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Ibraheem Hamdi

Publications and source records attributed to Ibraheem Hamdi.

4 recordsLinked to original sources

Foundation Models in Biomedical Imaging: Turning Hype into Reality

Foundation models (FMs) are driving a prominent shift in biomedical imaging from task-specific models to unified backbone models for diverse tasks. This opens an avenue to integrate imaging, pathology, clinical records, and genomics data into a composite system. However, this vision contrasts sharply with modern medicine's trajectory toward more granular sub-specialization. This tension, coupled with data scarcity, domain heterogeneity, and limited interpretability, creates a gap between benchmark success and real-world clinical value. We argue that the immediate role of FMs lies in augmenting, not replacing, clinical expertise. To separate hype from reality, we introduce REAL-FM (Real-world Evaluation and Assessment of Foundation Models), a multi-dimensional framework for assessing data, technical readiness, clinical value, workflow integration, and responsible AI. Using REAL-FM, we find that while FMs excel in pattern recognition, they fall short in causal reasoning, domain robustness, and safety. Clinical translation is hindered by scarce representative data for model training, unverified generalization beyond oversimplified benchmark settings, and a lack of prospective outcome-based validation. We further examine FM reasoning paradigms, including sequential logic, spatial understanding, and symbolic domain knowledge. We envision that the path forward lies not in a monolithic medical oracle, but in coordinated subspecialist AI systems that are transparent, safe, and clinically grounded.

q-bio.QM

Automatic Quality Assessment of First Trimester Crown-Rump-Length Ultrasound Images

Fetal gestational age (GA) is vital clinical information that is estimated during pregnancy in order to assess fetal growth. This is usually performed by measuring the crown-rump-length (CRL) on an ultrasound image in the Dating scan which is then correlated with fetal age and growth trajectory. A major issue when performing the CRL measurement is ensuring that the image is acquired at the correct view, otherwise it could be misleading. Although clinical guidelines specify the criteria for the correct CRL view, sonographers may not regularly adhere to such rules. In this paper, we propose a new deep learning-based solution that is able to verify the adherence of a CRL image to clinical guidelines in order to assess image quality and facilitate accurate estimation of GA. We first segment out important fetal structures then use the localized structures to perform a clinically-guided mapping that verifies the adherence of criteria. The segmentation method combines the benefits of Convolutional Neural Network (CNN) and the Vision Transformer (ViT) to segment fetal structures in ultrasound images and localize important fetal landmarks. For segmentation purposes, we compare our proposed work with UNet and show that our CNN/ViT-based method outperforms an optimized version of UNet. Furthermore, we compare the output of the mapping with classification CNNs when assessing the clinical criteria and the overall acceptability of CRL images. We show that the proposed mapping is not only explainable but also more accurate than the best performing classification CNNs.

cs.CV

Breaking Down the Hierarchy: A New Approach to Leukemia Classification

The complexities inherent to leukemia, multifaceted cancer affecting white blood cells, pose considerable diagnostic and treatment challenges, primarily due to reliance on laborious morphological analyses and expert judgment that are susceptible to errors. Addressing these challenges, this study presents a refined, comprehensive strategy leveraging advanced deep-learning techniques for the classification of leukemia subtypes. We commence by developing a hierarchical label taxonomy, paving the way for differentiating between various subtypes of leukemia. The research further introduces a novel hierarchical approach inspired by clinical procedures capable of accurately classifying diverse types of leukemia alongside reactive and healthy cells. An integral part of this study involves a meticulous examination of the performance of Convolutional Neural Networks (CNNs) and Vision Transformers (ViTs) as classifiers. The proposed method exhibits an impressive success rate, achieving approximately 90\% accuracy across all leukemia subtypes, as substantiated by our experimental results. A visual representation of the experimental findings is provided to enhance the model's explainability and aid in understanding the classification process.

cs.CV

Hyperparameter Optimization for COVID-19 Chest X-Ray Classification

Despite the introduction of vaccines, Coronavirus disease (COVID-19) remains a worldwide dilemma, continuously developing new variants such as Delta and the recent Omicron. The current standard for testing is through polymerase chain reaction (PCR). However, PCRs can be expensive, slow, and/or inaccessible to many people. X-rays on the other hand have been readily used since the early 20th century and are relatively cheaper, quicker to obtain, and typically covered by health insurance. With a careful selection of model, hyperparameters, and augmentations, we show that it is possible to develop models with 83% accuracy in binary classification and 64% in multi-class for detecting COVID-19 infections from chest x-rays.

eess.IV