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J. Lygeros

Publications and source records attributed to J. Lygeros.

3 recordsLinked to original sources

A Data-Driven Model Predictive Controller to manage epidemics: The case of SARS-CoV-2 in Mauritius

This work investigates the benefits of implementing a systematic approach to social isolation policies during epidemics. We develop a mixed integer data-driven model predictive control (MPC) scheme based on an SIHRD model which is identified from available data. The case of the spread of the SARS-CoV-2 virus (also known as COVID-19) in Mauritius is used as a reference point with data obtained during the period December 2021 to May 2022. The isolation scheme is designed with the control decision variable taking a finite set of values corresponding to the desired level of isolation. The control input is further restricted to shifting between levels only after a minimum amount of time. The simulation results validate our design, showing that the need for hospitalisation remains within the capacity of the health centres, with the number of deaths considerably reduced by raising the level of isolation for short periods of time with negligible social and economic impact. We also show that the introduction of additional isolation levels results in a smoother containment approach with a considerably reduced hospitalisation burden.

q-bio.PE

Simulated Annealing: Rigorous finite-time guarantees for optimization on continuous domains

Simulated annealing is a popular method for approaching the solution of a global optimization problem. Existing results on its performance apply to discrete combinatorial optimization where the optimization variables can assume only a finite set of possible values. We introduce a new general formulation of simulated annealing which allows one to guarantee finite-time performance in the optimization of functions of continuous variables. The results hold universally for any optimization problem on a bounded domain and establish a connection between simulated annealing and up-to-date theory of convergence of Markov chain Monte Carlo methods on continuous domains. This work is inspired by the concept of finite-time learning with known accuracy and confidence developed in statistical learning theory.

stat.ML