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Jacob McErlean

Publications and source records attributed to Jacob McErlean.

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Functional Estimation of Manifold-Valued Diffusion Processes

Nonstationary high-dimensional time series are increasingly encountered in biomedical research as measurement technologies advance. Owing to the homeostatic nature of physiological systems, such datasets are often located on, or can be well approximated by, a low-dimensional manifold. Modeling such datasets by manifold-valued It\^o diffusion processes has been shown to provide valuable insights and to guide the design of algorithms for clinical applications. In this paper, we propose Nadaraya-Watson type nonparametric estimators for the drift vector field and diffusion matrix of the process from one trajectory. Assuming a time-homogeneous stochastic differential equation on a smooth complete manifold without boundary, we show that as the sampling interval and kernel bandwidth vanish with increasing trajectory length, recurrence of the process yields asymptotic consistency and normality of the drift and diffusion estimators, as well as the associated occupation density. Analysis of the diffusion estimator further produces a tangent space estimator for dependent data, which has its own interest and is essential for drift estimation. Numerical experiments across a range of manifold configurations support the theoretical results.

stat.ME

Lower Bounds on Volumes of Hyperbolic 3-Manifolds via Decomposition

In a variety of settings we provide a method for decomposing a 3-manifold $M$ into pieces. When the pieces have the appropriate type of hyperbolicity, then the manifold $M$ is hyperbolic and its volume is bounded below by the sum of the appropriately defined hyperbolic volumes of the pieces. A variety of examples of appropriately hyperbolic pieces and volumes are provided, with many examples from link complements in the 3-sphere.

math.GT

Generalized Augmented Cellular Alternating Links in Thickened Surfaces are Hyperbolic

Menasco proved that nontrivial links in the 3-sphere with connected prime alternating non-2-braid projections are hyperbolic. This was further extended to augmented alternating links wherein non-isotopic trivial components bounding disks punctured twice by the alternating link were added. Lackenby proved that the first and second collections of links together form a closed subset of the set of all finite volume hyperbolic 3-manifolds in the geometric topology. Adams showed hyperbolicity for generalized augmented alternating links, which include additional trivial components that bound n-punctured disks for $n \geq 2$. Here we prove that generalized augmented cellular alternating links in I-bundles over closed surfaces are also hyperbolic and that in $S \times I$, the cellular alternating links and the augmented cellular alternating together form a closed subset of finite volume hyperbolic 3-manifolds in the geometric topology. Explicit examples of additional links in $S \times I$ to which these results apply are included.

math.GT

Unsupervised Ensembling of Multiple Software Sensors with Phase Synchronization: A Robust Approach For Electrocardiogram-derived Respiration

Objective: We aimed to fuse the outputs of different electrocardiogram-derived respiration (EDR) algorithms to create one EDR signal that is of higher quality. Methods: We viewed each EDR algorithm as a software sensor that recorded breathing activity from a different vantage point, identified high-quality software sensors based on the respiratory signal quality index, aligned the highest-quality EDRs with a phase synchronization technique based on the graph connection Laplacian, and finally fused those aligned, high-quality EDRs. We refer to the output as the sync-ensembled EDR signal. The proposed algorithm was evaluated on two large-scale databases of whole-night polysomnograms. We evaluated the performance of the proposed algorithm using three respiratory signals recorded from different hardware sensors, and compared it with other existing EDR algorithms. A sensitivity analysis was carried out for a total of five cases: fusion by taking the mean of EDR signals, and the four cases of EDR signal alignment without and with synchronization and without and with signal quality selection. Results: The sync-ensembled EDR algorithm outperforms existing EDR algorithms when evaluated by the synchronized correlation ({\gamma}-score), optimal transport (OT) distance, and estimated average respiratory rate (EARR) score, all with statistical significance. The sensitivity analysis shows that the signal quality selection and EDR signal alignment are both critical for the performance, both with statistical significance. Conclusion: The sync-ensembled EDR provides robust respiratory information from electrocardiogram. Significance: Phase synchronization is not only theoretically rigorous but also practical to design a robust EDR.

eess.SP