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Jiaming Liang

Publications and source records attributed to Jiaming Liang.

At least 19 recordsLinked to original sources

DeMixPert: Decomposed Response Modeling with Gaussian Mixtures for OOD Single-Cell Perturbation Prediction

Predicting transcriptome-wide responses to unseen genetic perturbations remains a major computational challenge because accurate prediction requires recovering both perturbation-specific transcriptional shifts and heterogeneous cellular responses. Existing methods often entangle deterministic response structure with stochastic population-level variation, causing dominant shared patterns to mask weaker perturbation-specific signals and impair distributional modeling. To address these challenges, we propose \textbf{DeMixPert}, an approach for Decomposed response Modeling with Gaussian Mixtures for Out-Of-Distribution (OOD) single-cell Perturbation prediction. DeMixPert decomposes perturbation-induced changes into a basal-state-dependent systematic response, a perturbation-specific response, and population-level variation. The systematic component is derived from the basal state encoded from control-cell expression, whereas the perturbation-specific component is inferred from pretrained target embeddings for unseen-target generalization. DeMixPert models population-level variation using a Gaussian prototype Invertible Network and adaptively combines reusable Gaussian prototypes according to the basal state and perturbation condition. The resulting mixture is mapped to a condition-specific variation distribution. Sampled variations are integrated with the systematic and perturbation-specific components, followed by joint decoding with the basal state to reconstruct perturbed-cell gene expression. Experimental results show that DeMixPert effectively captures heterogeneous single-cell perturbation responses and achieves superior performance across unseen-perturbation settings. The source code is made publicly available upon publication.

cs.LG

Fast Test-Time Refinement for Robust Learned Image Compression

Learned image compression (LIC) has demonstrated remarkable rate-distortion (RD) performance in benign settings. However, the high representational capacity endowed by deep neural networks (DNNs) comes at the expense of increased adversarial vulnerability. This hinders their adoption as trusted standardized codecs. Recent work has sketched test-time refinement (TTR) as a defense in gray-box scenarios, despite its original purpose of improving benign RD performance. Unfortunately, extensive iterations of TTR incur prohibitive overhead, while the robustness mechanism lacks theoretical understanding. Moreover, TTR has not been evaluated in white-box settings or against attacks beyond $\ell_2$-bounded rate and untargeted distortion objectives. To bridge these gaps, we present a systematic study. Our study reveals an Asymmetric Adversarial Trajectory (AAT) property in LIC systems: transitioning from adversarial to benign regions is significantly easier than the reverse process, where adversarial examples can often be roughly recovered within only 1-2 steps. We provide a two-dimensional Tube Model to explain this phenomenon. Based on AAT, we propose a Fast Test-Time Refinement (FTTR) framework for practical and robust LIC systems. We establish that the robustness arises from the contraction of adversarial regions induced by the Input-as-Label property of LIC systems, rather than from obfuscated gradients. Extensive evaluations with diverse strong adaptive attacks across multiple LIC systems demonstrate the promise of the proposed FTTR framework. The code is available at https://github.com/chinaliangjiaming/FTTR.git.

cs.CV

S$^3$-Diff: Structural Semantic Synergy Diffusion Model for High Fidelity Super Resolution of Pathological Images

Digital pathology relies on high-resolution whole slide images for accurate diagnosis, yet limitations in imaging devices, storage, and transmission often make lower-resolution pathology images more common in clinical workflows. Current super-resolution techniques often tend to smooth diagnostically relevant morphology, leading to over-smoothed textures and semantic drift that compromise downstream clinical interpretation. To this end, we develop the Structural Semantic Synergy Diffusion Model (S3-Diff), a diffusion framework for high-fidelity super-resolution of pathological images. The core of S3-Diff is Specimen-aware Structural Anchoring (SSA), which combines prognosis-aware tissue support extracted by a fixed SAM with LR-HR gradient discrepancies to generate a specimen-specific structural anchor to preserve pathological morphology. Concurrently, we introduce Structure-guided Semantic Fidelity Tuning (SSFT) to adapt DINOv3 representations using SSA-derived structural supervision. SSFT combines the adapted semantic energy with LR-derived edge and grayscale cues. The resulting control guides denoising to suppress stochastic artifacts and maintain structural consistency. Extensive experimental results demonstrate that S3-Diff consistently outperforms state-of-the-art methods in both reconstruction quality and downstream survival analysis performance. The source code will be made public.

