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Ilya O. Ryzhov

Publications and source records attributed to Ilya O. Ryzhov.

10 recordsLinked to original sources

Fully sequential Gaussian process regression for preference learning

We study continuous global optimization problems in which the objective function cannot be directly evaluated; rather, we observe only which of two selected design points appears to perform better, subject to noise. Such comparisons complicate the use of Gaussian process regression because they yield non-Gaussian posteriors. We consider a fully sequential approximation, based on moment-matching, that yields a fast closed-form update of the metamodel's mean and covariance. We then propose DOVE, a fully sequential sampling policy that combines an information gain criterion with randomized sampling designed to control error accumulation. Under fairly standard regularity conditions, we prove convergence rates for both statistical error and expected simple regret that depend on kernel smoothness. To our knowledge, these are the first such rates for fully sequential approximate Bayesian inference in continuous global optimization.

cs.LG↗

Quantile optimization in semidiscrete optimal transport

Optimal transport is the problem of designing a joint distribution for two random variables with fixed marginals. In virtually the entire literature on this topic, the objective is to minimize expected cost. This paper is the first to study a variant in which the goal is to minimize a quantile of the cost, rather than the mean. For the semidiscrete setting, where one distribution is continuous and the other is discrete, we derive a complete characterization of the optimal transport plan and develop simulation-based methods to efficiently compute it. One particularly novel aspect of our approach is the efficient computation of a tie-breaking rule that preserves marginal distributions. In the context of geographical partitioning problems, the optimal plan is shown to produce a novel geometric structure.

econ.EM↗

Semidiscrete optimal transport with unknown costs

Semidiscrete optimal transport is a challenging generalization of the classical transportation problem in linear programming. The goal is to design a joint distribution for two random variables (one continuous, one discrete) with fixed marginals, in a way that minimizes expected cost. We formulate a novel variant of this problem in which the cost functions are unknown, but can be learned through noisy observations; however, only one function can be sampled at a time. We develop a semi-myopic algorithm that couples online learning with stochastic approximation, and prove that it achieves optimal convergence rates, despite the non-smoothness of the stochastic gradient and the lack of strong concavity in the objective function.

econ.EM↗

Individual and group fairness in geographical partitioning

Socioeconomic segregation often arises in school districting and other contexts, causing some groups to be over- or under-represented within a particular district. This phenomenon is closely linked with disparities in opportunities and outcomes. We formulate a new class of geographical partitioning problems in which the population is heterogeneous, and it is necessary to ensure fair representation for each group at each facility. We prove that the optimal solution is a novel generalization of the additively weighted Voronoi diagram, and we propose a simple and efficient algorithm to compute it, thus resolving an open question dating back to Dvoretzky et al. (1951). The efficacy and potential for practical insight of the approach are demonstrated in a realistic case study involving seven demographic groups and $78$ district offices.

econ.EM↗

Optimal Simulation Budget Allocation Under Unknown Sampling Variance

The ranking and selection problem is a popular framework in the simulation literature for studying optimal information collection. We study a version of this problem in which the simulation output for each design is normally distributed with both its mean and variance being unknown. Using a Bayesian representation of the probability of correct selection, which allows us to explicitly model uncertainty about the variance, we provide a theoretical characterization of the optimal allocation of the simulation budget. Prior work on optimal budget allocation was unable to distinguish between known and unknown sampling variance. We show the impact of this type of uncertainty on the allocation, and design new sequential procedures that can be guaranteed to learn the optimal allocation asymptotically without the need for tuning or forced exploration.

math.OC↗

Digital Twin Calibration with Model-Based Reinforcement Learning

This paper presents a novel methodological framework, called the Actor-Simulator, that incorporates the calibration of digital twins into model-based reinforcement learning for more effective control of stochastic systems with complex nonlinear dynamics. Traditional model-based control often relies on restrictive structural assumptions (such as linear state transitions) and fails to account for parameter uncertainty in the model. These issues become particularly critical in industries such as biopharmaceutical manufacturing, where process dynamics are complex and not fully known, and only a limited amount of data is available. Our approach jointly calibrates the digital twin and searches for an optimal control policy, thus accounting for and reducing model error. We balance exploration and exploitation by using policy performance as a guide for data collection. This dual-component approach provably converges to the optimal policy, and outperforms existing methods in extensive numerical experiments based on the biopharmaceutical manufacturing domain.

cs.LG↗

Policy Optimization in Dynamic Bayesian Network Hybrid Models of Biomanufacturing Processes

Biopharmaceutical manufacturing is a rapidly growing industry with impact in virtually all branches of medicines. Biomanufacturing processes require close monitoring and control, in the presence of complex bioprocess dynamics with many interdependent factors, as well as extremely limited data due to the high cost of experiments as well as the novelty of personalized bio-drugs. We develop a novel model-based reinforcement learning framework that can achieve human-level control in low-data environments. The model uses a dynamic Bayesian network to capture causal interdependencies between factors and predict how the effects of different inputs propagate through the pathways of the bioprocess mechanisms. This enables the design of process control policies that are both interpretable and robust against model risk. We present a computationally efficient, provably convergence stochastic gradient method for optimizing such policies. Validation is conducted on a realistic application with a multi-dimensional, continuous state variable.

cs.AI↗

Optimal data-driven hiring with equity for underrepresented groups

We present a data-driven prescriptive framework for fair decisions, motivated by hiring. An employer evaluates a set of applicants based on their observable attributes. The goal is to hire the best candidates while avoiding bias with regard to a certain protected attribute. Simply ignoring the protected attribute will not eliminate bias due to correlations in the data. We present a hiring policy that depends on the protected attribute functionally, but not statistically, and we prove that, among all possible fair policies, ours is optimal with respect to the firm's objective. We test our approach on both synthetic and real data, and find that it shows great practical potential to improve equity for underrepresented and historically marginalized groups.

econ.EM↗

Personalized Multimorbidity Management for Patients with Type 2 Diabetes Using Reinforcement Learning of Electronic Health Records

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong potential to improve health outcomes relative to current clinical practice. In this paper, we modeled glycemia, blood pressure and cardiovascular disease (CVD) risk as health outcomes using a retrospective cohort of 16,665 patients with type 2 diabetes from New York University Langone Health ambulatory care electronic health records in 2009 to 2017. We trained a RL prescription algorithm that recommends a treatment regimen optimizing patients' cumulative health outcomes using their individual characteristics and medical history at each encounter. The RL recommendations were evaluated on an independent subset of patients. The results demonstrate that the proposed personalized reinforcement learning prescriptive framework for type 2 diabetes yielded high concordance with clinicians' prescriptions and substantial improvements in glycemia, blood pressure, cardiovascular disease risk outcomes.

cs.CY↗

A New Optimal Stepsize For Approximate Dynamic Programming

Approximate dynamic programming (ADP) has proven itself in a wide range of applications spanning large-scale transportation problems, health care, revenue management, and energy systems. The design of effective ADP algorithms has many dimensions, but one crucial factor is the stepsize rule used to update a value function approximation. Many operations research applications are computationally intensive, and it is important to obtain good results quickly. Furthermore, the most popular stepsize formulas use tunable parameters and can produce very poor results if tuned improperly. We derive a new stepsize rule that optimizes the prediction error in order to improve the short-term performance of an ADP algorithm. With only one, relatively insensitive tunable parameter, the new rule adapts to the level of noise in the problem and produces faster convergence in numerical experiments.

math.OC↗