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Hyunkyung Han

Publications and source records attributed to Hyunkyung Han.

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Loss Invariance Determines What Concept Layers Encode: Volume Grounding in Echocardiography

Objective: Concept bottleneck models route prediction through interpretable intermediate variables, and their validity is normally judged by how accurately those variables are predicted. We ask whether that judgement is sufficient, using left ventricular volumes as the concepts underlying ejection fraction estimation from echocardiographic video. Methods: A video transformer encoder was trained on a publicly available echocardiography dataset. End-systolic and end-diastolic volumes formed a concept layer from which ejection fraction was computed analytically, with no residual path to the output. We compared training under an ejection fraction objective alone against training with additional supervision of the volumes in millilitres, and evaluated both on 1276 held-out studies. Results: The concept bottleneck did not increase ejection fraction error relative to direct regression, at 6.89 against 7.13 mean absolute error. Without volume supervision, however, the spread of predicted volumes collapsed to 0.1 millilitres against reference spreads of 35.7 and 45.7 millilitres, while correlation was partly preserved. We show that this follows from an invariance property of the objective: ejection fraction is a ratio and is unchanged when both volumes are rescaled, so the loss determines the concept layer only up to scale. Supervision in absolute units reduced volume error from 89.8 to 25.8 millilitres at a cost of 0.4 in ejection fraction error. Conclusion: Concept accuracy alone can conceal a concept layer that carries no physical scale. Significance: Interpretable intermediate variables in clinical models should be validated against the invariance structure of the training objective, not only against prediction accuracy.

cs.AI

Ablation-Corrected Evaluation of Attribution Maps in Echocardiographic Ejection-Fraction Models

Attribution maps for echocardiographic ejection-fraction models are evaluated by their overlap with an expert left-ventricular annotation, compared against a chance level that is computed from an area ratio rather than measured. We measure it. Two architectures trained on the same task attain overlap at 3.55 and 4.20 times measured chance, an eighteen percent difference a reader would take as the size of the gap between them. It is not. Replacing the annotated ventricle with a composition-matched surrogate changes one model's prediction six times more than replacing an equal-area control region and the other's twice, a factor of three; on sixty-two percent of cases for the second, neither the ventricle nor the attributed region moves the prediction at all. The reliability of this measurement, from two independent intervention batches, is 0.90 to 0.98. Overlap does not track the difference: scored against an ablation-derived label of which cases the model depends on the ventricle for, it reaches an area under the curve of 0.52 and 0.67. The design of the ablation also determines its answer, since ablating only the two annotated frames leaves the ventricle indistinguishable from a control region while ablating across all frames does not. A pediatric cohort reproduces all of these. We give the measured chance level, the symmetric-ablation protocol, the reliability estimate, and the ablation-prediction score as things to report alongside overlap.

cs.CV

QWERTY: Training-Free Motion Control via Query-Warped Video Diffusion Transformers

Video diffusion transformers (DiTs) generate high-fidelity and temporally coherent videos, yet motion control remains implicit, primarily relying on text prompts. As a result, achieving desired motion often requires extensive prompt engineering and repeated resampling. While fine-tuning models with additional spatial prompts (e.g., bounding boxes or point trajectories) enables explicit control, it demands substantial data curation and computation, and may compromise the generative capabilities of pretrained models. Consequently, training-free motion control using such spatial prompts has been explored in U-Net-based video diffusion models, but remains largely unexplored for DiTs. We introduce QWERTY, a training-free framework that enables flexible motion control in pretrained image-to-video DiTs via user-defined object warping and optical flow. We carefully manipulate the 3D full attention of DiTs by warping the frame-invariant semantic subspace of queries. We find that the noise predicted by the query-warped DiT naturally guides the diffusion trajectory toward the desired motion, and further show that leveraging this noise as self-guidance for latent optimization improves control stability and visual quality. Experiments show that QWERTY achieves the most effective motion control among existing training-free approaches on a recent image-to-video DiT, with performance comparable to fine-tuning-based methods.

cs.CV

Mono-Modalizing Extremely Heterogeneous Multi-Modal Medical Image Registration

In clinical practice, imaging modalities with functional characteristics, such as positron emission tomography (PET) and fractional anisotropy (FA), are often aligned with a structural reference (e.g., MRI, CT) for accurate interpretation or group analysis, necessitating multi-modal deformable image registration (DIR). However, due to the extreme heterogeneity of these modalities compared to standard structural scans, conventional unsupervised DIR methods struggle to learn reliable spatial mappings and often distort images. We find that the similarity metrics guiding these models fail to capture alignment between highly disparate modalities. To address this, we propose M2M-Reg (Multi-to-Mono Registration), a novel framework that trains multi-modal DIR models using only mono-modal similarity while preserving the established architectural paradigm for seamless integration into existing models. We also introduce GradCyCon, a regularizer that leverages M2M-Reg's cyclic training scheme to promote diffeomorphism. Furthermore, our framework naturally extends to a semi-supervised setting, integrating pre-aligned and unaligned pairs only, without requiring ground-truth transformations or segmentation masks. Experiments on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset demonstrate that M2M-Reg achieves up to 2x higher DSC than prior methods for PET-MRI and FA-MRI registration, highlighting its effectiveness in handling highly heterogeneous multi-modal DIR. Our code is available at https://github.com/MICV-yonsei/M2M-Reg.