cs.CV

Morphology-Aware Implicit Super-Resolution Network for Pathological Images

Accurate diagnosis in Digital Pathology (DP) relies on high-resolution whole-slide images, yet clinical deployment is often limited by hardware costs. Super-Resolution (SR) offers a promising alternative by computationally enhancing low-resolution acquisitions. However, existing SR methods frequently struggle to preserve fine-grained cellular morphology, leading to texture oversmoothing and blurred structural boundaries under complex tissue variability. To address this issue, we propose Morph-ISR, a morphology-aware implicit super-resolution framework for DP that restores diagnostically relevant details with sub-pixel precision. Morph-ISR reformulates SR as a continuous coordinate-based reconstruction problem and integrates an Implicit Position-aware Kernel Generator (IPKG) to adaptively model spatially varying tissue morphology. To further enhance structural fidelity, a Morphological Fidelity Prior (MFP) is introduced, leveraging semantic guidance from a pre-trained cell segmentation network to enforce boundary-preserving and region-aware reconstruction, thereby improving the representation of critical cellular boundaries and nuclear textures. Experiments on TCGA and SurGen datasets show that Morph-ISR achieves the best LPIPS and ST-LPIPS among the evaluated methods, reducing them by up to 38.37% and 39.55%, respectively, over the second-best methods while maintaining strong PSNR and SSIM. These results demonstrate superior preservation of diagnostically relevant cellular boundaries and nuclear textures, while compact parameterization and high throughput support efficient edge deployment. Code and trained models will be released upon publication.

cs.CV

CHM-Net: Center Heatmap-driven Macro-Micro Modeling Network for MRI-based Microbial Density Stratification

Microbial density is clinically important for tumor assessment and treatment decision-making, and recent advances in deep learning suggest that it can be non-invasively inferred from multimodal MRI. In this work, MRI-based Microbial Density Stratification (MRI-MDS) is first investigated as a patient-level representation learning task, and Center Heatmap-driven Macro-micro modeling Network (CHM-Net) is introduced for this task. CHM-Net first establishes the link between imaging phenotypes and microbial states through center heatmap-guided small-lesion response localization. Building upon this, it constructs patient-level macro-micro evidence from localized heatmap responses for microbial density prediction. Experiments on the novel GBNPC 2026 dataset constructed for MRI-MDS demonstrate the effectiveness of CHM-Net, achieving superior performance over representative baselines with a 12.06% absolute ACC gain over the strongest competing result. Additionally, auxiliary validation on two 3D medical image datasets further verifies its robustness across volumetric medical image classification scenarios. The project is available at https://anonymous.4open.science/r/CHM-Net-942E/.

eess.IV

JoyAI-Sim: A Simulation-Enabled Interconversion Toolchain for the Embodied Data Pyramid

Generalist robot policies require trustworthy evaluation and robot-usable training data, but both are difficult to scale with physical robots alone. Real-robot trials and demonstrations remain the most faithful source of deployment signals, yet they are slow, costly, and hard to reproduce. We present JoyAI-Sim, a simulation-enabled interconversion toolchain for human-robot aligned model evaluation and data generation, denoted as Robot $\rightleftharpoons$ Simulation $\rightleftharpoons$ Human. On the one hand, the Robot $\rightarrow$ Simulation $\rightarrow$ Human pathway supports human-robot aligned model evaluation by reconstructing real-robot tabletop organization tasks as calibrated digital twins for scalable evaluation, while using human embodied feedback to inspect and refine the naturalness of simulated motions. On the other hand, the Human $\rightarrow$ Simulation $\rightarrow$ Robot pathway supports human-robot aligned data generation: it lifts ego-centric human demonstrations into simulation, checks them under robot physical constraints, and converts them into robot-centered trajectories, annotations, and visual observations. Together, these pathways use the JoySim simulator as both a scalable evaluation layer and a physical consistency filter for robot data generation. We further package the core reconstruction, simulation, rendering, and realism-augmentation modules as cloud services on JD Cloud, turning the system into a reusable and scalable infrastructure for robot data generation and model evaluation.

