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Iman Salehi

Publications and source records attributed to Iman Salehi.

9 recordsLinked to original sources

A Context-aware Gated Convex Mixtures of LSTM Experts for Nonlinear System Identification

This work addresses nonlinear and nonstationary system identification using one-step-ahead prediction on the nonlinear autoregressive moving average benchmark with ten-step memory (NARMA-10). Baseline models, including autoregressive models with exogenous input (ARX), nonlinear ARX using a multilayer perceptron (NARX--MLP), and a single long short-term memory network (LSTM), are used to contextualize prediction performance. To improve robustness, multiple LSTM experts are combined through a convex mixture. A standard adaptive convex mixture updates the mixing weights using an error-driven rule with simplex projection, but this mechanism is reactive, hand-tuned, and not end-to-end learnable. The proposed method introduces a context-aware end-to-end mixture-of-experts (MoE) framework in which a differentiable softmax gating network learns context-aware mixing weights jointly with the expert parameters. On stationary NARMA-10, the proposed MoE gating approach achieves performance comparable to the adaptive convex mixture. Under regime-switching dynamics, a controlled frozen-experts ablation isolates the mixing-weight update mechanism and shows that the MoE gate significantly improves robustness, achieving approximately fivefold lower overall test error and about two-and-a-half-fold lower after-switch error.

eess.SY

Introduction to Quantum Ophthalmology

Quantum technologies are rapidly advancing across multiple research domains, with a growing impact on biomedical imaging and sensing. We examine their emerging role in ophthalmology through four complementary directions: photon-limited retinal imaging, correlation based imaging, nanoscale optical probes, and quantum-limited visual perception. Advances in optical coherence tomography and single-photon detection enable imaging under strict photon budget constraints, reducing phototoxicity while preserving image quality. Correlation-based approaches, including ghost imaging, offer alternative strategies for image formation in low-light and scattering environments, although practical implementation remains limited by detection efficiency and acquisition time. In parallel, nanoscale optical platforms such as quantum dots provide tunable and photostable probes for enhanced contrast and targeted delivery, with ongoing challenges related to biocompatibility and clinical translation. Finally, experiments at the single-photon level and with structured light fields demonstrate how the visual system itself operates near physical detection limits and can be probed using controlled optical states. While many of these approaches remain at an early stage, they collectively illustrate how quantum and quantum-inspired methods may augment current ophthalmic imaging and diagnostic technologies while providing new tools for studying visual function under well-defined physical constraints.

physics.med-ph

Test-retest Reliability of Psychophysical Tasks Using Structured Light-Induced Entoptic Phenomena

Structured light (SL)-induced polarization perception presents a promising method for the early detection of macular diseases such as age-related macular degeneration. We investigated the test-retest reliability of a psychophysical task using SL-based stimuli to induce entoptic patterns in individuals with healthy vision. Twenty-eight participants underwent thorough eye examinations to confirm they had healthy eyes and good vision (logMAR BCVA ~0.00). Of these, 25 participants (n=50 eyes) aged 21 to 75 completed two identical tasks separated by 1 to 14 days. Using SL-based stimuli that produced a rotating entoptic pattern containing 22 azimuthal brushes, we measured the retinal eccentricity threshold $R_T$ at which participants could reliably identify the direction of rotation by varying the size of a central obstruction. This threshold reflects the visual angle of the pattern for each participant. We calculated the reliability coefficient (intraclass correlation coefficient, ICC) using a two-way mixed-effects model and conducted a Bland-Altman analysis to assess test-retest reliability. The ICC was 0.83 [95% CI: 0.62 - 0.93] for right eyes (RE) and 0.93 [95% CI: 0.84 - 0.97] for left eyes (LE), indicating good reliability. The Bland-Altman analysis showed a mean difference of -0.32° (SD: 1.51) and -0.12° (SD: 1.03) for RE and LE respectively between the first and second sessions, with limits of agreement ranging from -3.28° to 2.64° and -2.14° to 1.89° for RE and LE respectively, confirming strong agreement and no significant bias. These results demonstrate that SL-based psychophysical tasks are a reliable method for assessing polarization perception, potentially improving screening for diseases affecting macular health.

physics.med-ph

Topological Expansion of Boehm's Brushes via Structured Light

We report a novel entoptic phenomenon in which the classical two-lobed Boehm's brushes are transformed into a multi-lobed structure by projecting spin-orbit coupled light onto the human retina. These structured beams, composed of non-separable superpositions of circular polarization and orbital angular momentum (OAM), produce azimuthally modulated entoptic patterns through polarization-dependent scattering in the retina. Unlike Haidinger's brushes, which arise from dichroic absorption in the macula, the observed effect is driven by angular variations in scattering strength relative to the local polarization direction. In regions where scattering centers exhibit polarization orientations that converge toward a common point, their combined contributions reinforce one another, producing brighter and more sharply defined entoptic lobes whose number and orientation vary systematically with the topology of the spin-orbit stimulus. Psychophysical measurements across retinal eccentricities from 0.5$^\circ$ to 4$^\circ$ in eleven participants revealed that contrast detection thresholds decreased exponentially with eccentricity, consistent with polarization-sensitive scattering by isotropic structures in the non-foveal retinal regions. From the psychophysical fits, the mean eccentricity at which the entoptic pattern reached a 50 % threshold was $r_{50} = 1.03^\circ$ with a 95 % confidence interval of [0.72, 1.34]$^\circ$, indicating that the spin-orbit-induced entoptic structure becomes perceptually robust at approximately 1$^\circ$ retinal eccentricity. Together, these findings demonstrate that spin-orbit light modulates scattering-based visual phenomena in previously unrecognized ways, enabling new approaches for probing retinal structure and visual processing using topological features of light.

