arXiv subjects

Jacek Urbanek

Publications and source records attributed to Jacek Urbanek.

4 recordsLinked to original sources

arXiv2023

Application of de-shape synchrosqueezing to estimate gait cadence from a single-sensor accelerometer placed in different body locations

Objective: Commercial and research-grade wearable devices have become increasingly popular over the past decade. Information extracted from devices using accelerometers is frequently summarized as ``number of steps" (commercial devices) or ``activity counts" (research-grade devices). Raw accelerometry data that can be easily extracted from accelerometers used in research, for instance ActiGraph GT3X+, are frequently discarded. Approach: Our primary goal is proposing an innovative use of the {\em de-shape synchrosqueezing transform} to analyze the raw accelerometry data recorded from a single sensor installed in different body locations, particularly the wrist, to extract {\em gait cadence} when a subject is walking. The proposed methodology is tested on data collected in a semi-controlled experiment with 32 participants walking on a one-kilometer predefined course. Walking was executed on a flat surface as well as on the stairs (up and down). Main Results: The cadences of walking on a flat surface, ascending stairs, and descending stairs, determined from the wrist sensor, are 1.98$\pm$0.15 Hz, 1.99$\pm$0.26 Hz, and 2.03$\pm$0.26 Hz respectively. The cadences are 1.98$\pm$0.14 Hz, 1.97$\pm$0.25 Hz, and 2.02$\pm$0.23 Hz, respectively if determined from the hip sensor, 1.98$\pm$0.14 Hz, 1.93$\pm$0.22 Hz and 2.06$\pm$0.24 Hz, respectively if determined from the left ankle sensor, and 1.98$\pm$0.14 Hz, 1.97$\pm$0.22 Hz, and 2.04$\pm$0.24 Hz, respectively if determined from the right ankle sensor. The difference is statistically significant indicating that the cadence is fastest while descending stairs and slowest when ascending stairs. Also, the standard deviation when the sensor is on the wrist is larger. These findings are in line with our expectations. Conclusion: We show that our proposed algorithm can extract the cadence with high accuracy, even when the sensor is placed on the wrist.

stat.AP↗

arXiv2022

Shape-constrained Estimation in Functional Regression with Bernstein Polynomials

Shape restrictions on functional regression coefficients such as non-negativity, monotonicity, convexity or concavity are often available in the form of a prior knowledge or required to maintain a structural consistency in functional regression models. A new estimation method is developed in shape-constrained functional regression models using Bernstein polynomials. Specifically, estimation approaches from nonparametric regression are extended to functional data, properly accounting for shape-constraints in a large class of functional regression models such as scalar-on-function regression (SOFR), function-on-scalar regression (FOSR), and function-on-function regression (FOFR). Theoretical results establish the asymptotic consistency of the constrained estimators under standard regularity conditions. A projection based approach provides point-wise asymptotic confidence intervals for the constrained estimators. A bootstrap test is developed facilitating testing of the shape constraints. Numerical analysis using simulations illustrate improvement in efficiency of the estimators from the use of the proposed method under shape constraints. Two applications include i) modeling a drug effect in a mental health study via shape-restricted FOSR and ii) modeling subject-specific quantile functions of accelerometry-estimated physical activity in the Baltimore Longitudinal Study of Aging (BLSA) as outcomes via shape-restricted quantile-function on scalar regression (QFOSR). R software implementation and illustration of the proposed estimation method and the test is provided.

stat.ME↗

arXiv2021

Distributional data analysis via quantile functions and its application to modelling digital biomarkers of gait in Alzheimer's Disease

With the advent of continuous health monitoring with wearable devices, users now generate their unique streams of continuous data such as minute-level step counts or heartbeats. Summarizing these streams via scalar summaries often ignores the distributional nature of wearable data and almost unavoidably leads to the loss of critical information. We propose to capture the distributional nature of wearable data via user-specific quantile functions (QF) and use these QFs as predictors in scalar-on-quantile-function-regression (SOQFR). As an alternative approach, we also propose to represent QFs via user-specific L-moments, robust rank-based analogs of traditional moments, and use L-moments as predictors in SOQFR (SOQFR-L). These two approaches provide two mutually consistent interpretations: in terms of quantile levels by SOQFR and in terms of L-moments by SOQFR-L. We also demonstrate how to deal with multi-modal distributional data via Joint and Individual Variation Explained (JIVE) using L-moments. The proposed methods are illustrated in a study of association of digital gait biomarkers with cognitive function in Alzheimer's disease (AD). Our analysis shows that the proposed methods demonstrate higher predictive performance and attain much stronger associations with clinical cognitive scales compared to simple distributional summaries.

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arXiv2021

Scalar on time-by-distribution regression and its application for modelling associations between daily-living physical activity and cognitive functions in Alzheimer's Disease

Wearable data is a rich source of information that can provide deeper understanding of links between human behaviours and human health. Existing modelling approaches use wearable data summarized at subject level via scalar summaries using regression techniques, temporal (time-of-day) curves using functional data analysis (FDA), and distributions using distributional data analysis (DDA). We propose to capture temporally local distributional information in wearable data using subject-specific time-by-distribution (TD) data objects. Specifically, we propose scalar on time-by-distribution regression (SOTDR) to model associations between scalar response of interest such as health outcomes or disease status and TD predictors. We show that TD data objects can be parsimoniously represented via a collection of time-varying L-moments that capture distributional changes over the time-of-day. The proposed method is applied to the accelerometry study of mild Alzheimer's disease (AD). Mild AD is found to be significantly associated with reduced maximal level of physical activity, particularly during morning hours. It is also demonstrated that TD predictors attain much stronger associations with clinical cognitive scales of attention, verbal memory, and executive function when compared to predictors summarized via scalar total activity counts, temporal functional curves, and quantile functions. Taken together, the present results suggest that the SOTDR analysis provides novel insights into cognitive function and AD.

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