cs.RO

Dimension-Free Complexity Guarantees for Dual Dynamic Programming

This paper studies the complexity of a dual dynamic programming (DDP) method for solving a class of convex optimization problems with linear coupling constraints. Existing complexity results based on DDP depend on the dimensions of the state vectors and, in particular, grow exponentially with dimension. The goal of this paper is to establish a complexity bound that is independent of the dimension. Our approach first studies an unconstrained strongly convex problem and develops a flexible framework for DDP, called FDDP, for solving the associated dynamic programming equations, and establishes an iteration-complexity bound for it that is independent of the dimension. A dimension-independent complexity bound for the original linearly constrained problem is then obtained by applying FDDP to a corresponding unconstrained strongly convex problem obtained via smoothing and penalization. Inspired by the literature on bundle methods, FDDP updates lower approximations of cost-to-go functions through a generic procedure that includes both the classical multi-cut DDP and a new two-cut DDP variant as special cases. The two-cut variant maintains only two affine cuts per stage at each iteration, making it more memory-efficient while retaining the same theoretical guarantees. Finally, numerical experiments illustrate the practical behavior of multi-cut and two-cut DDP, including their dependence on problem parameters and their performance relative to a direct quadratic constraint reformulation.

math.OC

ANCHOR: Agentic Noise Creation Framework for Human Simulation and Denoising Recommendation

Distilling accurate user preferences from noisy implicit feedback remains a fundamental bottleneck in recommendation systems, highlighting the need for recommendation denoising. However, real-world data lack explicit noise annotations, forcing existing methods to rely on unsupervised side information or handcrafted heuristics. These approaches often incur high external costs, generalize poorly, or depend on unreliable priors, causing noise misidentification and corrupting true user preference representations. To address these limitations, we propose a paradigm-level reformulation of recommendation denoising. Instead of indirectly inferring noisy interactions through heuristics, our Creation-Recognition paradigm proactively creates labeled noisy interactions and trains a dedicated recognizer to identify them, transforming denoising from heuristic filtering into supervised learning. Based on this paradigm, we present ANCHOR, an agent-based framework inspired by recent LLM-as-User research. ANCHOR simulates user behaviors to generate realistic noise labels and enables supervised denoising through two stages: noise creation and noise recognition. In the noise creation stage, ANCHOR adopts a recommender-in-the-loop agentic architecture to synthesize both diverse out-of-preference noise and informative boundary-adjacent noise. For out-of-preference noise, it implements five extensible simulation mechanisms to approximate major sources of noisy implicit feedback. For boundary-adjacent noise, an adversarial boundary refinement mechanism generates ambiguous interactions that challenge the recognizer and target the decision boundary. In the noise recognition stage, ANCHOR leverages the generated labels to train a reusable parametric recognizer that integrates collaborative signals and semantic representations to detect noise patterns in real interaction data.

cs.IR

Control Your View: High-Resolution Global Semantic Manipulation in Learned Image Compression

