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Irineo Cabreros

Publications and source records attributed to Irineo Cabreros.

3 recordsLinked to original sources

Causal models on probability spaces

We describe the interface between measure theoretic probability and causal inference by constructing causal models on probability spaces within the potential outcomes framework. We find that measure theory provides a precise and instructive language for causality and that consideration of the probability spaces underlying causal models offers clarity into central concepts of causal inference. By closely studying simple, instructive examples, we demonstrate insights into causal effects, causal interactions, matching procedures, and randomization. Additionally, we introduce a simple technique for visualizing causal models on probability spaces that is useful both for generating examples and developing causal intuition. Finally, we provide an axiomatic framework for causality and make initial steps towards a formal theory of general causal models.

math.ST

Dynamic Task Allocation for Crowdsourcing Settings

We consider the problem of optimal budget allocation for crowdsourcing problems, allocating users to tasks to maximize our final confidence in the crowdsourced answers. Such an optimized worker assignment method allows us to boost the efficacy of any popular crowdsourcing estimation algorithm. We consider a mutual information interpretation of the crowdsourcing problem, which leads to a stochastic subset selection problem with a submodular objective function. We present experimental simulation results which demonstrate the effectiveness of our dynamic task allocation method for achieving higher accuracy, possibly requiring fewer labels, as well as improving upon a previous method which is sensitive to the proportion of users to questions.

cs.LG

Detecting Community Structures in Hi-C Genomic Data

Community detection (CD) algorithms are applied to Hi-C data to discover new communities of loci in the 3D conformation of human and mouse DNA. We find that CD has some distinct advantages over pre-existing methods: (1) it is capable of finding a variable number of communities, (2) it can detect communities of DNA loci either adjacent or distant in the 1D sequence, and (3) it allows us to obtain a principled value of k, the number of communities present. Forcing k = 2, our method recovers earlier findings of Lieberman-Aiden, et al. (2009), but letting k be a parameter, our method obtains as optimal value k = 6, discovering new candidate communities. In addition to discovering large communities that partition entire chromosomes, we also show that CD can detect small-scale topologically associating domains (TADs) such as those found in Dixon, et al. (2012). CD thus provides a natural and flexible statistical framework for understanding the folding structure of DNA at multiple scales in Hi-C data.

q-bio.GN