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Jérémie Stym-Popper

Publications and source records attributed to Jérémie Stym-Popper.

3 recordsLinked to original sources

TSPFN: A Temporal Tabular Foundation Model for Physiological Time Series Classification

Designing models that generalize effectively in low- to medium-data regimes remains a primary challenge in medical machine learning, particularly for physiological time-series classification. While tabular foundation models such as TabPFN offer an attractive alternative to conventional fine-tuning through in-context learning, they are not designed to capture the temporal dependencies inherent to physiological signals. ~In this paper, we introduce TSPFN, a foundation model that redesigns TabPFN's architecture for time series data. TSPFN integrates structured temporal representations and positional embeddings to capture intra-sample temporal and channel dependencies. To fully leverage its spatio-temporal design, the model is pretrained on 140,000 real-world physiological time series across multiple medical domains. This yields a unified, generalizable framework capable of learning the specificities of medical time series. Experiments across diverse physiological benchmarks demonstrate that TSPFN consistently outperforms standard tabular baselines and TabPFN, and achieves superior cross-domain generalization compared to specialized deep time-series models. All our experiments, ablation studies, and pre-processing scheme are publicly available at https://github.com/Jeremstym/TSPFN

cs.LG↗

DAFTED: Decoupled Asymmetric Fusion of Tabular and Echocardiographic Data for Cardiac Hypertension Diagnosis

Multimodal data fusion is a key approach for enhancing diagnosis in medical applications. We propose an asymmetric fusion strategy starting from a primary modality and integrating secondary modalities by disentangling shared and modality-specific information. Validated on a dataset of 239 patients with echocardiographic time series and tabular records, our model outperforms existing methods, achieving an AUC over 90%. This improvement marks a crucial benchmark for clinical use.

cs.CV↗

Fusing Echocardiography Images and Medical Records for Continuous Patient Stratification

Deep learning enables automatic and robust extraction of cardiac function descriptors from echocardiographic sequences, such as ejection fraction or strain. These descriptors provide fine-grained information that physicians consider, in conjunction with more global variables from the clinical record, to assess patients' condition. Drawing on novel Transformer models applied to tabular data, we propose a method that considers all descriptors extracted from medical records and echocardiograms to learn the representation of a cardiovascular pathology with a difficult-to-characterize continuum, namely hypertension. Our method first projects each variable into its own representation space using modality-specific approaches. These standardized representations of multimodal data are then fed to a Transformer encoder, which learns to merge them into a comprehensive representation of the patient through the task of predicting a clinical rating. This stratification task is formulated as an ordinal classification to enforce a pathological continuum in the representation space. We observe the major trends along this continuum on a cohort of 239 hypertensive patients, providing unprecedented details in the description of hypertension's impact on various cardiac function descriptors. Our analysis shows that i) the XTab foundation model's architecture allows to reach outstanding performance (96.8% AUROC) even with limited data (less than 200 training samples), ii) stratification across the population is reproducible between trainings (within 5.7% mean absolute error), and iii) patterns emerge in descriptors, some of which align with established physiological knowledge about hypertension, while others could pave the way for a more comprehensive understanding of this pathology. Code is available at https://github.com/creatis-myriad/didactic.

cs.CV↗