually plausible retrieved record can still be harmful when it introduces an unsupported entity. We propose Entity-Constrained CBCT-Guided Retrieval (ECCR), a parameter-free framework that separates evidence availability from evidence authority. A corpus-derived prior first supplies the complete record. A frozen 3D encoder retrieves image-conditioned Diagnosis evidence, which is appended only if it does not expand the prior FDI or ICD entity set, so the asserted entity set is invariant by construction. On public validation, ECCR reaches a weighted score of 0.3134, improving on both full-record multimodal retrieval (0.2237) and a static text-only prior (0.2915); the guard blocks 63.3% of retrieved candidates, each of which would otherwise have injected an FDI position or ICD code absent from the prior. On the final test evaluation, ECCR obtains 11.37 of a 97.4-point attainable maximum, securing second place overall. The result indicates that, in an extreme low-resource setting, controlling what multimodal evidence is allowed to modify can be more reliable than transferring an entire retrieved record.

cs.CV

Neurai-VN Benchmark: Standardized Machine Learning Models for Multimodal Digital Phenotyping in Mental Health Classification

Digital phenotyping (DP) using smartphones and wearable devices has emerged as a promising approach for assessing mental health, particularly depression and anxiety. However, progress remains difficult to evaluate because of heterogeneity across datasets and inconsistencies in preprocessing pipelines. In this work, we introduce a reproducible machine learning benchmark using the Neurai-VN dataset, a multimodal digital phenotyping dataset collected from 100 Vietnamese adults over two weeks. We define four binary classification tasks evaluated using standardized subject-wise cross-validation. Representative linear, tree-based, and neural baseline models are evaluated systematically across predefined feature-group configurations. Mean subject-level F1 scores across five cross-validation folds reached 0.71 for Healthy Control vs. Depression and Healthy Control vs. Clinical, while Healthy Control vs. Anxiety and Depression vs. Anxiety achieved 0.69 and 0.56, respectively. These baseline results provide reproducible baselines for future research on multimodal DP for mental health classification tasks. The code to reproduce the benchmark is available at https://github.com/neurai-vn/Neurai-VN-benchmark.

cs.LG

VISHC at PsyDefDetect: Mitigating Data Scarcity in Psychological Defense Classification with Context-Aware Synthetic Augmentation

Psychological defense mechanisms (PDMs) are unconscious cognitive processes that modulate how individuals perceive and respond to emotional distress. Automatically classifying PDMs from text is clinically valuable but severely hindered by data scarcity and class imbalance, challenges which generative augmentation alone cannot resolve without psychological grounding. In this work, we address these challenges in the PsyDefDetect shared task (BioNLP@ACL 2026) by proposing a context-aware synthetic augmentation framework combined with a hybrid classification model. Our hybrid model integrates contextual language representations with basic clinical features, along with 150 annotated defense items. Experiments demonstrate that definition quality in prompting directly governs generation fidelity and downstream performance. Our method surpasses DMRS Co-Pilot, reaching an accuracy of 58.26% (+40.25%) and a macro-F1 of 24.62% (+15.99%), thereby establishing a strong baseline for psychologically grounded defense mechanism classification in low-resource settings. Source code is available at: https://github.com/htdgv/CASA-PDC.

cs.CL

Who Gets Missed in the Tail? Thresholded Subgroup Underdiagnosis in Long-Tailed Chest X-ray Classification

In chest X-ray (CXR) classification, acceptable ranking performance can still leave rare-positive patients below threshold, especially within subgroups. We study this pre-deployment fairness problem as an audit question: after a long-tailed multi-label CXR model is converted from scores into decisions, who is missed? Across VinDr-CXR and MIMIC-CXR/CXR-LT, we use a diagnostic ladder to separate class-level long-tail losses, subgroup-aware weighting, group robustness, and threshold selection. On VinDr-CXR, group-tail weighting followed by tail-aware thresholding reduces tail FNR from 0.665 to 0.269, sex worst-group FNR from 0.705 to 0.157, and age worst-group FNR from 0.822 to 0.133, while macro-mAP increases from 0.611 to 0.635. On MIMIC-CXR/CXR-LT, the same score-to-threshold comparison reduces tail FNR from 0.866 to 0.741 and lowers worst-group FNR across sex, age, race, and insurance; residual missed-positive rates nevertheless remain high. Paired bootstrap contrasts on VinDr support the thresholded FNR reductions, and GroupDRO reference runs indicate that aggregate group robustness alone does not remove rare subgroup misses in this setting. The study supports a narrow audit claim: rare-label fairness in CXR depends jointly on the finding, subgroup, and operating threshold, not on label frequency or ranking metrics alone.

