arXiv subjects

Jeffery A. Goldstein

Publications and source records attributed to Jeffery A. Goldstein.

6 recordsLinked to original sources

arXiv2026

RulerNet: Learning Perspective-Invariant Ruler Representations for Robust Image Scale Estimation

Accurately converting pixel measurements into absolute real-world dimensions remains a fundamental challenge in computer vision, limiting progress in applications such as biomedicine, forensics, nutritional analysis, and e-commerce. We introduce RulerNet, a deep learning framework that robustly infers scale in the wild by reformulating ruler reading as a unified keypoint detection problem and representing rulers with geometric progression parameters that compactly approximate the non-uniform spacing induced by perspective transformations. Unlike traditional methods that rely on handcrafted thresholds or rigid, ruler-specific pipelines, RulerNet directly localizes centimeter markings using a mark-visibility-based annotation and training strategy that remains valid under mark-preserving transformations, enabling strong generalization across diverse ruler types and imaging conditions while mitigating data scarcity. Additionally, we introduce a scalable synthetic data generation pipeline that combines graphics-based ruler creation with ControlNet-enhanced realism, significantly expanding training diversity and improving model performance. Extensive experiments on both our datasets and public benchmarks demonstrate that RulerNet achieves accurate, consistent, and efficient scale estimation under challenging real-world conditions. Integration into a medical analysis pipeline further demonstrates its practical utility for scale-aware measurement. These results suggest that RulerNet can serve as a generalizable measurement component and be readily integrated with other vision modules, such as segmentation, monocular depth estimation, and diagnostic workflows, for automated analysis in medical and other domains. An online demo is provided. The project page is at https://github.com/ymp5078/RulerNet.

cs.CV↗

arXiv2025

VLCD: Vision-Language Contrastive Distillation for Accurate and Efficient Automatic Placenta Analysis

Pathological examination of the placenta is an effective method for detecting and mitigating health risks associated with childbirth. Recent advancements in AI have enabled the use of photographs of the placenta and pathology reports for detecting and classifying signs of childbirth-related pathologies. However, existing automated methods are computationally extensive, which limits their deployability. We propose two modifications to vision-language contrastive learning (VLC) frameworks to enhance their accuracy and efficiency: (1) text-anchored vision-language contrastive knowledge distillation (VLCD)-a new knowledge distillation strategy for medical VLC pretraining, and (2) unsupervised predistillation using a large natural images dataset for improved initialization. Our approach distills efficient neural networks that match or surpass the teacher model in performance while achieving model compression and acceleration. Our results showcase the value of unsupervised predistillation in improving the performance and robustness of our approach, specifically for lower-quality images. VLCD serves as an effective way to improve the efficiency and deployability of medical VLC approaches, making AI-based healthcare solutions more accessible, especially in resource-constrained environments.

cs.CV↗

arXiv2024

S2S2: Semantic Stacking for Robust Semantic Segmentation in Medical Imaging

Robustness and generalizability in medical image segmentation are often hindered by scarcity and limited diversity of training data, which stands in contrast to the variability encountered during inference. While conventional strategies -- such as domain-specific augmentation, specialized architectures, and tailored training procedures -- can alleviate these issues, they depend on the availability and reliability of domain knowledge. When such knowledge is unavailable, misleading, or improperly applied, performance may deteriorate. In response, we introduce a novel, domain-agnostic, add-on, and data-driven strategy inspired by image stacking in image denoising. Termed ``semantic stacking,'' our method estimates a denoised semantic representation that complements the conventional segmentation loss during training. This method does not depend on domain-specific assumptions, making it broadly applicable across diverse image modalities, model architectures, and augmentation techniques. Through extensive experiments, we validate the superiority of our approach in improving segmentation performance under diverse conditions. Code is available at https://github.com/ymp5078/Semantic-Stacking.

