arXiv subjects

J. Sarma

Publications and source records attributed to J. Sarma.

3 recordsLinked to original sources

arXiv2025

Experimental evidence of production of directional muons from a laser-wakefield accelerator

We report on experimental evidence of the generation of directional muons from a laser-wakefield accelerator driven by a PW-class laser. The muons were generated following the interaction of a GeV-scale high-charge electron beam with a 2cm-thick Pb target and were detected using a Timepix3 detector placed behind a suitable shielding configuration. Data analysis indicates a $(99.1\pm0.5)$% confidence of muon detection over noise, in excellent agreement with numerical modelling. Extrapolation of the experimental setup to higher electron energies and charges suggests the potential to guide and separate from noise approximately $10^4$ muons/s onto cm$^2$-scale areas for applications using a 10 Hz PW laser. These results demonstrate the possibility of generating and transporting directional muon beams using high-power lasers and establish a foundation for the systematic application of laser-driven high-energy muon beams.

physics.acc-ph↗

arXiv2024

Single-pulse Gy-scale irradiation of biological cells at $10^{13}$ Gy/s average dose-rates from a laser-wakefield accelerator

We report on the first experimental characterization of a laser-wakefield accelerator able to deliver, in a single pulse, doses in excess of \unit[1]{Gy} on timescales of the order of a hundred femtoseconds, reaching unprecedented average dose-rates up to \unit[10$^{13}$]{Gy/s}. The irradiator is demonstrated to deliver doses tuneable up to \unit[2.2]{Gy} in a cm$^2$ area and with a high degree of longitudinal and transverse uniformity in a single irradiation. In this regime, proof-of-principle irradiation of patient-derived glioblastoma stem-like cells and human skin fibroblast cells show indications of a differential cellular response, when compared to reference irradiations at conventional dose-rates. These include a statistically significant increase in relative biological effectiveness ($1.40\pm0.08$ at 50\% survival for both cell lines) and a significant reduction of the relative radioresistance of tumour cells. Data analysis provides preliminary indications that these effects might not be fully explained by induced oxygen depletion in the cells but may be instead linked to a higher complexity of the damages triggered by the ultra-high density of ionising tracks of femtosecond-scale radiation pulses. These results demonstrate an integrated platform for systematic radiobiological studies at unprecedented beam durations and dose-rates, a unique infrastructure for translational research in radiobiology at the femtosecond scale.

physics.med-ph↗

arXiv2022

Surface Plasmon-Driven Electron and Proton Acceleration without Grating Coupling

Surface plasmon (SP) excitation in intense laser interaction with solid target can be exploited for enhancing secondary emissions, in particular efficient acceleration of high charge electron bunches. Previous studies have mostly used grating coupling to allow SP excitation, which requires stringent laser contrast conditions to preserve the structural integrity of the target. Here we show via simulations that efficient SP electron acceleration for currently available short pulse lasers can occur in a flat foil irradiated at parallel or grazing incidence ($\sim 5^\circ$ with the target surface) without a surface modulation. In turn, the accelerated electrons can be effective for generating proton beams with narrow spectra peaked at $>$100 MeV energies for currently available laser drivers.

physics.plasm-ph↗