arXiv subjects

Igor L. Chernyavsky

Publications and source records attributed to Igor L. Chernyavsky.

9 recordsLinked to original sources

arXiv2026

The evolution of a gas current injected into a curved axisymmetric porous channel

We investigate gas injection into axisymmetric water-saturated porous channels with Gaussian and parabolic profiles, as idealized models of underground gas storage in dome-shaped anticlines. Exploiting the slenderness of each channel, we derive an evolution equation for the gas/liquid interface using a composite asymptotic approximation that accommodates large channel slopes and has a simplified small-slope form describing spreading in weakly curved channels. In the high gas-mobility limit, in contrast with flat planar channels, buoyancy influences the dynamics through different mechanisms in each geometry. For gas injected steadily into a Gaussian channel, buoyancy can continually affect the flow due to the attenuation of the gas velocity caused by axisymmetry. In parabolic channels, the increasing channel slope ensures that buoyancy eventually influences the flow, at a timescale depending on injection rate and fluid properties. Asymptotic analysis of the parabolic-channel flow reveals five temporal regimes, each with multiple spatial regions and a distinct spreading rate, reflecting the evolving spatiotemporal competition between injection and buoyancy. Initially, a thin film of gas spreads along the upper boundary; the channel slope and elongation of the film then generate a hydrostatic pressure gradient, which strengthens until buoyancy arrests the upper contact line and thickens the film. Beneath the film, liquid then drains until the interface flattens under buoyancy. Analytical solutions of reduced-order models capture interface evolution and contact-line motion through each regime and are validated against full numerical simulations. These results have implications for subsurface hydrogen and CO$_2$ storage, where a horizontal interface that advances vertically enhances both safety and storage efficiency.

physics.flu-dyn↗

arXiv2026

Compaction in a deformable porous cylinder with elastic boundaries

Perfusion of soft materials such as biological tissue or hydrogels is essential for the functioning of organ and laboratory systems such as chromatographic columns and bioreactors. Inspired by these applications, we model fluid-driven compaction in a long, thin cylindrical porous medium bounded by an impermeable elastic membrane and study how flow regimes relate to elastic parameters. Using a Lagrangian formulation of Darcy flow coupled to small-strain linear elasticity with porosity dependent permeability and elastic moduli, we perform an asymptotic reduction in the small aspect ratio limit and obtain a leading-order nonlinear diffusion equation for the porosity, which we solve numerically. Whereas rigid boundaries produce a compaction plateau, compliant walls exhibit, at most, an intermediate plateau beyond which the flow increases once the imposed pressure becomes comparable to the product of membrane stiffness and initial porosity. When the membrane is less stiff than the porous medium, flow rate can exceed that expected for a rigid medium. A parameter space map distinguishes regimes where plateau and breakthrough occur, where the steady flow rate is below (sub-Darcy) or above (super-Darcy) the undeformable-medium prediction, and delineates the small-strain domain in which the theory applies. An asymptotic solution for negligible gravity captures the departure from the plateau and yields compact expressions for effective permeability and flow rate.

physics.flu-dyn↗

arXiv2026

Dynamics of a compressible gas injected into a confined porous layer

Underground gas storage is a critical technology in global efforts to mitigate climate change. In particular, hydrogen storage offers a promising solution for integrating renewable energy into the power grid. When injected into the subsurface, hydrogen's low viscosity compared to the resident brine causes a bubble of hydrogen trapped beneath caprock to spread rapidly into an aquifer through release of a thin gas layer above the brine, complicating recovery. In long aquifers, the large viscous pressure drop between source and outlet induces significant pressure variations, potentially leading to substantial density changes in the injected gas. To examine the role of gas compressibility in the spreading dynamics, we use long-wave theory to derive coupled nonlinear evolution equations for the gas pressure and gas/liquid interface height, focusing on the limit of long domains, weak gas compressibility and low gas/liquid viscosity ratio. Simulations are supplemented with a comprehensive asymptotic analysis of parameter regimes. Unlike the near-incompressible limit, in which gas spreading rates are dictated by the source strength and viscosity ratio, and compressive effects are transient, we show how compression of the main gas bubble can generate dynamic pressure changes that are coupled to those in the thin gas layer that spreads over the liquid, with compressive effects having a sustained influence along the layer. This coupling allows compressibility to reduce spreading rates and gas pressures. We characterise this behaviour via a set of low-order models that reveal dominant scalings, highlighting the role of compressibility in mediating the evolution of the gas layer.

physics.flu-dyn↗

arXiv2025

A functional exchange shunt in the umbilical cord: the role of coiling in solute and heat transfer

The umbilical cord plays a critical role in delivering nutrients and oxygen from the placenta to the fetus through the umbilical vein, while the two umbilical arteries carry deoxygenated blood with waste products back to the placenta. Although solute exchange in the placenta has been extensively studied, exchange within the cord tissue has not been investigated. Here, we explore the hypothesis that the coiled structure of the umbilical cord could strengthen diffusive coupling between the arteries and the vein, resulting in a functional shunt. We calculate the diffusion of solutes, such as oxygen, and heat in the umbilical cord to quantify how this shunt is affected by vascular configuration within the cord. We demonstrate that the shunt is enhanced by coiling and vessel proximity. Furthermore, our model predicts that typical vascular configurations of the human cord tend to minimise shunting, which could otherwise disrupt thermal regulation of the fetus. We also show that the exchange, amplified by coiling, can provide additional oxygen supply to the cord tissue surrounding the umbilical vessels.

