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Iordanis Kerenidis

Publications and source records attributed to Iordanis Kerenidis.

At least 19 recordsLinked to original sources

Scalable Quantum Machine Learning: Trainability, Expressivity and Efficiency

Designing scalable parameterized quantum circuits for machine learning faces three obstacles: barren plateaus, the absence of guarantees that the learned function class is classically hard, and prohibitive circuit evaluations per gradient step. We propose the unitary brick-wall: a $k$-particle fermionic architecture for nearest-neighbor hardware, combining Reconfigurable Beam Splitter gates with interleaved single-qubit phase gates and a non-Gaussian magic-state encoding, where $k$ is a tunable dial trading classical simulation hardness against training cost. Trainable. The brick-wall has dynamical Lie algebra $\mathfrak{u}(n)$ and is surjective onto $U(n)$ via Givens rotations, enabling Haar initialization. Two-body correlator readouts achieve gradient variance $Θ(k^3/n^5)$, polynomial in $n$ throughout $n-2k=Ω(n)$. Expressive. Classical hardness is controlled by $k$: best-known classical sampling algorithms run in time $2^{Θ(k)}\mathrm{poly}(n)$, worst-case #P-hardness holds from $k=n^ε$, and the average-case machinery of Fermion Sampling applies at $k=Θ(n)$. At our operating point $k=60$, best-known classical simulation exceeds $10^{24}$ operations at every $n$. Efficient. A multi-layer parallel parameter-shift rule computes all $O(n^2)$ gradients from $4kn$ circuit evaluations per gradient step, a factor $n/k$ reduction over the $4n^2$ evaluations of the standard rule, growing linearly with $n$ at fixed $k$. The unitary butterfly variant targets all-to-all hardware, with depth $2\log n$ and $(3/2)n\log n$ parameters, similar hardness guarantees, and $4k\log n$ evaluations per gradient step -- the same factor-$n/k$ reduction. Its trainability holds at two levels: absence of exponential barren plateaus is unconditional, while the sharp $Θ(k^3/n^5)$ rate holds under a two-particle approximate-2-design conjecture.

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Scalable On-Hardware Training of Quantum Neural Networks and Application to Clinical Data Imputation

Training quantum neural networks (QNNs) on quantum hardware is currently bottlenecked by the cost of gradient estimation: standard parameter-shift methods require a number of circuit evaluations that grows quadratically with the number of trainable parameters, making hardware-based optimisation impractical beyond small system sizes. In this work, we introduce a training framework that reduces this cost to logarithmic in the number of qubits, making gradient-based QNN optimisation feasible on near-term hardware at increasing scales. Our framework combines three co-designed ingredients: (i) a structured, subspace-preserving Butterfly circuit architecture with $O(n \log n)$ parameters and logarithmic depth; (ii) a layer-wise training strategy that confines on-hardware optimisation to one small, well-structured layer at a time; and (iii) a parallelised parameter-shift rule that exploits the commuting structure within each Butterfly layer to extract all gradients in a constant number of circuit executions. Together these reduce the number of distinct circuit evaluations per optimisation step from $O(n^2)$ to $O(\log n)$. We validate the framework on clinical data imputation using the MIMIC-III electronic health record dataset, a demanding benchmark sensitive to optimisation instability and model variance. Hybrid classical-quantum models are trained directly on IonQ Forte Enterprise trapped-ion hardware at 16 qubits without performance degradation relative to ideal or noisy simulation and via tensor-network simulation at 32 qubits, with 32-qubit inference executed on hardware. The resulting models match or exceed strong classical neural baselines in downstream patient survival prediction while exhibiting reduced variance across runs, demonstrating that the proposed framework enables practical, scalable QNN training under realistic hardware constraints.

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Experimental demonstration of quantum advantage in communication complexity for Euclidean distance problem

When considering the complexity of communication protocols, the aim is to perform a certain task with the minimum amount of communication resources, such as time and transmitted information. The use of quantum states may lead to an exponential advantage in the use of such resources. Here, we are interested in the task of calculating the Euclidean distance between two vectors representing real data sets. It has been previously shown that it is possible to obtain an advantage for this task based on quantum fingerprinting. This protocol is defined in the simultaneous message passing model of communication complexity, where the two parties do not communicate with each other but send data to a third party, and exploits practical fingerprints generated using trains of coherent state pulses instead of highly entangled qubit states that are hard to generate for large input sizes needed to demonstrate an exponential advantage. We perform a proof-of-principle experimental demonstration of the Euclidean distance protocol using amplitude modulation techniques for encoding non-binary data sets and high-performance superconducting nanowire single-photon detectors required to increase the accessible input size. We show a quantum advantage in transmitted information surpassing the best classical protocol for an input size of $10^8$, for diverse types of data sets, including those corresponding to real grayscale images, and with reasonable precision and error bounds. Our results highlight the potential of quantum communication complexity for use in a broad set of applications.