physics.optics

Eye dominance and testing order effects in the circularly-oriented macular pigment optical density measurements that rely on the perception of structured light-based stimuli

Psychophysical discrimination of structured light (SL) stimuli may be useful in screening for various macular disorders, including degenerative macular diseases. The circularly-oriented macular pigment optical density (coMPOD), calculated from the discrimination performance of SL-induced entoptic phenomena, may reveal a novel functional biomarker of macular health. In this study, we investigated the potential influence of eye dominance and testing order effects on SL-based stimulus perception, factors that potentially influence the sensitivity of screening tests based on SL technology. A total of 28 participants (aged 18-38 years) were selected for the study after undergoing a comprehensive eye examination. A psychophysical task was performed where various SL-based entoptic images with multiple azimuthal fringes rotating with a specific temporal frequency were projected onto the participants' retinas. By occluding the central areas of entoptic images, we measured the retinal eccentricity ($R$) of the perceivable area of the stimuli. The slope of the coMPOD profile ($a$-value) was calculated for each participant using a spatiotemporal sensitivity model that takes into account the perceptual threshold measurements of structured light stimuli with varying spatial densities and temporal frequencies. The Pearson correlation coefficient between eye dominance and testing order effects was $r=0.8$ ($p<0.01$). The Bland-Altman plots for both factors indicated zero bias. The results indicate repeatable measurements for both eyes, implying minimal impact from eye dominance and testing order on SL-based stimulus perception. The results provide a foundation for future studies exploring the clinical utility of SL tools in eye health.

q-bio.NC

Characterizing the circularly-oriented macular pigment using spatiotemporal sensitivity to structured light entoptic phenomena

The macular pigment (MP) in the radially-oriented Henle fibers that surround the foveola enables the ability to perceive the orientation of polarized blue light through an entoptic phenomena known as the Haidinger's brush. The MP has been linked to eye diseases and central field dysfunctions, most notably age-related macular degeneration (AMD), a globally leading cause of irreversible blindness. Recent integration of structured light techniques into vision science has allowed for the development of more selective and versatile entoptic probes of eye health that provide interpretable thresholds. For example, it enabled the use of variable spatial frequencies and arbitrary obstructions in the presented stimuli. Additionally, it expanded the 2° retinal eccentricity extent of the Haidinger's brush to 5° for a similar class of fringe-based stimuli. In this work, we develop a spatiotemporal sensitivity model that maps perceptual thresholds of entoptic phenomenon to the underlying MP structure that supports its perception. We therefore selectively characterize the circularly-oriented macular pigment optical density (coMPOD) rather than total MPOD as typically measured, providing an additional quantification of macular health. A study was performed where the retinal eccentricity thresholds were measured for five structured light stimuli with unique spatiotemporal frequencies. The results from fifteen healthy young participants indicate that the coMPOD is inversely proportional to retinal eccentricity in the range of 1.5° to 5.5°. Good agreement between the model and the collected data is found with a Pearson $χ^2$ fit statistic of 0.06. The presented techniques can be applied in novel early diagnostic tests for a variety of diseases related to macular degeneration such as AMD, macular telangiectasia, and pathological myopia.

physics.med-ph

Stitching Dynamic Movement Primitives and Image-based Visual Servo Control

Utilizing perception for feedback control in combination with Dynamic Movement Primitive (DMP)-based motion generation for a robot's end-effector control is a useful solution for many robotic manufacturing tasks. For instance, while performing an insertion task when the hole or the recipient part is not visible in the eye-in-hand camera, a learning-based movement primitive method can be used to generate the end-effector path. Once the recipient part is in the field of view (FOV), Image-based Visual Servo (IBVS) can be used to control the motion of the robot. Inspired by such applications, this paper presents a generalized control scheme that switches between motion generation using DMPs and IBVS control. To facilitate the design, a common state space representation for the DMP and the IBVS systems is first established. Stability analysis of the switched system using multiple Lyapunov functions shows that the state trajectories converge to a bound asymptotically. The developed method is validated by two real world experiments using the eye-in-hand configuration on a Baxter research robot.

cs.RO

Robust Learning of Nonlinear Dynamical Systems with Safety and Stability Properties

The paper presents a robust parameter learning methodology for identification of nonlinear dynamical system from data while satisfying safety and stability constraints in the context of learning from demonstration (LfD) methods. Extreme Learning Machines (ELM) is used to approximate the system model, whose parameters are learned subject to the safety and stability constraints obtained using zeroing barrier and Lyapunov-based stability analysis in the presence of model uncertainties and external disturbances. A constrained Quadratic Program (QP) is developed, which accounts for the ELM function reconstruction error, to estimate the ELM parameters. Furthermore, a robustness lemma is presented, which proves that the learned system model guarantees safety and stability in the presence of disturbances. The method is tested in simulations. Trajectory reconstruction accuracy of the method is compared against state-of-the-art LfD methods using swept error area (SEA) metric. Robustness of the learned model is tested by conducting Monte Carlo tests. The proposed method is implemented on a Baxter robot for a pick-and-place task where the robot is constrained to an ellipsoidal safety region.

eess.SY

Discrete-Time Nonlinear Systems Identification with Probabilistic Safety and Stability Constraints

This paper presents a discrete-time nonlinear system identification method while satisfying the stability and safety properties of the system with high probability. An Extreme Learning Machine (ELM) is used with a Gaussian assumption on the function reconstruction error. A quadratically constrained quadratic program (QCQP) is developed with probabilistic safety and stability constraints that are only required to be satisfied at sampled points inside the invariant region. The proposed method is validated using two simulation examples: a two degrees-of-freedom (DoF) robot manipulator with constraints on joint angles whose trajectories are guaranteed to remain inside a safe set and on motion trajectories data of a hand-drawn shape.

eess.SY