cs.LG

Single-Stage Hierarchical Rectification for Weakly Supervised Histopathology Segmentation

Existing weakly supervised semantic segmentation (WSSS) methods in computational pathology rely on a multi-stage paradigm: class activation map (CAM) generation, offline pseudo-mask refinement, and fully supervised retraining. While established, this decoupled approach presents fundamental limitations. The multi-stage process not only incurs high computational training costs but also suffers from error propagation: local texture biases in shallow CNN layers generate false-positive artifacts that subsequent refinement steps often fail to correct. To address these persistent challenges through a simple yet highly effective approach, we propose the Single-Stage Hierarchical Rectification (SSHR) framework. Rather than passively refining CAMs post-hoc, our method proactively purifies intermediate feature representations during the forward pass. We introduce a Hierarchical Feature Rectification Module (HFRM) that utilizes deep global semantic context to filter out local anomalies in shallow layers. This mechanism generates high-fidelity activation maps directly within a single training loop. Experiments on the LUAD-HistoSeg and BCSS datasets demonstrate that SSHR outperforms state-of-the-art multi-stage methods. Furthermore, SSHR reduces training duration by 2 to 5 times. This efficiency minimizes computational overhead and accelerates clinical translation for large-scale histopathology workflows. The code is available at: https://github.com/trongduc-nguyen/SSHR

cs.CV

EVL-ECG: Efficient ECG Interpretation With Multi-Aspect Heterogeneous Knowledge Distillation

High-fidelity ECG interpretation is increasingly reliant on massive foundation models, yet their deployment in clinical edge-care remains hindered by extreme computational demands. While knowledge distillation (KD) is a promising solution, traditional methods fail to capture the complex spatio-temporal dependencies of ECG signals when transferring knowledge across heterogeneous architectures. In this paper, we propose EVL-ECG, a framework specifically designed for cross-architecture distillation of cardiac diagnostic logic. EVL-ECG introduces three ECG-aware innovations: (1) Multi-Head Cross-Attention Alignment, which harmonizes architectural discrepancies to preserve fine-grained morphological features; (2) Optimal Transport-based Visual Feature Matching, utilizing optimal transport to maintain global structural relationships across ECG leads despite mismatched token representations; and (3) Geometric Intra-Architecture Relation Matching, which distills the latent diagnostic reasoning of the teacher model. Evaluations across ECG benchmarks demonstrate that EVL-ECG yields improvements of up to 2.4% AUC and 1.1% clinical accuracy over existing baselines. Notably, EVL-ECG establishes an efficient 2B-parameter ECG foundation model, suitable for resource-constrained clinical environments.

cs.CV

MIC: Maximizing Informational Capacity in Adaptive Representations via Isotropic Subspace Alignment

Although multi-scales representation learning enables elastic-dimension embeddings, nested subspaces often suffer from dimensional redundancy and spectral collapse. To address this, we introduce MIC, a framework that optimizes the geometric landscape of multi-granular embeddings through isotropic subspace alignment. MIC employs Soft Collapse Regularization (SCR) to mitigate redundancy between prefix and residual subspaces via cross-correlation penalties, alongside Spectral Isotropy Regularization (SIR) to ensure hyper-spherical uniformity in low-dimensional prefixes. By unifying these strategies through a self-distillation objective, MIC generates semantically dense representations that maintain high discriminative power. Our experiments demonstrate that MIC significantly outperforms standard baselines, particularly in high-compression scenarios where maintaining informational capacity is most critical.

cs.LG

CXR-LT 2026 Challenge: Multi-Center Long-Tailed and Zero Shot Chest X-ray Classification

Chest X-ray (CXR) interpretation is hindered by the long-tailed distribution of pathologies and the open-world nature of clinical environments. Existing benchmarks often rely on closed-set classes from a single institution, failing to capture the prevalence of rare diseases or the appearance of novel findings. To address this, we present the CXR-LT challenge. The first event, CXR-LT 2023, established a large-scale benchmark for long-tailed multi-label CXR classification and identified key challenges in rare disease recognition. CXR-LT 2024 further expanded the label space and introduced a zero-shot task to study generalization to unseen findings. Building on the success of CXR-LT 2023 and 2024, this third iteration of the benchmark introduces a multi-center dataset comprising over 145,000 images from PadChest and NIH Chest X-ray datasets. Additionally, all development and test sets in CXR-LT 2026 are annotated by radiologists, providing a more reliable and clinically grounded evaluation than report-derived labels. The challenge defines two core tasks this year: (1) Robust Multi-Label Classification on 30 known classes and (2) Open-World Generalization to 6 unseen (out-of-distribution) rare disease classes. This paper summarizes the overview of the CXR-LT 2026 challenge. We describe the data collection and annotation procedures, analyze solution strategies adopted by participating teams, and evaluate head-versus-tail performance, calibration, and cross-center generalization gaps. Our results show that vision-language foundation models improve both in-distribution and zero-shot performance, but detecting rare findings under multi-center shift remains challenging. Our study provides a foundation for developing and evaluating AI systems in realistic long-tailed and open-world clinical conditions.