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Quantum Agents for Algorithmic Discovery

We introduce quantum agents trained by episodic, reward-based reinforcement learning to autonomously rediscover several seminal quantum algorithms and protocols. In particular, our agents learn: efficient logarithmic-depth quantum circuits for the Quantum Fourier Transform; Grover's search algorithm; optimal cheating strategies for strong coin flipping; and optimal winning strategies for the CHSH and other nonlocal games. The agents achieve these results directly through interaction, without prior access to known optimal solutions. This demonstrates the potential of quantum intelligence as a tool for algorithmic discovery, opening the way for the automated design of novel quantum algorithms and protocols.

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Quantum computing and artificial intelligence: status and perspectives

This white paper discusses and explores the various points of intersection between quantum computing and artificial intelligence (AI). It describes how quantum computing could support the development of innovative AI solutions. It also examines use cases of classical AI that can empower research and development in quantum technologies, with a focus on quantum computing and quantum sensing. The purpose of this white paper is to provide a long-term research agenda aimed at addressing foundational questions about how AI and quantum computing interact and benefit one another. It concludes with a set of recommendations and challenges, including how to orchestrate the proposed theoretical work, align quantum AI developments with quantum hardware roadmaps, estimate both classical and quantum resources - especially with the goal of mitigating and optimizing energy consumption - advance this emerging hybrid software engineering discipline, and enhance European industrial competitiveness while considering societal implications.

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Training-efficient density quantum machine learning

Quantum machine learning (QML) requires powerful, flexible and efficiently trainable models to be successful in solving challenging problems. We introduce density quantum neural networks, a model family that prepares mixtures of trainable unitaries, with a distributional constraint over coefficients. This framework balances expressivity and efficient trainability, especially on quantum hardware. For expressivity, the Hastings-Campbell Mixing lemma converts benefits from linear combination of unitaries into density models with similar performance guarantees but shallower circuits. For trainability, commuting-generator circuits enable density model construction with efficiently extractable gradients. The framework connects to various facets of QML including post-variational and measurement-based learning. In classical settings, density models naturally integrate the mixture of experts formalism, and offer natural overfitting mitigation. The framework is versatile - we uplift several quantum models into density versions to improve model performance, or trainability, or both. These include Hamming weight-preserving and equivariant models, among others. Extensive numerical experiments validate our findings.

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Improved Financial Forecasting via Quantum Machine Learning

Quantum algorithms have the potential to enhance machine learning across a variety of domains and applications. In this work, we show how quantum machine learning can be used to improve financial forecasting. First, we use classical and quantum Determinantal Point Processes to enhance Random Forest models for churn prediction, improving precision by almost 6%. Second, we design quantum neural network architectures with orthogonal and compound layers for credit risk assessment, which match classical performance with significantly fewer parameters. Our results demonstrate that leveraging quantum ideas can effectively enhance the performance of machine learning, both today as quantum-inspired classical ML solutions, and even more in the future, with the advent of better quantum hardware.

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Quantum Vision Transformers

In this work, quantum transformers are designed and analysed in detail by extending the state-of-the-art classical transformer neural network architectures known to be very performant in natural language processing and image analysis. Building upon the previous work, which uses parametrised quantum circuits for data loading and orthogonal neural layers, we introduce three types of quantum transformers for training and inference, including a quantum transformer based on compound matrices, which guarantees a theoretical advantage of the quantum attention mechanism compared to their classical counterpart both in terms of asymptotic run time and the number of model parameters. These quantum architectures can be built using shallow quantum circuits and produce qualitatively different classification models. The three proposed quantum attention layers vary on the spectrum between closely following the classical transformers and exhibiting more quantum characteristics. As building blocks of the quantum transformer, we propose a novel method for loading a matrix as quantum states as well as two new trainable quantum orthogonal layers adaptable to different levels of connectivity and quality of quantum computers. We performed extensive simulations of the quantum transformers on standard medical image datasets that showed competitively, and at times better performance compared to the classical benchmarks, including the best-in-class classical vision transformers. The quantum transformers we trained on these small-scale datasets require fewer parameters compared to standard classical benchmarks. Finally, we implemented our quantum transformers on superconducting quantum computers and obtained encouraging results for up to six qubit experiments.