Learned image compression (LIC) integrates deep neural networks (DNNs) to map high-dimensional images into compact latent representations, reducing redundancy and achieving superior rate-distortion (RD) performance in benign settings. Unfortunately, due to inherent vulnerabilities in DNNs, LIC systems are susceptible to adversarial perturbations that lead to downstream deterioration, compression rate degradation, untargeted distortion, and both local semantic manipulation (LSM) and low-resolution ($3\times28\times28$) global semantic manipulation (GSM). However, high-resolution GSM remains unexplored due to its intractability. Notably, the existing project gradient descent (PGD) method achieves near-perfect white-box attacks for classification, segmentation, and other tasks, yet fails to generalize to high-resolution GSM. Our theoretical and empirical analyses reveal that well-performing GSM drives adversarial examples from the Identity Region to the Amplification Region through the Lazying-Oscillating-Refining stages. General $\ell_{\infty}$-bounded attacks fail on high-resolution GSM because their step-size schedules cannot accommodate both the Oscillating and Refining stages. Based on this, we propose the Periodic Geometric Decay schedule that enables $\ell_{\infty}$-bounded high-resolution GSM. To verify our approach, we integrate it with PGD, yielding a minimal variant, PGD$^{2}$-GSM. Extensive experiments on the Kodak $(3\times768\times512)$ demonstrate that our PGD$^{2}$-GSM is the first to stably achieve high-resolution GSM, thereby exposing a novel threat to LIC systems. Code is available at https://github.com/chinaliangjiaming/PGD2-GSM.

cs.CV

Self-Driving Datasets: From 20 Million Papers to Nuanced Biomedical Knowledge at Scale

Manually curated biomedical repositories -- spanning bioactivity, genomics, and chemistry -- are expensive to maintain, lag behind primary literature, and discard experimental context, obscuring nuances needed to assess data correctness and coverage. We show that PubMed itself can be autonomously and cost-effectively turned into structured datasets that are larger, more nuanced, and more accurate than the curated databases they replace. We present three coupled contributions: (1) an LLM-based entity-tagging pipeline, grounded in nine biomedical ontologies, that tags 4.5B entities across 19 categories in a 22.5M-paper, 2.5T-token PubMed corpus; (2) hybrid sparse-dense retrieval supporting entity-filtered semantic queries over the tagged corpus; and (3) Starling, a multi-agent deep research system that, given only a natural-language task description, designs precision- and recall-targeted retrieval filters, induces an extraction schema, and emits structured records with nuance-rich fields and supporting passages. Across six tasks -- blood-brain barrier permeability, oral bioavailability, acute toxicity (LD50), gene-disease associations, protein subcellular localization, and chemical reactions -- Starling produces ~6.3M records (91K-3M per task); several are, to our knowledge, the largest public datasets for their property. Frontier-model rejection of our extractions is 0.6-7.7% across tasks, far below error rates we measure on widely used curated counterparts (e.g., 16.5% on BBB_Martins, 7.3% on Bioavailability_Ma). Beyond scale and accuracy, the supporting passages carry nuance tabular databases discard -- e.g., oral bioavailability may depend on fed vs. fasted state. Together, the corpus, retrieval, and agent establish a foundation for AI-driven therapeutic design. Code and datasets: https://github.com/starling-labs/starling.

cs.LG

EgoLive: A Large-Scale Egocentric Dataset from Real-World Human Tasks

The advancement of robot learning is currently hindered by the scarcity of large-scale, high-quality datasets. While established data collection methods such as teleoperation and universal manipulation interfaces dominate current datasets, they suffer from inherent limitations in scalability and real-world deployability. Human egocentric video collection, by contrast, has emerged as a promising approach to enable scalable, natural and in-the-wild data collection. As such, we present EgoLive, a large-scale, high-quality egocentric dataset designed explicitly for robot manipulation learning. EgoLive establishes three distinctive technical advantages over existing egocentric datasets: first, it represents the largest open-source annotated egocentric dataset focused on real-world task-oriented human routines to date; second, it delivers leading data quality via a customized head-mounted capture device and comprehensive high-precision multi-modal annotations; third, all data is collected exclusively in unconstrained real-world scenarios and encompasses vertical field human working data, including home service, retail, and other practical work scenarios, providing superior diversity and ecological validity. With the introduction of EgoLive, we aim to provide the research community with a scalable, high-quality dataset that accelerates breakthroughs in generalizable robotic models and facilitates the real-world deployment of robot systems.