q-bio.TO↗

arXiv2022

Advection-dominated transport past isolated disordered sinks: stepping beyond homogenization

We investigate the transport of a solute past isolated sinks in a bounded domain when advection is dominant over diffusion, evaluating the effectiveness of homogenization approximations when sinks are distributed uniformly randomly in space. Corrections to such approximations can be non-local, non-smooth and non-Gaussian, depending on the physical parameters (a Péclet number Pe, assumed large, and a Damköhler number Da) and the compactness of the sinks. In one spatial dimension, solute distributions develop a staircase structure for large Pe, with corrections being better described with credible intervals than with traditional moments. In two and three dimensions, solute distributions are near-singular at each sink (and regularized by sink size), but their moments can be smooth as a result of ensemble averaging over variable sink locations. We approximate corrections to a homogenization approximation using a moment-expansion method, replacing the Green's function by its free-space form, and test predictions against simulation. We show how, in two or three dimensions, the leading-order impact of disorder can be captured in a homogenization approximation for the ensemble mean concentration through a modification to Da that grows with diminishing sink size.

physics.flu-dyn↗

arXiv2019

Quantifying the impact of tissue metabolism on solute transport in feto-placental microvascular networks

The primary exchange units in the human placenta are terminal villi, in which fetal capillary networks are surrounded by a thin layer of villous tissue, separating fetal from maternal blood. To understand how the complex spatial structure of villi influences their function, we use an image-based theoretical model to study the effect of tissue metabolism on the transport of solutes from maternal blood into the fetal circulation. For solute that is taken up under first-order kinetics, we show that the transition between flow-limited and diffusion-limited transport depends on two new dimensionless parameters defined in terms of key geometric quantities, with strong solute uptake promoting flow-limited transport conditions. We present a simple algebraic approximation for solute uptake rate as a function of flow conditions, metabolic rate and villous geometry. For oxygen, accounting for nonlinear kinetics using physiological parameter values, our model predicts that villous metabolism does not significantly impact oxygen transfer to fetal blood, although the partitioning of fluxes between the villous tissue and the capillary network depends strongly on the flow regime.

q-bio.TO↗

arXiv2019

Physical and geometric determinants of transport in feto-placental microvascular networks

Across mammalian species, solute exchange takes place in complex microvascular networks. In the human placenta, the primary exchange units are terminal villi that contain disordered networks of fetal capillaries and are surrounded externally by maternal blood. Here we show how the irregular internal structure of a terminal villus determines its exchange capacity for a wide range of solutes. Distilling geometric features into three scalar parameters, obtained from image analysis and computational fluid dynamics, we capture archetypal features of the the structure-function relationship of terminal villi using a simple algebraic approximation, revealing transitions between flow- and diffusion-limited transport at vessel and network levels. Our theory accommodates countercurrent effects, incorporates nonlinear blood rheology and offers an efficient method for testing network robustness. Our results show how physical estimates of solute transport, based on carefully defined geometrical statistics, provide a viable method for linking placental structure and function, and offer a framework for assessing transport in other microvascular systems.

physics.bio-ph↗

arXiv2016

Image-Based Modeling of Blood Flow and Oxygen Transfer in Feto-Placental Capillaries

During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer in feto-placental capillaries by converting three-dimensional representations of villous and capillary surfaces, reconstructed from confocal laser scanning microscopy, to finite-element meshes, and calculating values of vascular flow resistance and total oxygen transfer. The relationship between the total oxygen transfer rate and the pressure drop through the capillary is shown to be captured across a wide range of pressure drops by physical scaling laws and an upper bound on the oxygen transfer rate. A regression equation is introduced that can be used to estimate the oxygen transfer in a capillary using the vascular resistance. Two techniques for quantifying the effects of statistical variability, experimental uncertainty and pathological placental structure on the calculated properties are then introduced. First, scaling arguments are used to quantify the sensitivity of the model to uncertainties in the geometry and the parameters. Second, the effects of localized dilations in fetal capillaries are investigated using an idealized axisymmetric model, to quantify the possible effect of pathological placental structure on oxygen transfer. The model predicts how, for a fixed pressure drop through a capillary, oxygen transfer is maximized by an optimal width of the dilation. The results could explain the prevalence of fetal hypoxia in cases of delayed villous maturation, a pathology characterized by a lack of the vasculo-syncytial membranes often seen in conjunction with localized capillary dilations.

q-bio.TO↗

arXiv2006

Mathematical model for blood flow autoregulation by endothelium-derived relaxing factor

The fluid shear stress is an important regulator of the cardiovascular system via the endothelium-derived relaxing factor (EDRF) that is Nitric Oxide. This mechanism involves biochemical reactions in an arterial wall. The autoregulation process is managed by the vascular tonus and gives the negative feedback for the shear stress changing. A new mathematical model for the autoregulation of a blood flow through arteria under the constant transmural pressure is presented. Endothelium-derived relaxing factor Nitric Oxide, the multi-layer structure of an arterial wall, and kinetic-diffusion processes are taken into consideration. The limit case of the thin-wall artery is analytically studied. The stability condition for a stationary point of the linearized system is given. The exact stationary solutions of the origin system are found. The numerical simulation for the autoregulation system is presented. It is shown the arteria adaptation to an initial radial perturbation and the transition of the system to new equilibrium state in response on the blood flow changing.

physics.bio-ph↗