cs.CV↗

arXiv2024

Deep Learning for Fetal Inflammatory Response Diagnosis in the Umbilical Cord

Inflammation of the umbilical cord can be seen as a result of ascending intrauterine infection or other inflammatory stimuli. Acute fetal inflammatory response (FIR) is characterized by infiltration of the umbilical cord by fetal neutrophils, and can be associated with neonatal sepsis or fetal inflammatory response syndrome. Recent advances in deep learning in digital pathology have demonstrated favorable performance across a wide range of clinical tasks, such as diagnosis and prognosis. In this study we classified FIR from whole slide images (WSI). We digitized 4100 histological slides of umbilical cord stained with hematoxylin and eosin(H&E) and extracted placental diagnoses from the electronic health record. We build models using attention-based whole slide learning models. We compared strategies between features extracted by a model (ConvNeXtXLarge) pretrained on non-medical images (ImageNet), and one pretrained using histopathology images (UNI). We trained multiple iterations of each model and combined them into an ensemble. The predictions from the ensemble of models trained using UNI achieved an overall balanced accuracy of 0.836 on the test dataset. In comparison, the ensembled predictions using ConvNeXtXLarge had a lower balanced accuracy of 0.7209. Heatmaps generated from top accuracy model appropriately highlighted arteritis in cases of FIR 2. In FIR 1, the highest performing model assigned high attention to areas of activated-appearing stroma in Wharton's Jelly. However, other high-performing models assigned attention to umbilical vessels. We developed models for diagnosis of FIR from placental histology images, helping reduce interobserver variability among pathologists. Future work may examine the utility of these models for identifying infants at risk of systemic inflammatory response or early onset neonatal sepsis.

eess.IV↗

arXiv2024

Machine learning identification of maternal inflammatory response and histologic choroamnionitis from placental membrane whole slide images

The placenta forms a critical barrier to infection through pregnancy, labor and, delivery. Inflammatory processes in the placenta have short-term, and long-term consequences for offspring health. Digital pathology and machine learning can play an important role in understanding placental inflammation, and there have been very few investigations into methods for predicting and understanding Maternal Inflammatory Response (MIR). This work intends to investigate the potential of using machine learning to understand MIR based on whole slide images (WSI), and establish early benchmarks. To that end, we use Multiple Instance Learning framework with 3 feature extractors: ImageNet-based EfficientNet-v2s, and 2 histopathology foundation models, UNI and Phikon to investigate predictability of MIR stage from histopathology WSIs. We also interpret predictions from these models using the learned attention maps from these models. We also use the MIL framework for predicting white blood cells count (WBC) and maximum fever temperature ($T_{max}$). Attention-based MIL models are able to classify MIR with a balanced accuracy of up to 88.5% with a Cohen's Kappa ($κ$) of up to 0.772. Furthermore, we found that the pathology foundation models (UNI and Phikon) are both able to achieve higher performance with balanced accuracy and $κ$, compared to ImageNet-based feature extractor (EfficientNet-v2s). For WBC and $T_{max}$ prediction, we found mild correlation between actual values and those predicted from histopathology WSIs. We used MIL framework for predicting MIR stage from WSIs, and compared effectiveness of foundation models as feature extractors, with that of an ImageNet-based model. We further investigated model failure cases and found them to be either edge cases prone to interobserver variability, examples of pathologist's overreach, or mislabeled due to processing errors.

cs.CV↗

arXiv2023

AI-SAM: Automatic and Interactive Segment Anything Model

Semantic segmentation is a core task in computer vision. Existing methods are generally divided into two categories: automatic and interactive. Interactive approaches, exemplified by the Segment Anything Model (SAM), have shown promise as pre-trained models. However, current adaptation strategies for these models tend to lean towards either automatic or interactive approaches. Interactive methods depend on prompts user input to operate, while automatic ones bypass the interactive promptability entirely. Addressing these limitations, we introduce a novel paradigm and its first model: the Automatic and Interactive Segment Anything Model (AI-SAM). In this paradigm, we conduct a comprehensive analysis of prompt quality and introduce the pioneering Automatic and Interactive Prompter (AI-Prompter) that automatically generates initial point prompts while accepting additional user inputs. Our experimental results demonstrate AI-SAM's effectiveness in the automatic setting, achieving state-of-the-art performance. Significantly, it offers the flexibility to incorporate additional user prompts, thereby further enhancing its performance. The project page is available at https://github.com/ymp5078/AI-SAM.

cs.CV↗