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Jace Grandinetti

Publications and source records attributed to Jace Grandinetti.

2 recordsLinked to original sources

From Generalist to Specialist: Improving Large Language Models for Medical Physics Using ARCoT

Large Language Models (LLMs) have achieved remarkable progress, yet their application in specialized fields, such as medical physics, remains challenging due to the need for domain-specific knowledge. This study introduces ARCoT (Adaptable Retrieval-based Chain of Thought), a framework designed to enhance the domain-specific accuracy of LLMs without requiring fine-tuning or extensive retraining. ARCoT integrates a retrieval mechanism to access relevant domain-specific information and employs step-back and chain-of-thought prompting techniques to guide the LLM's reasoning process, ensuring more accurate and context-aware responses. Benchmarking on a medical physics multiple-choice exam, our model outperformed standard LLMs and reported average human performance, demonstrating improvements of up to 68% and achieving a high score of 90%. This method reduces hallucinations and increases domain-specific performance. The versatility and model-agnostic nature of ARCoT make it easily adaptable to various domains, showcasing its significant potential for enhancing the accuracy and reliability of LLMs in specialized fields.

cs.CL

Top-level Design and Simulated Performance of the First Portable CT-MR scanner

Multi-modality imaging hardware can be integrated in a single gantry to collect diverse datasets for complementary information and spatiotemporal correlation, with excellent examples including PET-CT and PET-MRI. However, there is no CT-MRI prototype up to today due to technical challenges and associated cost-benefit considerations. Thanks to the rapid development of medical imaging, it becomes feasible now to integrate cost-effective CT and MRI imagers together for portability, popularity, and point of care. In this paper, we present the top-level design of the first portable CT-MRI system and evaluate its imaging performance via realistic numerical simulations. In this CT-MRI system, the magnet made of two NdFeB rings of about 40.0 cm radius forms a magnetic field of about 57 mT at the isocenter and has a gap of 11.3 cm to accommodate the rotating CT gantry. The targeted MR imaging field of view (FOV) is a sphere of ~15 cm in diameter and that of CT is approximately 20 cm diameter in axial direction and 5 cm in longitudinal direction. Our results show a great potential of such a hybrid system. The proposed CT-MRI system will be valuable in applications such as imaging in underdeveloped countries, disaster scenes and battle fields.

physics.med-ph