arXiv subjects

James Jones

Publications and source records attributed to James Jones.

4 recordsLinked to original sources

arXiv2025

Evaluating Foundation Models with Pathological Concept Learning for Kidney Cancer

To evaluate the translational capabilities of foundation models, we develop a pathological concept learning approach focused on kidney cancer. By leveraging TNM staging guidelines and pathology reports, we build comprehensive pathological concepts for kidney cancer. Then, we extract deep features from whole slide images using foundation models, construct pathological graphs to capture spatial correlations, and trained graph neural networks to identify these concepts. Finally, we demonstrate the effectiveness of this approach in kidney cancer survival analysis, highlighting its explainability and fairness in identifying low- and high-risk patients. The source code has been released by https://github.com/shangqigao/RadioPath.

cs.AI↗

arXiv2025

SurvSurf: a partially monotonic neural network for first-hitting time prediction of intermittently observed discrete and continuous sequential events

We propose a neural-network based survival model (SurvSurf) specifically designed for direct and simultaneous probabilistic prediction of the first hitting time of sequential events from baseline. Unlike existing models, SurvSurf is theoretically guaranteed to never violate the monotonic relationship between the cumulative incidence functions of sequential events, while allowing nonlinear influence from predictors. It also incorporates implicit truths for unobserved intermediate events in model fitting, and supports both discrete and continuous time and events. We also identified a variant of the Integrated Brier Score (IBS) that showed robust correlation with the mean squared error (MSE) between the true and predicted probabilities by accounting for implied truths about the missing intermediate events. We demonstrated the superiority of SurvSurf compared to modern and traditional predictive survival models in two simulated datasets and two real-world datasets, using MSE, the more robust IBS and by measuring the extent of monotonicity violation.

stat.ML↗

arXiv2024

Demand and Capacity Modeling for Advanced Air Mobility

Advanced Air Mobility encompasses emerging aviation technologies that transport people and cargo between local, regional, or urban locations that are currently underserved by aviation and other transportation modalities. The disruptive nature of these technologies has pushed industry, academia, and governments to devote significant investments to understand their impact on airspace risk, operational procedures, and passengers. A flexible framework was designed to assess the operational viability of these technologies and the sensitivity to a variety of assumptions. This framework is used to simulate air taxi traffic within New York City by replacing a portion of the city's taxi requests with trips taken with electric vertical takeoff and landing vehicles and evaluate the sensitivity of passenger trip time to a variety of system wide assumptions. In particular, the paper focuses on the impact of the passenger capacity, landing site vehicle capacity, and fleet size. The operation density is then compared with the current air traffic to assess operation constraints that will challenge the network UAM operations.

physics.soc-ph↗

arXiv2021

Using Temperature Sensitivity to Estimate Shiftable Electricity Demand: Implications for power system investments and climate change

Growth of intermittent renewable energy and climate change make it increasingly difficult to manage electricity demand variability. Centralized storage can help but is costly. An alternative is to shift demand. Cooling and heating demands are substantial and can be economically shifted using thermal storage. To estimate what thermal storage, employed at scale, might do to reshape electricity loads, we pair fine-scale weather data with hourly electricity use to estimate the share of temperature-sensitive demand across 31 regions that span the continental United States. We then show how much variability can be reduced by shifting temperature-sensitive loads, with and without improved transmission between regions. We find that approximately three quarters of within-day, within-region demand variability can be eliminated by shifting just half of temperature-sensitive demand. The variability-reducing benefits of shifting temperature-sensitive demand complement those gained from improved interregional transmission, and greatly mitigate the challenge of serving higher peaks under climate change.

eess.SY↗