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Jane Garrison

Publications and source records attributed to Jane Garrison.

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Contrastive-Adversarial and Diffusion: Exploring pre-training and fine-tuning strategies for sulcal identification

In the last decade, computer vision has witnessed the establishment of various training and learning approaches. Techniques like adversarial learning, contrastive learning, diffusion denoising learning, and ordinary reconstruction learning have become standard, representing state-of-the-art methods extensively employed for fully training or pre-training networks across various vision tasks. The exploration of fine-tuning approaches has emerged as a current focal point, addressing the need for efficient model tuning with reduced GPU memory usage and time costs while enhancing overall performance, as exemplified by methodologies like low-rank adaptation (LoRA). Key questions arise: which pre-training technique yields optimal results - adversarial, contrastive, reconstruction, or diffusion denoising? How does the performance of these approaches vary as the complexity of fine-tuning is adjusted? This study aims to elucidate the advantages of pre-training techniques and fine-tuning strategies to enhance the learning process of neural networks in independent identical distribution (IID) cohorts. We underscore the significance of fine-tuning by examining various cases, including full tuning, decoder tuning, top-level tuning, and fine-tuning of linear parameters using LoRA. Systematic summaries of model performance and efficiency are presented, leveraging metrics such as accuracy, time cost, and memory efficiency. To empirically demonstrate our findings, we focus on a multi-task segmentation-classification challenge involving the paracingulate sulcus (PCS) using different 3D Convolutional Neural Network (CNN) architectures by using the TOP-OSLO cohort comprising 596 subjects.

eess.IV

An explainable three dimension framework to uncover learning patterns: A unified look in variable sulci recognition

The significant features identified in a representative subset of the dataset during the learning process of an artificial intelligence model are referred to as a 'global' explanation. 3D global explanations are crucial in neuroimaging, where a complex representational space demands more than basic 2D interpretations. However, current studies in the literature often lack the accuracy, comprehensibility, and 3D global explanations needed in neuroimaging and beyond. To address this gap, we developed an explainable artificial intelligence (XAI) 3D-Framework capable of providing accurate, low-complexity global explanations. We evaluated the framework using various 3D deep learning models trained on a well-annotated cohort of 596 structural MRIs. The binary classification task focused on detecting the presence or absence of the paracingulate sulcus, a highly variable brain structure associated with psychosis. Our framework integrates statistical features (Shape) and XAI methods (GradCam and SHAP) with dimensionality reduction, ensuring that explanations reflect both model learning and cohort-specific variability. By combining Shape, GradCam, and SHAP, our framework reduces inter-method variability, enhancing the faithfulness and reliability of global explanations. These robust explanations facilitated the identification of critical sub-regions, including the posterior temporal and internal parietal regions, as well as the cingulate region and thalamus, suggesting potential genetic or developmental influences. Our XAI 3D-Framework leverages global explanations to uncover the broader developmental context of specific cortical features. This approach advances the fields of deep learning and neuroscience by offering insights into normative brain development and atypical trajectories linked to mental illness, paving the way for more reliable and interpretable AI applications in neuroimaging.

cs.CV