cs.RO

JoyAI-RA 0.1: A Foundation Model for Robotic Autonomy

Robotic autonomy in open-world environments is fundamentally limited by insufficient data diversity and poor cross-embodiment generalization. Existing robotic datasets are often limited in scale and task coverage, while relatively large differences across robot embodiments impede effective behavior knowledge transfer. To address these challenges, we propose JoyAI-RA, a vision-language-action (VLA) embodied foundation model tailored for generalizable robotic manipulation. JoyAI-RA presents a multi-source multi-level pretraining framework that integrates web data, large-scale egocentric human manipulation videos, simulation-generated trajectories, and real-robot data. Through training on heterogeneous multi-source data with explicit action-space unification, JoyAI-RA effectively bridges embodiment gaps, particularly between human manipulation and robotic control, thereby enhancing cross-embodiment behavior learning. JoyAI-RA outperforms state-of-the-art methods in both simulation and real-world benchmarks, especially on diverse tasks with generalization demands.

cs.RO

Accuracy Certificates for Convex Optimization at Accelerated Rates via Primal-Dual Averaging

Many works in convex optimization provide rates for achieving a small primal gap. However, this quantity is typically unavailable in practice. In this work, we show that solving a regularized surrogate with algorithms based on simple primal-dual averaging provides non-asymptotic convergence guarantees for a \textit{computable} optimality certificate. We first analyze primal and dual methods based on one average, namely modified dual averaging and generalized conditional gradient, and establish $\tilde{O}(\varepsilon^{-1})$ certificate complexities. Motivated by asymmetries in the one-average case, we analyze a self-dual, two-average method that preserves symmetry while losing certificate guarantees. To recover certificate convergence, we propose a three-average method that achieves an accelerated $\tilde{O}(\varepsilon^{-1/2})$ certificate complexity. Furthermore, we prove primal-dual algorithm correspondences for the one, two, and three-average cases. In particular, the primal three-average accelerated method mirrors the well-known gradient extrapolation method in the dual. By interpreting our results through the lens of zero-sum matrix games and Fisher markets, we further connect primal-dual averaging methods to game theory and market dynamics.

math.OC

SDDF: Specificity-Driven Dynamic Focusing for Open-Vocabulary Camouflaged Object Detection

Open-vocabulary object detection (OVOD) aims to detect known and unknown objects in the open world by leveraging text prompts. Benefiting from the emergence of large-scale vision--language pre-trained models, OVOD has demonstrated strong zero-shot generalization capabilities. However, when dealing with camouflaged objects, the detector often fails to distinguish and localize objects because the visual features of the objects and the background are highly similar. To bridge this gap, we construct a benchmark named OVCOD-D by augmenting carefully selected camouflaged object images with fine-grained textual descriptions. Due to the limited scale of available camouflaged object datasets, we adopt detectors pre-trained on large-scale object detection datasets as our baseline methods, as they possess stronger zero-shot generalization ability. In the specificity-aware sub-descriptions generated by multimodal large models, there still exist confusing and overly decorative modifiers. To mitigate such interference, we design a sub-description principal component contrastive fusion strategy that reduces noisy textual components. Furthermore, to address the challenge that the visual features of camouflaged objects are highly similar to those of their surrounding environment, we propose a specificity-guided regional weak alignment and dynamic focusing method, which aims to strengthen the detector's ability to discriminate camouflaged objects from background. Under the open-set evaluation setting, the proposed method achieves an AP of 56.4 on the OVCOD-D benchmark.

cs.CV

A Unified Spatial Alignment Framework for Highly Transferable Transformation-Based Attacks on Spatially Structured Tasks