cs.CV

Rethinking Random Masking in Self-Distillation on ViT

Vision Transformers (ViTs) have demonstrated remarkable performance across a wide range of vision tasks. In particular, self-distillation frameworks such as DINO have contributed significantly to these advances. Within such frameworks, random masking is often utilized to improve training efficiency and introduce regularization. However, recent studies have raised concerns that indiscriminate random masking may inadvertently eliminate critical semantic information, motivating the development of more informed masking strategies. In this study, we explore the role of random masking in the self-distillation setting, focusing on the DINO framework. Specifically, we apply random masking exclusively to the student's global view, while preserving the student's local views and the teacher's global view in their original, unmasked forms. This design leverages DINO's multi-view augmentation scheme to retain clean supervision while inducing robustness through masked inputs. We evaluate our approach using DINO-Tiny on the mini-ImageNet dataset and show that random masking under this asymmetric setup yields more robust and fine-grained attention maps, ultimately enhancing downstream performance.

cs.CV

Optimal path for Biomedical Text Summarization Using Pointer GPT

Biomedical text summarization is a critical tool that enables clinicians to effectively ascertain patient status. Traditionally, text summarization has been accomplished with transformer models, which are capable of compressing long documents into brief summaries. However, transformer models are known to be among the most challenging natural language processing (NLP) tasks. Specifically, GPT models have a tendency to generate factual errors, lack context, and oversimplify words. To address these limitations, we replaced the attention mechanism in the GPT model with a pointer network. This modification was designed to preserve the core values of the original text during the summarization process. The effectiveness of the Pointer-GPT model was evaluated using the ROUGE score. The results demonstrated that Pointer-GPT outperformed the original GPT model. These findings suggest that pointer networks can be a valuable addition to EMR systems and can provide clinicians with more accurate and informative summaries of patient medical records. This research has the potential to usher in a new paradigm in EMR systems and to revolutionize the way that clinicians interact with patient medical records.

cs.CL

Capsule Neural Networks as Noise Stabilizer for Time Series Data

Capsule Neural Networks utilize capsules, which bind neurons into a single vector and learn position equivariant features, which makes them more robust than original Convolutional Neural Networks. CapsNets employ an affine transformation matrix and dynamic routing with coupling coefficients to learn robustly. In this paper, we investigate the effectiveness of CapsNets in analyzing highly sensitive and noisy time series sensor data. To demonstrate CapsNets robustness, we compare their performance with original CNNs on electrocardiogram data, a medical time series sensor data with complex patterns and noise. Our study provides empirical evidence that CapsNets function as noise stabilizers, as investigated by manual and adversarial attack experiments using the fast gradient sign method and three manual attacks, including offset shifting, gradual drift, and temporal lagging. In summary, CapsNets outperform CNNs in both manual and adversarial attacked data. Our findings suggest that CapsNets can be effectively applied to various sensor systems to improve their resilience to noise attacks. These results have significant implications for designing and implementing robust machine learning models in real world applications. Additionally, this study contributes to the effectiveness of CapsNet models in handling noisy data and highlights their potential for addressing the challenges of noise data in time series analysis.

cs.LG

CardioCaps: Attention-based Capsule Network for Class-Imbalanced Echocardiogram Classification

Capsule Neural Networks (CapsNets) is a novel architecture that utilizes vector-wise representations formed by multiple neurons. Specifically, the Dynamic Routing CapsNets (DR-CapsNets) employ an affine matrix and dynamic routing mechanism to train capsules and acquire translation-equivariance properties, enhancing its robustness compared to traditional Convolutional Neural Networks (CNNs). Echocardiograms, which capture moving images of the heart, present unique challenges for traditional image classification methods. In this paper, we explore the potential of DR-CapsNets and propose CardioCaps, a novel attention-based DR-CapsNet architecture for class-imbalanced echocardiogram classification. CardioCaps comprises two key components: a weighted margin loss incorporating a regression auxiliary loss and an attention mechanism. First, the weighted margin loss prioritizes positive cases, supplemented by an auxiliary loss function based on the Ejection Fraction (EF) regression task, a crucial measure of cardiac function. This approach enhances the model's resilience in the face of class imbalance. Second, recognizing the quadratic complexity of dynamic routing leading to training inefficiencies, we adopt the attention mechanism as a more computationally efficient alternative. Our results demonstrate that CardioCaps surpasses traditional machine learning baseline methods, including Logistic Regression, Random Forest, and XGBoost with sampling methods and a class weight matrix. Furthermore, CardioCaps outperforms other deep learning baseline methods such as CNNs, ResNets, U-Nets, and ViTs, as well as advanced CapsNets methods such as EM-CapsNets and Efficient-CapsNets. Notably, our model demonstrates robustness to class imbalance, achieving high precision even in datasets with a substantial proportion of negative cases.

cs.CV