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J. T. Cox

Publications and source records attributed to J. T. Cox.

2 recordsLinked to original sources

Evolutionary Games on the Torus with Weak Selection

We study evolutionary games on the torus with $N$ points in dimensions $d\ge 3$. The matrices have the form $\bar G = {\bf 1} + w G$, where ${\bf 1}$ is a matrix that consists of all 1's, and $w$ is small. As in Cox Durrett and Perkins \cite{CDP} we rescale time and space and take a limit as $N\to\infty$ and $w\to 0$. If (i) $w \gg N^{-2/d}$ then the limit is a PDE on ${\bf R}^d$. If (ii) $N^{-2/d} \gg w \gg N^{-1}$, then the limit is an ODE. If (iii) $w \ll N^{-1}$ then the effect of selection vanishes in the limit. In regime (ii) if we introduce a mutation $μ$ so that $μ/w \to \infty$ slowly enough then we arrive at Tarnita's formula that describes how the equilibrium frequencies are shifted due to selection.

math.PR

A stochastic model for the evolution of the influenza virus

Consider a birth and death chain to model the number of types of a given virus. Each type gives birth to a new type at rate $λ$ and dies at rate 1. Each type is also assigned a fitness. When a death occurs either the least fit type dies (with probability $1-r$) or we kill a type at random (with probability $r$). We show that this random killing has a large effect (for any $r>0$) on the behavior of the model when $λ<1$. The behavior of the model with $r>0$ and $λ<1$ is consistent with features of the phylogenetic tree of influenza.

math.PR