Transformation-based adversarial attacks (TAAs) demonstrate strong transferability when deceiving classification models. However, existing TAAs often perform unsatisfactorily or even fail when applied to structured tasks such as semantic segmentation and object detection. Encouragingly, recent studies that categorize transformations into non-spatial and spatial transformations inspire us to address this challenge. We find that for non-structured tasks, labels are spatially non-structured, and thus TAAs are not required to adjust labels when applying spatial transformations. In contrast, for structured tasks, labels are spatially structured, and failing to transform labels synchronously with inputs can cause spatial misalignment and yield erroneous gradients. To address these issues, we propose a novel unified Spatial Alignment Framework (SAF) for highly transferable TAAs on spatially structured tasks, where the TAAs spatially transform labels synchronously with the input using the proposed Spatial Alignment (SA) algorithm. Extensive experiments demonstrate the crucial role of our SAF for TAAs on structured tasks. Specifically, in non-targeted attacks, our SAF degrades the average mIoU on Cityscapes from 24.50 to 11.34, and on Kvasir-SEG from 49.91 to 31.80, while reducing the average mAP of COCO from 17.89 to 5.25.

cs.CV

Efficient Preemptive Robustification with Image Sharpening

Despite their great success, deep neural networks rely on high-dimensional, non-robust representations, making them vulnerable to imperceptible perturbations, even in transfer scenarios. To address this, both training-time defenses (e.g., adversarial training and robust architecture design) and post-attack defenses (e.g., input purification and adversarial detection) have been extensively studied. Recently, a limited body of work has preliminarily explored a pre-attack defense paradigm, termed preemptive robustification, which introduces subtle modifications to benign samples prior to attack to proactively resist adversarial perturbations. Unfortunately, their practical applicability remains questionable due to several limitations, including (1) reliance on well-trained classifiers as surrogates to provide robustness priors, (2) substantial computational overhead arising from iterative optimization or trained generators for robustification, and (3) limited interpretability of the optimization- or generation-based robustification processes. Inspired by recent studies revealing a positive correlation between texture intensity and the robustness of benign samples, we show that image sharpening alone can efficiently robustify images. To the best of our knowledge, this is the first surrogate-free, optimization-free, generator-free, and human-interpretable robustification approach. Extensive experiments demonstrate that sharpening yields remarkable robustness gains with low computational cost, especially in transfer scenarios.

cs.CV

Beyond Viewpoint Generalization: What Multi-View Demonstrations Offer and How to Synthesize Them for Robot Manipulation?

Does multi-view demonstration truly improve robot manipulation, or merely enhance cross-view robustness? We present a systematic study quantifying the performance gains, scaling behavior, and underlying mechanisms of multi-view data for robot manipulation. Controlled experiments show that, under both fixed and randomized backgrounds, multi-view demonstrations consistently improve single-view policy success and generalization. Performance varies non-monotonically with view coverage, revealing effective regimes rather than a simple "more is better" trend. Notably, multi-view data breaks the scaling limitation of single-view datasets and continues to raise performance ceilings after saturation. Mechanistic analysis shows that multi-view learning promotes manipulation-relevant visual representations, better aligns the action head with the learned feature distribution, and reduces overfitting. Motivated by the importance of multi-view data and its scarcity in large-scale robotic datasets, as well as the difficulty of collecting additional viewpoints in real world settings, we propose RoboNVS, a geometry-aware self-supervised framework that synthesizes novel-view videos from monocular inputs. The generated data consistently improves downstream policies in both simulation and real-world environments.

cs.RO

Multilingual Safety Alignment Via Sparse Weight Editing

Large Language Models (LLMs) exhibit significant safety disparities across languages, with low-resource languages (LRLs) often bypassing safety guardrails established for high-resource languages (HRLs) like English. Existing solutions, such as multilingual supervised fine-tuning (SFT) or Reinforcement Learning from Human Feedback (RLHF), are computationally expensive and dependent on scarce multilingual safety data. In this work, we propose a novel, training-free alignment framework based on Sparse Weight Editing. Identifying that safety capabilities are localized within a sparse set of safety neurons, we formulate the cross-lingual alignment problem as a constrained linear transformation. We derive a closed-form solution to optimally map the harmful representations of LRLs to the robust safety subspaces of HRLs, while preserving general utility via a null-space projection constraint. Extensive experiments across 8 languages and multiple model families (Llama-3, Qwen-2.5) demonstrate that our method substantially reduces Attack Success Rate (ASR) in LRLs with negligible impact on general reasoning capabilities, all achieved with a single, data-efficient calculation.

cs.LG