cs.CV

HOT: Harmonic-Constrained Optimal Transport for Remote Photoplethysmography Domain Adaptation

Remote photoplethysmography (rPPG) enables non-contact physiological measurement from facial videos; however, its practical deployment is often hindered by substantial performance degradation under domain shift. While recent deep learning-based rPPG methods have achieved strong performance on individual datasets, they frequently overfit to appearance-related factors, such as illumination, camera characteristics, and color response, that vary significantly across domains. To address this limitation, we introduce frequency domain adaptation (FDA) as a principled strategy for modeling appearance variation in rPPG. By transferring low-frequency spectral components that encode domain-dependent appearance characteristics, FDA encourages rPPG models to learn invariance to appearance variations while retaining cardiac-induced signals. To further support physiologically consistent alignment under such appearance variation, we propose Harmonic-Constrained Optimal Transport (HOT), which leverages the harmonic property of cardiac signals to guide alignment between original and FDA-transferred representations. Extensive cross-dataset experiments demonstrate that the proposed FDA and HOT framework effectively enhances the robustness and generalization of rPPG models across diverse datasets.

cs.CV

BTS-rPPG: Orthogonal Butterfly Temporal Shifting for Remote Photoplethysmography

Remote photoplethysmography (rPPG) enables contactless physiological sensing from facial videos by analyzing subtle appearance variations induced by blood circulation. However, modeling the temporal dynamics of these signals remains challenging, as many deep learning methods rely on temporal shifting or convolutional operators that aggregate information primarily from neighboring frames, resulting in predominantly local temporal modeling and limited temporal receptive fields. To address this limitation, we propose BTS-rPPG, a temporal modeling framework based on Orthogonal Butterfly Temporal Shifting (BTS). Inspired by the butterfly communication pattern in the Fast Fourier Transform (FFT), BTS establishes structured frame interactions via an XOR-based butterfly pairing schedule, progressively expanding the temporal receptive field and enabling efficient propagation of information across distant frames. Furthermore, we introduce an orthogonal feature transfer mechanism (OFT) that filters the source feature with respect to the target context before temporal shifting, retaining only the orthogonal component for cross-frame transmission. This reduces redundant feature propagation and encourages complementary temporal interaction. Extensive experiments on multiple benchmark datasets demonstrate that BTS-rPPG improves long-range temporal modeling of physiological dynamics and consistently outperforms existing temporal modeling strategies for rPPG estimation.

cs.CV

Synergizing Deep Learning and Biological Heuristics for Extreme Long-Tail White Blood Cell Classification

Automated white blood cell (WBC) classification is essential for leukemia screening but remains challenged by extreme class imbalance, long-tail distributions, and domain shift, leading deep models to overfit dominant classes and fail on rare subtypes. We propose a hybrid framework for rare-class generalization that integrates a generative Pix2Pix-based restoration module for artifact removal, a Swin Transformer ensemble with MedSigLIP contrastive embeddings for robust representation learning, and a biologically-inspired refinement step using geometric spikiness and Mahalanobis-based morphological constraints to recover out-of-distribution predictions. Evaluated on the WBCBench 2026 challenge, our method achieves a Macro-F1 of 0.77139 on the private leaderboard, demonstrating strong performance under severe imbalance and highlighting the value of incorporating biological priors into deep learning for hematological image analysis. The code is available at https://github.com/trongduc-nguyen/WBCBench2026

cs.CV

CLEAR: Causal Learning Framework For Robust Histopathology Tumor Detection Under Out-Of-Distribution Shifts