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Quantum option pricing via the Karhunen-Loève expansion

We consider the problem of pricing discretely monitored Asian options over $T$ monitoring points where the underlying asset is modeled by a geometric Brownian motion. We provide two quantum algorithms with complexity poly-logarithmic in $T$ and polynomial in $1/ε$, where $ε$ is the additive approximation error. Our algorithms are obtained respectively by using an $O(\log T)$-qubit semi-digital quantum encoding of the Brownian motion that allows for exponentiation of the stochastic process and by analyzing classical Monte Carlo algorithms inspired by the semi-digital encodings. The best quantum algorithm obtained using this approach has complexity $\widetilde{O}(1/ε^{3})$ where the $\widetilde{O}$ suppresses factors poly-logarithmic in $T$ and $1/ε$. The methods proposed in this work generalize to pricing options where the underlying asset price is modeled by a smooth function of a sub-Gaussian process and the payoff is dependent on the weighted time-average of the underlying asset price.

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Improved clinical data imputation via classical and quantum determinantal point processes

Imputing data is a critical issue for machine learning practitioners, including in the life sciences domain, where missing clinical data is a typical situation and the reliability of the imputation is of great importance. Currently, there is no canonical approach for imputation of clinical data and widely used algorithms introduce variance in the downstream classification. Here we propose novel imputation methods based on determinantal point processes that enhance popular techniques such as the Multivariate Imputation by Chained Equations (MICE) and MissForest. Their advantages are two-fold: improving the quality of the imputed data demonstrated by increased accuracy of the downstream classification; and providing deterministic and reliable imputations that remove the variance from the classification results. We experimentally demonstrate the advantages of our methods by performing extensive imputations on synthetic and real clinical data. We also perform quantum hardware experiments by applying the quantum circuits for DPP sampling, since such quantum algorithms provide a computational advantage with respect to classical ones. We demonstrate competitive results with up to ten qubits for small-scale imputation tasks on a state-of-the-art IBM quantum processor. Our classical and quantum methods improve the effectiveness and robustness of clinical data prediction modeling by providing better and more reliable data imputations. These improvements can add significant value in settings demanding high precision, such as in pharmaceutical drug trials where our approach can provide higher confidence in the predictions made.

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Quantum Deep Hedging

Quantum machine learning has the potential for a transformative impact across industry sectors and in particular in finance. In our work we look at the problem of hedging where deep reinforcement learning offers a powerful framework for real markets. We develop quantum reinforcement learning methods based on policy-search and distributional actor-critic algorithms that use quantum neural network architectures with orthogonal and compound layers for the policy and value functions. We prove that the quantum neural networks we use are trainable, and we perform extensive simulations that show that quantum models can reduce the number of trainable parameters while achieving comparable performance and that the distributional approach obtains better performance than other standard approaches, both classical and quantum. We successfully implement the proposed models on a trapped-ion quantum processor, utilizing circuits with up to $16$ qubits, and observe performance that agrees well with noiseless simulation. Our quantum techniques are general and can be applied to other reinforcement learning problems beyond hedging.

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Connecting Quantum Cities: Simulation of a Satellite-Based Quantum Network

We present and analyse an architecture for a European-scale quantum network using satellite links to connect Quantum Cities, which are metropolitan quantum networks with minimal hardware requirements for the end users. Using NetSquid, a quantum network simulation tool based on discrete events, we assess and benchmark the performance of such a network linking distant locations in Europe in terms of quantum key distribution rates, considering realistic parameters for currently available or near-term technology. Our results highlight the key parameters and the limits of current satellite quantum communication links and can be used to assist the design of future missions. We also discuss the possibility of using high-altitude balloons as an alternative to satellites.

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Quantum Fourier Networks for Solving Parametric PDEs

Many real-world problems, like modelling environment dynamics, physical processes, time series etc., involve solving Partial Differential Equations (PDEs) parameterised by problem-specific conditions. Recently, a deep learning architecture called Fourier Neural Operator (FNO) proved to be capable of learning solutions of given PDE families for any initial conditions as input. However, it results in a time complexity linear in the number of evaluations of the PDEs while testing. Given the advancements in quantum hardware and the recent results in quantum machine learning methods, we exploit the running efficiency offered by these and propose quantum algorithms inspired by the classical FNO, which result in time complexity logarithmic in the number of evaluations and are, therefore, expected to be substantially faster than their classical counterpart. At their core, we use the unary encoding paradigm and orthogonal quantum layers and introduce a circuit to perform quantum Fourier transform in the unary basis. We propose three different quantum circuits to perform a quantum FNO. The proposals differ in their depth and their similarity to the classical FNO. We also benchmark our proposed algorithms on three PDE families, namely Burgers' equation, Darcy's flow equation and the Navier-Stokes equation. The results show that our quantum methods are comparable in performance to the classical FNO. We also perform an analysis on small-scale image classification tasks where our proposed algorithms are at par with the performance of classical CNNs, proving their applicability to other domains as well.

