arXiv subjects

Jeremy C. Weiss

Publications and source records attributed to Jeremy C. Weiss.

24 records · Page 2Linked to original sources

arXiv2022

Longitudinal Fairness with Censorship

Recent works in artificial intelligence fairness attempt to mitigate discrimination by proposing constrained optimization programs that achieve parity for some fairness statistic. Most assume availability of the class label, which is impractical in many real-world applications such as precision medicine, actuarial analysis and recidivism prediction. Here we consider fairness in longitudinal right-censored environments, where the time to event might be unknown, resulting in censorship of the class label and inapplicability of existing fairness studies. We devise applicable fairness measures, propose a debiasing algorithm, and provide necessary theoretical constructs to bridge fairness with and without censorship for these important and socially-sensitive tasks. Our experiments on four censored datasets confirm the utility of our approach.

cs.LG↗

arXiv2021

FARF: A Fair and Adaptive Random Forests Classifier

As Artificial Intelligence (AI) is used in more applications, the need to consider and mitigate biases from the learned models has followed. Most works in developing fair learning algorithms focus on the offline setting. However, in many real-world applications data comes in an online fashion and needs to be processed on the fly. Moreover, in practical application, there is a trade-off between accuracy and fairness that needs to be accounted for, but current methods often have multiple hyperparameters with non-trivial interaction to achieve fairness. In this paper, we propose a flexible ensemble algorithm for fair decision-making in the more challenging context of evolving online settings. This algorithm, called FARF (Fair and Adaptive Random Forests), is based on using online component classifiers and updating them according to the current distribution, that also accounts for fairness and a single hyperparameters that alters fairness-accuracy balance. Experiments on real-world discriminated data streams demonstrate the utility of FARF.

cs.LG↗

arXiv2020

Unpacking the Drop in COVID-19 Case Fatality Rates: A Study of National and Florida Line-Level Data

Since the COVID-19 pandemic first reached the United States, the case fatality rate has fallen precipitously. Several possible explanations have been floated, including greater detection of mild cases due to expanded testing, shifts in age distribution among the infected, lags between confirmed cases and reported deaths, improvements in treatment, mutations in the virus, and decreased viral load as a result of mask-wearing. Using both Florida line-level data and recently released (but incomplete) national line level data from April 1, 2020 to November 1, 2020 on cases, hospitalizations, and deaths--each stratified by age--we unpack the drop in case fatality rate (CFR). Under the hypothesis that improvements in treatment efficacy should correspond to decreases in hospitalization fatality rate (HFR), we find that improvements in the national data do not always match the story told by Florida data. In the national data, treatment improvements between the first wave and the second wave appear substantial, but modest when compared to the drop in aggregate CFR. By contrast, possibly due to constrained resources in a much larger second peak, Florida data suggests comparatively little difference between the first and second wave, with HFR slightly increasing in every age group. However, by November 1st, both Florida and national data suggest significant decreases in age-stratified HFR since April 1st. By accounting for several confounding factors, our analysis shows how age-stratified HFR can provide a more realistic picture of treatment improvements than CFR. One key limitation of our analysis is that the national line-level data remains incomplete and plagued by artifacts. Our analysis highlights the crucial role that this data can play but also the pressing need for public, complete, and high-quality age-stratified line-level data for both cases, hospitalizations, and deaths for all states.

stat.AP↗

arXiv2020

Predicting Mortality Risk in Viral and Unspecified Pneumonia to Assist Clinicians with COVID-19 ECMO Planning

Respiratory complications due to coronavirus disease COVID-19 have claimed tens of thousands of lives in 2020. Many cases of COVID-19 escalate from Severe Acute Respiratory Syndrome (SARS-CoV-2) to viral pneumonia to acute respiratory distress syndrome (ARDS) to death. Extracorporeal membranous oxygenation (ECMO) is a life-sustaining oxygenation and ventilation therapy that may be used for patients with severe ARDS when mechanical ventilation is insufficient to sustain life. While early planning and surgical cannulation for ECMO can increase survival, clinicians report the lack of a risk score hinders these efforts. In this work, we leverage machine learning techniques to develop the PEER score, used to highlight critically ill patients with viral or unspecified pneumonia at high risk of mortality or decompensation in a subpopulation eligible for ECMO. The PEER score is validated on two large, publicly available critical care databases and predicts mortality at least as well as other existing risk scores. Stratifying our cohorts into low-risk and high-risk groups, we find that the high-risk group also has a higher proportion of decompensation indicators such as vasopressor and ventilator use. Finally, the PEER score is provided in the form of a nomogram for direct calculation of patient risk, and can be used to highlight at-risk patients among critical care patients eligible for ECMO.

stat.AP↗

arXiv2019

Harmonic Mean Point Processes: Proportional Rate Error Minimization for Obtundation Prediction

In healthcare, the highest risk individuals for morbidity and mortality are rarely those with the greatest modifiable risk. By contrast, many machine learning formulations implicitly attend to the highest risk individuals. We focus on this problem in point processes, a popular modeling technique for the analysis of the temporal event sequences in electronic health records (EHR) data with applications in risk stratification and risk score systems. We show that optimization of the log-likelihood function also gives disproportionate attention to high risk individuals and leads to poor prediction results for low risk individuals compared to ones at high risk. We characterize the problem and propose an adjusted log-likelihood formulation as a new objective for point processes. We demonstrate the benefits of our method in simulations and in EHR data of patients admitted to the critical care unit for intracerebral hemorrhage.

stat.ML↗

arXiv2017

Survival-Supervised Topic Modeling with Anchor Words: Characterizing Pancreatitis Outcomes

We introduce a new approach for topic modeling that is supervised by survival analysis. Specifically, we build on recent work on unsupervised topic modeling with so-called anchor words by providing supervision through an elastic-net regularized Cox proportional hazards model. In short, an anchor word being present in a document provides strong indication that the document is partially about a specific topic. For example, by seeing "gallstones" in a document, we are fairly certain that the document is partially about medicine. Our proposed method alternates between learning a topic model and learning a survival model to find a local minimum of a block convex optimization problem. We apply our proposed approach to predicting how long patients with pancreatitis admitted to an intensive care unit (ICU) will stay in the ICU. Our approach is as accurate as the best of a variety of baselines while being more interpretable than any of the baselines.

stat.ML↗