Domain shift in histopathology, often caused by differences in acquisition processes or data sources, poses a major challenge to the generalization ability of deep learning models. Existing methods primarily rely on modeling statistical correlations by aligning feature distributions or introducing statistical variation, yet they often overlook causal relationships. In this work, we propose a novel causal-inference-based framework that leverages semantic features while mitigating the impact of confounders. Our method implements the front-door principle by designing transformation strategies that explicitly incorporate mediators and observed tissue slides. We validate our method on the CAMELYON17 dataset and a private histopathology dataset, demonstrating consistent performance gains across unseen domains. As a result, our approach achieved up to a 7% improvement in both the CAMELYON17 dataset and the private histopathology dataset, outperforming existing baselines. These results highlight the potential of causal inference as a powerful tool for addressing domain shift in histopathology image analysis.

cs.CV

Digital FAST: An AI-Driven Multimodal Framework for Rapid and Early Stroke Screening

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for automatic binary stroke screening based on data collected during the F.A.S.T. assessment. The proposed approach integrates complementary information from facial expressions, speech signals, and upper-body movements to enhance diagnostic robustness. Facial dynamics are represented using landmark based features and modeled with a Transformer architecture to capture temporal dependencies. Speech signals are converted into mel spectrograms and processed using an Audio Spectrogram Transformer, while upper-body pose sequences are analyzed with an MLP-Mixer network to model spatiotemporal motion patterns. The extracted modality specific representations are combined through an attention-based fusion mechanism to effectively learn cross modal interactions. Experiments conducted on a self-collected dataset of 222 videos from 37 subjects demonstrate that the proposed multimodal model consistently outperforms unimodal baselines, achieving 95.83% accuracy and a 96.00% F1-score. The model attains a strong balance between sensitivity and specificity and successfully detects all stroke cases in the test set. These results highlight the potential of multimodal learning and transfer learning for early stroke screening, while emphasizing the need for larger, clinically representative datasets to support reliable real-world deployment.

cs.CV

Handling Supervision Scarcity in Chest X-ray Classification: Long-Tailed and Zero-Shot Learning

Chest X-Ray (CXR) classification in clinical practice is often limited by imperfect supervision, arising from (i) extreme long-tailed multi-label disease distributions and (ii) missing annotations for rare or previously unseen findings. The CXR-LT 2026 challenge addresses these issues on a PadChest-based benchmark with a 36-class label space split into 30 in-distribution classes for training and 6 out-of-distribution (OOD) classes for zero-shot evaluation. We present task-specific solutions tailored to the distinct supervision regimes. For Task 1 (long-tailed multi-label classification), we adopt an imbalance-aware multi-label learning strategy to improve recognition of tail classes while maintaining stable performance on frequent findings. For Task 2 (zero-shot OOD recognition), we propose a prediction approach that produces scores for unseen disease categories without using any supervised labels or examples from the OOD classes during training. Evaluated with macro-averaged mean Average Precision (mAP), our method achieves strong performance on both tasks, ranking first on the public leaderboard of the development phase. Code and pre-trained models are available at https://github.com/hieuphamha19/CXR_LT.

cs.CV

Graph-Theoretic Consistency for Robust and Topology-Aware Semi-Supervised Histopathology Segmentation

Semi-supervised semantic segmentation (SSSS) is vital in computational pathology, where dense annotations are costly and limited. Existing methods often rely on pixel-level consistency, which propagates noisy pseudo-labels and produces fragmented or topologically invalid masks. We propose Topology Graph Consistency (TGC), a framework that integrates graph-theoretic constraints by aligning Laplacian spectra, component counts, and adjacency statistics between prediction graphs and references. This enforces global topology and improves segmentation accuracy. Experiments on GlaS and CRAG demonstrate that TGC achieves state-of-the-art performance under 5-10% supervision and significantly narrows the gap to full supervision.

eess.IV

Learning Disentangled Stain and Structural Representations for Semi-Supervised Histopathology Segmentation

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data, poses major challenges for automated segmentation. To address this, we propose Color-Structure Dual-Student (CSDS), a novel semi-supervised segmentation framework designed to learn disentangled representations of stain appearance and tissue structure. CSDS comprises two specialized student networks: one trained on stain-augmented inputs to model chromatic variation, and the other on structure-augmented inputs to capture morphological cues. A shared teacher network, updated via Exponential Moving Average (EMA), supervises both students through pseudo-labels. To further improve label reliability, we introduce stain-aware and structure-aware uncertainty estimation modules that adaptively modulate the contribution of each student during training. Experiments on the GlaS and CRAG datasets show that CSDS achieves state-of-the-art performance in low-label settings, with Dice score improvements of up to 1.2% on GlaS and 0.7% on CRAG at 5% labeled data, and 0.7% and 1.4% at 10%. Our code and pre-trained models are available at https://github.com/hieuphamha19/CSDS.

cs.CV