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Jay M. Levin

Publications and source records attributed to Jay M. Levin.

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Fully Automated Deep Learning Based Glenoid Bone Loss Measurement and Severity Stratification on 3D CT in Shoulder Instability

To develop and validate a fully automated, deep-learning pipeline for measuring glenoid bone loss on 3D CT scans using linear-based, en-face view, and best-circle method. Shoulder CT scans of 81 patients were retrospectively collected between January 2013 and March 2023. Our algorithm consists of three main stages: (1) Segmentation, where we developed a U-Net to automatically segment the glenoid and humerus; (2) anatomical landmark detection, where a second network predicts glenoid rim points; and (3) geometric fitting, where we applied a principal component analysis (PCA), projection, and circle fitting to compute the percentage of bone loss. The performance of the pipeline was evaluated using DSC for segmentation and MAE and ICC for bone-loss measurement; intermediate outputs (rim point sets and en-face view) were also assessed. Automated measurements showed strong agreement with consensus readings, exceeding surgeon-to-surgeon consistency (ICC 0.84 vs 0.78 for all patients; ICC 0.71 vs 0.63 for low bone loss; ICC 0.83 vs 0.21 for high bone loss; P < 0.001). For the classification task of assigning each patient to different bone loss severity subgroups, the pipeline's sensitivity was 71.4% for the low-severity group and 85.7% for the high-severity group, with no instances of misclassifying low as high or vice versa. A fully automated, deep learning-based pipeline for glenoid bone-loss measurement on CT scans can be a clinically reliable tool to assist clinicians with preoperative planning for shoulder instability. We are releasing our model and dataset at https://github.com/Edenliu1/Auto-Glenoid-Measurement-DL-Pipeline .

cs.CV

SegmentAnyBone: A Universal Model that Segments Any Bone at Any Location on MRI

Magnetic Resonance Imaging (MRI) is pivotal in radiology, offering non-invasive and high-quality insights into the human body. Precise segmentation of MRIs into different organs and tissues would be highly beneficial since it would allow for a higher level of understanding of the image content and enable important measurements, which are essential for accurate diagnosis and effective treatment planning. Specifically, segmenting bones in MRI would allow for more quantitative assessments of musculoskeletal conditions, while such assessments are largely absent in current radiological practice. The difficulty of bone MRI segmentation is illustrated by the fact that limited algorithms are publicly available for use, and those contained in the literature typically address a specific anatomic area. In our study, we propose a versatile, publicly available deep-learning model for bone segmentation in MRI across multiple standard MRI locations. The proposed model can operate in two modes: fully automated segmentation and prompt-based segmentation. Our contributions include (1) collecting and annotating a new MRI dataset across various MRI protocols, encompassing over 300 annotated volumes and 8485 annotated slices across diverse anatomic regions; (2) investigating several standard network architectures and strategies for automated segmentation; (3) introducing SegmentAnyBone, an innovative foundational model-based approach that extends Segment Anything Model (SAM); (4) comparative analysis of our algorithm and previous approaches; and (5) generalization analysis of our algorithm across different anatomical locations and MRI sequences, as well as an external dataset. We publicly release our model at https://github.com/mazurowski-lab/SegmentAnyBone.

eess.IV