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Classical and Quantum Algorithms for Orthogonal Neural Networks

Orthogonal neural networks have recently been introduced as a new type of neural networks imposing orthogonality on the weight matrices. They could achieve higher accuracy and avoid evanescent or explosive gradients for deep architectures. Several classical gradient descent methods have been proposed to preserve orthogonality while updating the weight matrices, but these techniques suffer from long running times or provide only approximate orthogonality. In this paper, we introduce a new type of neural network layer called Pyramidal Circuit, which implements an orthogonal matrix multiplication. It allows for gradient descent with perfect orthogonality with the same asymptotic running time as a standard layer. This algorithm is inspired by quantum computing and can therefore be applied on a classical computer as well as on a near term quantum computer. It could become the building block for quantum neural networks and faster orthogonal neural networks.

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Medical image classification via quantum neural networks

Machine Learning provides powerful tools for a variety of applications, including disease diagnosis through medical image classification. In recent years, quantum machine learning techniques have been put forward as a way to potentially enhance performance in machine learning applications, both through quantum algorithms for linear algebra and quantum neural networks. In this work, we study two different quantum neural network techniques for medical image classification: first by employing quantum circuits in training of classical neural networks, and second, by designing and training quantum orthogonal neural networks. We benchmark our techniques on two different imaging modalities, retinal color fundus images and chest X-rays. The results show the promises of such techniques and the limitations of current quantum hardware.

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Quantum Methods for Neural Networks and Application to Medical Image Classification

Quantum machine learning techniques have been proposed as a way to potentially enhance performance in machine learning applications. In this paper, we introduce two new quantum methods for neural networks. The first one is a quantum orthogonal neural network, which is based on a quantum pyramidal circuit as the building block for implementing orthogonal matrix multiplication. We provide an efficient way for training such orthogonal neural networks; novel algorithms are detailed for both classical and quantum hardware, where both are proven to scale asymptotically better than previously known training algorithms. The second method is quantum-assisted neural networks, where a quantum computer is used to perform inner product estimation for inference and training of classical neural networks. We then present extensive experiments applied to medical image classification tasks using current state of the art quantum hardware, where we compare different quantum methods with classical ones, on both real quantum hardware and simulators. Our results show that quantum and classical neural networks generates similar level of accuracy, supporting the promise that quantum methods can be useful in solving visual tasks, given the advent of better quantum hardware.

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Experimental cheat-sensitive quantum weak coin flipping

As in modern communication networks, the security of quantum networks will rely on complex cryptographic tasks that are based on a handful of fundamental primitives. Weak coin flipping (WCF) is a significant such primitive which allows two mistrustful parties to agree on a random bit while they favor opposite outcomes. Remarkably, perfect information-theoretic security can be achieved in principle for quantum WCF. Here, we overcome conceptual and practical issues that have prevented the experimental demonstration of this primitive to date, and demonstrate how quantum resources can provide cheat sensitivity, whereby each party can detect a cheating opponent, and an honest party is never sanctioned. Such a property is not known to be classically achievable with information-theoretic security. Our experiment implements a refined, loss-tolerant version of a recently proposed theoretical protocol and exploits heralded single photons generated by spontaneous parametric down conversion, a carefully optimized linear optical interferometer including beam splitters with variable reflectivities and a fast optical switch for the verification step. High values of our protocol benchmarks are maintained for attenuation corresponding to several kilometers of telecom optical fiber.

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Quantum City: simulation of a practical near-term metropolitan quantum network

We present the architecture and analyze the applications of a metropolitan-scale quantum network that requires only limited hardware resources for end users. Using NetSquid, a quantum network simulation tool based on discrete events, we assess the performance of several quantum network protocols involving two or more users in various configurations in terms of topology, hardware and trust choices. Our analysis takes losses and errors into account and considers realistic parameters corresponding to present or near-term technology. Our results show that practical quantum-enhanced network functionalities are within reach today and can prepare the ground for further applications when more advanced technology becomes available.

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